Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DXE39_RS08735 Genome accession   NZ_LT992460
Coordinates   1687644..1688360 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate 9_LA_281     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1682644..1693360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE39_RS08720 - 1683731..1684681 (+) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -
  DXE39_RS08725 - 1684830..1686314 (+) 1485 WP_000141407.1 sucrose-6-phosphate hydrolase -
  DXE39_RS08730 - 1686311..1687270 (+) 960 WP_001253294.1 carbohydrate kinase family protein -
  DXE39_RS08735 agrA 1687644..1688360 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  DXE39_RS15140 agrC 1688379..1689672 (-) 1294 Protein_1645 quorum-sensing sensor histidine kinase AgrC -
  DXE39_RS08745 agrD 1689697..1689837 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  DXE39_RS08750 agrB 1689834..1690403 (-) 570 WP_001105708.1 accessory gene regulator AgrB -
  DXE39_RS15540 hld 1690693..1690773 (+) 81 WP_000046022.1 delta-hemolysin -
  DXE39_RS08760 - 1691375..1692160 (-) 786 WP_000867947.1 carbon-nitrogen family hydrolase -
  DXE39_RS08765 - 1692468..1693094 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1149369 DXE39_RS08735 WP_000688492.1 1687644..1688360(-) (agrA) [Staphylococcus aureus isolate 9_LA_281]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1149369 DXE39_RS08735 WP_000688492.1 1687644..1688360(-) (agrA) [Staphylococcus aureus isolate 9_LA_281]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment