Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DYY98_RS05475 Genome accession   NZ_LT992436
Coordinates   1043834..1044550 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus isolate 1549-REV     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1038834..1049550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYY98_RS05445 - 1039049..1039675 (+) 627 WP_076686081.1 nitroreductase family protein -
  DYY98_RS05450 - 1040036..1040821 (+) 786 WP_000867944.1 carbon-nitrogen family hydrolase -
  DYY98_RS14190 hld 1041422..1041502 (-) 81 WP_000046022.1 delta-hemolysin -
  DYY98_RS05460 agrB 1041792..1042361 (+) 570 WP_001105708.1 accessory gene regulator AgrB -
  DYY98_RS05465 agrD 1042358..1042498 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  DYY98_RS05470 agrC 1042523..1043815 (+) 1293 WP_172460476.1 quorum-sensing sensor histidine kinase AgrC -
  DYY98_RS05475 agrA 1043834..1044550 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  DYY98_RS05480 - 1044622..1044729 (+) 108 WP_031785433.1 hypothetical protein -
  DYY98_RS05485 - 1044919..1045878 (-) 960 WP_001253295.1 carbohydrate kinase family protein -
  DYY98_RS05490 - 1045875..1047359 (-) 1485 WP_000141419.1 sucrose-6-phosphate hydrolase -
  DYY98_RS05495 - 1047508..1048458 (-) 951 WP_000790314.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1149251 DYY98_RS05475 WP_000688492.1 1043834..1044550(+) (agrA) [Staphylococcus aureus isolate 1549-REV]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1149251 DYY98_RS05475 WP_000688492.1 1043834..1044550(+) (agrA) [Staphylococcus aureus isolate 1549-REV]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAGGATGATCCAGCAGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCTGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAGTCACACAGACTCATTGCGCATTTAGACAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGCTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATTG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment