Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DYY93_RS10750 Genome accession   NZ_LT996889
Coordinates   2113774..2114490 (-) Length   238 a.a.
NCBI ID   WP_115657841.1    Uniprot ID   -
Organism   Staphylococcus aureus isolate 24117-REV     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2108774..2119490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYY93_RS10730 - 2109866..2110816 (+) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -
  DYY93_RS10735 - 2110965..2112449 (+) 1485 WP_000141411.1 sucrose-6-phosphate hydrolase -
  DYY93_RS10740 - 2112446..2113405 (+) 960 WP_001253291.1 carbohydrate kinase family protein -
  DYY93_RS10745 - 2113593..2113702 (-) 110 Protein_2014 hypothetical protein -
  DYY93_RS10750 agrA 2113774..2114490 (-) 717 WP_115657841.1 quorum-sensing response regulator AgrA Regulator
  DYY93_RS10755 agrC 2114509..2115792 (-) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  DYY93_RS10760 agrD 2115822..2115965 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  DYY93_RS10765 - 2115949..2116584 (-) 636 WP_001641623.1 accessory gene regulator AgrB -
  DYY93_RS14350 hld 2116820..2116900 (+) 81 WP_000046022.1 delta-hemolysin -
  DYY93_RS10775 - 2117500..2118285 (-) 786 WP_000867950.1 carbon-nitrogen family hydrolase -
  DYY93_RS10780 - 2118646..2119272 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 28033.05 Da        Isoelectric Point: 6.3009

>NTDB_id=1150441 DYY93_RS10750 WP_115657841.1 2113774..2114490(-) (agrA) [Staphylococcus aureus isolate 24117-REV]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VRNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1150441 DYY93_RS10750 WP_115657841.1 2113774..2114490(-) (agrA) [Staphylococcus aureus isolate 24117-REV]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTCGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992

Multiple sequence alignment