Detailed information NTG1149208

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DYY96_RS04755
• Genome accession: NZ_LT992435
• Coordinates: 927775..928818 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus isolate 1549-SCV
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 922775..933818

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DYY96_RS04725	-	923196..924443 (-)	1248	WP_000656302.1	aminopeptidase	-
DYY96_RS04730	-	924455..924655 (-)	201	WP_000180459.1	DUF1128 family protein	-
DYY96_RS04735	-	924802..925266 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
DYY96_RS04740	-	925273..925548 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
DYY96_RS04745	-	925826..927043 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
DYY96_RS04750	vraR	927156..927785 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
DYY96_RS04755	vraS	927775..928818 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
DYY96_RS04760	liaF	928815..929516 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
DYY96_RS04765	-	929531..929917 (-)	387	WP_001110184.1	hypothetical protein	-
DYY96_RS04770	map	930134..930892 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
DYY96_RS04780	-	931479..932465 (+)	987	WP_000999713.1	FUSC family protein	-
DYY96_RS04785	-	932643..933056 (-)	414	WP_001622129.1	hypothetical protein	-
DYY96_RS04790	-	933085..933194 (-)	110	Protein_881	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1149208 DYY96_RS04755 WP_001017131.1 927775..928818(-) (vraS) [Staphylococcus aureus isolate 1549-SCV]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1149208 DYY96_RS04755 WP_001017131.1 927775..928818(-) (vraS) [Staphylococcus aureus isolate 1549-SCV]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1