Detailed information NTG1149891

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DXE26_RS00830
• Genome accession: NZ_LT992472
• Coordinates: 128480..129523 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus isolate 10_5235
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 123480..134523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DXE26_RS00800	-	123901..125157 (-)	1257	WP_074347694.1	aminopeptidase	-
DXE26_RS00805	-	125160..125360 (-)	201	WP_000180460.1	DUF1128 family protein	-
DXE26_RS00810	-	125507..125971 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
DXE26_RS00815	-	125978..126253 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
DXE26_RS00820	-	126531..127748 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
DXE26_RS00825	vraR	127861..128490 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
DXE26_RS00830	vraS	128480..129523 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
DXE26_RS00835	liaF	129520..130221 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
DXE26_RS00840	-	130236..130622 (-)	387	WP_001110182.1	hypothetical protein	-
DXE26_RS00845	map	130839..131597 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
DXE26_RS00855	-	132181..133167 (+)	987	WP_000999712.1	FUSC family protein	-
DXE26_RS00860	-	133356..133769 (-)	414	WP_025174370.1	hypothetical protein	-
DXE26_RS00865	-	133798..133908 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1149891 DXE26_RS00830 WP_001017131.1 128480..129523(-) (vraS) [Staphylococcus aureus isolate 10_5235]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1149891 DXE26_RS00830 WP_001017131.1 128480..129523(-) (vraS) [Staphylococcus aureus isolate 10_5235]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1