Detailed information NTG1148900

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DG022_RS04425
• Genome accession: NZ_LT963436
• Coordinates: 915579..916622 (+)
• Length: 347 a.a.
• NCBI ID: WP_011302781.1
• Uniprot ID: -
• Organism: Staphylococcus saprophyticus isolate Staphylococcus saprophyticus 883
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 910579..921622

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DG022_RS04395	-	911287..911592 (+)	306	WP_064205823.1	helix-turn-helix domain-containing protein	-
DG022_RS04400	-	911598..912383 (+)	786	WP_231912204.1	IS3 family transposase	-
DG022_RS04405	-	912461..913447 (-)	987	WP_069827396.1	FUSC family protein	-
DG022_RS04410	map	913622..914374 (+)	753	WP_011302778.1	type I methionyl aminopeptidase	-
DG022_RS04415	-	914478..914864 (+)	387	WP_047504955.1	hypothetical protein	-
DG022_RS04420	liaF	914881..915582 (+)	702	WP_011302780.1	cell wall-active antibiotics response protein LiaF	-
DG022_RS04425	vraS	915579..916622 (+)	1044	WP_011302781.1	sensor histidine kinase	Regulator
DG022_RS04430	vraR	916612..917241 (+)	630	WP_002482846.1	response regulator transcription factor	Regulator
DG022_RS04435	-	917398..918570 (-)	1173	WP_069794960.1	YihY/virulence factor BrkB family protein	-
DG022_RS04440	-	918982..919266 (-)	285	WP_002482848.1	hypothetical protein	-
DG022_RS04445	-	919273..919737 (-)	465	WP_011302783.1	low molecular weight protein-tyrosine-phosphatase	-
DG022_RS04450	-	919872..920075 (+)	204	WP_002482850.1	DUF1128 family protein	-
DG022_RS04455	-	920089..921327 (+)	1239	WP_011302784.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40050.55 Da
• Isoelectric Point: 6.4221

>NTDB_id=1148900 DG022_RS04425 WP_011302781.1 915579..916622(+) (vraS) [Staphylococcus saprophyticus isolate Staphylococcus saprophyticus 883]
MNHYFRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSNAD

Nucleotide

• Length: 1044 bp

>NTDB_id=1148900 DG022_RS04425 WP_011302781.1 915579..916622(+) (vraS) [Staphylococcus saprophyticus isolate Staphylococcus saprophyticus 883]
ATGAATCACTACTTTAGAGCGATCGGGTCCATGTTGATATTAGTATATAGTACGTTTTTTGCCATATTCTTTATTGATAA
AGTGTTTGTTAATATAATGTATTTTCAAGGTATGTTTTATACTCAAATATTTGGCATACCTGTACTGCTTTTTTTAAATC
TAATGGTGATTTTACTCTGTATTATTGTAGGTTCTGTCTTAGCATATAAAATCAATCAGCAAAATCATTGGTTAAAAGAT
CAAATTGAACGTTCAATAGAAGGTCAAACAGTGGGTATCAATGATCAAAATATTGAATTATACAACGAAACAATCGAACT
ATATCAAACGCTTGTGCCTTTAAATCAAGAAGTACATAAATTAAGAATGAAAACACAGAACCTGACGAATGAATCTTATA
ATATCAATGATGTTAAAGTTAAGAAAATTATAGAAGACGAACGCCAACGTTTAGCGCGTGAATTACATGATTCAGTTAGT
CAACAATTATTCGCAGCAAGTATGATGTTATCAGCAATTAAAGAGACAGAATTGAAGGCCCCATTGGACCAACAAATACC
AGTATTAGAAAAAATGATTCAAGATTCCCAATTAGAAATGAGAGCACTACTATTACACTTAAGACCTATTGGTTTGAAAG
ATAAATCTTTAGGTGAGGGTATTAAAGATTTAGTCGTTGATTTACAGAAAAAAGTACCAATGAAAGTGGTACATGATATT
GAAGAATTCAAAGTACCAAAAGGTATCGAGGACCATTTATTCCGTATTACGCAAGAAGCCATTTCTAATACGCTAAGACA
TTCTAAAGGAACGAAGGTCACAATTGAATTATTTAATAGGGAAGAATATTTGTTATTGCGTATACAAGATAATGGTAAAG
GGTTTAATGTAGATGATAAGGTAGAACAAAGTTATGGATTAAAAAATATGCGCGAACGTGCACTAGAAATAGGTGCAACA
TTTCATATAGTTTCTTTGCCTGATGCAGGTACGAGAATTGAAGTGAAGGCACCATTAAATAAGGAGGATTCAAATGCCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	87.32	100	0.873