Detailed information NTG1149214

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: DYY96_RS08670
• Genome accession: NZ_LT992435
• Coordinates: 1651728..1652393 (-)
• Length: 221 a.a.
• NCBI ID: WP_000697883.1
• Uniprot ID: A0A5F0HLH2
• Organism: Staphylococcus aureus isolate 1549-SCV
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1646728..1657393

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYY96_RS08650	-	1647182..1647295 (-)	114	WP_072468803.1	hypothetical protein	-
DYY96_RS08655	-	1647970..1649970 (-)	2001	WP_000776737.1	ABC transporter permease	-
DYY96_RS08660	-	1649967..1650722 (-)	756	WP_000923765.1	ABC transporter ATP-binding protein	-
DYY96_RS08665	nsaS	1650830..1651717 (-)	888	Protein_1614	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	-
DYY96_RS08670	braR	1651728..1652393 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DYY96_RS08675	-	1652419..1652619 (-)	201	WP_000604722.1	hypothetical protein	-
DYY96_RS08680	-	1652817..1654241 (+)	1425	WP_000953745.1	alkaline phosphatase	-
DYY96_RS14210	-	1654301..1654402 (-)	102	WP_000731972.1	SE2200 family small protein	-
DYY96_RS08690	-	1654524..1654979 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DYY96_RS08695	-	1655219..1655980 (-)	762	WP_000323450.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 25433.52 Da
• Isoelectric Point: 4.7961

>NTDB_id=1149214 DYY96_RS08670 WP_000697883.1 1651728..1652393(-) (braR) [Staphylococcus aureus isolate 1549-SCV]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide

• Length: 666 bp

>NTDB_id=1149214 DYY96_RS08670 WP_000697883.1 1651728..1652393(-) (braR) [Staphylococcus aureus isolate 1549-SCV]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGTCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-220)

• Response regulator receiver domain (Response_reg) (3-111)

3D structure

• AlphaFold DB: A0A5F0HLH2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	99.548	100	0.995