Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CKV88_RS09195 Genome accession   NZ_LT906460
Coordinates   1969746..1970462 (+) Length   238 a.a.
NCBI ID   WP_002464787.1    Uniprot ID   G5JKT5
Organism   Staphylococcus simiae strain NCTC13838     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1964746..1975462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV88_RS09165 (SAMEA4384339_01868) - 1965364..1965990 (+) 627 WP_002464793.1 nitroreductase family protein -
  CKV88_RS09170 (SAMEA4384339_01869) - 1966218..1967003 (+) 786 WP_002464792.1 carbon-nitrogen family hydrolase -
  CKV88_RS09175 hld 1967345..1967422 (-) 78 WP_002464791.1 delta-hemolysin -
  CKV88_RS09180 (SAMEA4384339_01871) - 1967715..1968281 (+) 567 WP_002464790.1 accessory gene regulator AgrB -
  CKV88_RS09185 (SAMEA4384339_01872) agrD 1968281..1968421 (+) 141 WP_002464789.1 cyclic lactone autoinducer peptide AgrD -
  CKV88_RS09190 (SAMEA4384339_01873) agrC 1968444..1969733 (+) 1290 WP_002464788.1 quorum-sensing sensor histidine kinase AgrC -
  CKV88_RS09195 (SAMEA4384339_01874) agrA 1969746..1970462 (+) 717 WP_002464787.1 quorum-sensing response regulator AgrA Regulator
  CKV88_RS09200 (SAMEA4384339_01875) - 1970578..1971531 (-) 954 WP_002464786.1 carbohydrate kinase -
  CKV88_RS09205 (SAMEA4384339_01876) - 1971531..1973012 (-) 1482 WP_002464785.1 sucrose-6-phosphate hydrolase -
  CKV88_RS09210 (SAMEA4384339_01877) - 1973160..1974110 (-) 951 WP_002464784.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27888.91 Da        Isoelectric Point: 6.0381

>NTDB_id=1147651 CKV88_RS09195 WP_002464787.1 1969746..1970462(+) (agrA) [Staphylococcus simiae strain NCTC13838]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDDPYEVLEHSKNMTDIGCYFLDIQLASDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELKTRIIDCLETAHTRLQLLSKESNVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNIKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1147651 CKV88_RS09195 WP_002464787.1 1969746..1970462(+) (agrA) [Staphylococcus simiae strain NCTC13838]
ATGAAAATTTTCATTTGTGAAGATGACCCAAAACAACGAGAAAATATGGTAACAATTATTAAGAATTACATTATGATAGA
AGAAAAACCAATGGAAATTGCTCTGGCAACTGATGATCCTTATGAAGTACTTGAACATTCTAAAAATATGACAGATATTG
GTTGCTACTTTTTAGATATACAATTAGCCTCTGATATTAACGGTATCAAATTAGGTAGTGAAATACGTAAACATGATCCC
GTTGGTAATATTATCTTTGTTACTAGTCATAGTGAACTAACTTATCTTACTTTTGTCTATAAAGTGGCTGCCATGGACTT
TATCTTTAAAGATGACCCTGCAGAGTTAAAAACTAGAATTATTGATTGCCTTGAAACTGCGCATACGAGATTACAATTAT
TATCTAAAGAAAGTAACGTTGAAACAATCGAACTTAAGCGTGGTAGTAATTCTGTTTATGTTCAATATGATGATATTATG
TTCTTCGAATCATCGACGAAATCTCATCGCTTAATTGCACATTTAGATAATCGTCAAATTGAATTTTATGGTAATTTAAA
AGAATTGAGTCAATTAGATGATCGTTTCTTCCGATGTCACAATAGTTTCGTTGTCAATCGTCACAACATTGAATCTATAG
ACTCTAAAGAACGTATCGTTTACTTCAAAAATAAAGAACATTGTTATGCTTCAGTGCGAAATATTAAAAAAATATAG

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JKT5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

95.378

100

0.954

Multiple sequence alignment