Detailed information NTG1149292

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DXE58_RS11135
• Genome accession: NZ_LT992456
• Coordinates: 2171054..2172097 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus isolate 1_1439
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2166054..2177097

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DXE58_RS11100	-	2166669..2166779 (+)	111	WP_014937049.1	hypothetical protein	-
DXE58_RS11105	-	2166808..2167221 (+)	414	WP_025174370.1	hypothetical protein	-
DXE58_RS11110	-	2167410..2168396 (-)	987	WP_000999712.1	FUSC family protein	-
DXE58_RS11120	map	2168980..2169738 (+)	759	WP_000636145.1	type I methionyl aminopeptidase	-
DXE58_RS11125	-	2169955..2170341 (+)	387	WP_001110182.1	hypothetical protein	-
DXE58_RS11130	liaF	2170356..2171057 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
DXE58_RS11135	vraS	2171054..2172097 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
DXE58_RS11140	vraR	2172087..2172716 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
DXE58_RS11145	-	2172829..2174046 (-)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
DXE58_RS11150	-	2174324..2174599 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
DXE58_RS11155	-	2174606..2175070 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
DXE58_RS11160	-	2175217..2175417 (+)	201	WP_000180460.1	DUF1128 family protein	-
DXE58_RS11165	-	2175420..2176676 (+)	1257	WP_074347694.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1149292 DXE58_RS11135 WP_001017131.1 2171054..2172097(+) (vraS) [Staphylococcus aureus isolate 1_1439]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1149292 DXE58_RS11135 WP_001017131.1 2171054..2172097(+) (vraS) [Staphylococcus aureus isolate 1_1439]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1