Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DXE65_RS09750 Genome accession   NZ_LT992462
Coordinates   1818856..1819572 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate 5_3949     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1813856..1824572
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE65_RS09720 - 1814123..1814749 (+) 627 WP_000522384.1 nitroreductase family protein -
  DXE65_RS09725 - 1815057..1815842 (+) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  DXE65_RS15970 hld 1816444..1816524 (-) 81 WP_000046022.1 delta-hemolysin -
  DXE65_RS09735 agrB 1816814..1817383 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  DXE65_RS09740 agrD 1817380..1817520 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  DXE65_RS09745 agrC 1817545..1818837 (+) 1293 WP_001825886.1 quorum-sensing sensor histidine kinase AgrC -
  DXE65_RS09750 agrA 1818856..1819572 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  DXE65_RS09755 - 1819946..1820905 (-) 960 WP_001253294.1 carbohydrate kinase family protein -
  DXE65_RS09760 - 1820902..1822386 (-) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  DXE65_RS09765 - 1822535..1823485 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1149481 DXE65_RS09750 WP_000688492.1 1818856..1819572(+) (agrA) [Staphylococcus aureus isolate 5_3949]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1149481 DXE65_RS09750 WP_000688492.1 1818856..1819572(+) (agrA) [Staphylococcus aureus isolate 5_3949]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment