Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   CKV83_RS09435 Genome accession   NZ_LT906439
Coordinates   2012653..2013366 (+) Length   237 a.a.
NCBI ID   WP_018374048.1    Uniprot ID   A0A239SY95
Organism   Streptococcus merionis strain NCTC13788     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2007653..2018366
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV83_RS09420 (SAMEA4412692_01879) spx 2008068..2008466 (+) 399 WP_018374051.1 transcriptional regulator Spx -
  CKV83_RS09425 (SAMEA4412692_01880) treC 2008870..2010504 (-) 1635 WP_018374050.1 alpha,alpha-phosphotrehalase -
  CKV83_RS09430 (SAMEA4412692_01881) treP 2010983..2012458 (-) 1476 Protein_1811 PTS system trehalose-specific EIIBC component -
  CKV83_RS09435 (SAMEA4412692_01882) treR 2012653..2013366 (+) 714 WP_018374048.1 trehalose operon repressor Regulator
  CKV83_RS09440 (SAMEA4412692_01883) - 2013377..2013844 (+) 468 WP_018374047.1 GNAT family N-acetyltransferase -
  CKV83_RS09445 (SAMEA4412692_01884) glnA 2013884..2015230 (-) 1347 WP_018374046.1 type I glutamate--ammonia ligase -
  CKV83_RS09450 (SAMEA4412692_01885) - 2015261..2015623 (-) 363 WP_018374045.1 MerR family transcriptional regulator -
  CKV83_RS09455 (SAMEA4412692_01886) - 2015696..2016217 (-) 522 WP_018374044.1 aromatic acid exporter family protein -
  CKV83_RS09460 (SAMEA4412692_01887) - 2016493..2016948 (-) 456 WP_018374043.1 hypothetical protein -
  CKV83_RS09465 (SAMEA4412692_01888) - 2016962..2017174 (-) 213 WP_018374042.1 helix-turn-helix transcriptional regulator -
  CKV83_RS09470 (SAMEA4412692_01889) - 2017177..2017689 (-) 513 WP_018374041.1 DUF2975 domain-containing protein -
  CKV83_RS09475 (SAMEA4412692_01890) - 2017911..2018090 (+) 180 Protein_1820 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27392.18 Da        Isoelectric Point: 6.7685

>NTDB_id=1147152 CKV83_RS09435 WP_018374048.1 2012653..2013366(+) (treR) [Streptococcus merionis strain NCTC13788]
MKKYQEIFNDLRDRITKGHYAPDELLPTEQNLRKIYDVSRDTVRKALSLLTEAGLIQKIQGRGSVVIKQEQVDFPVSGLT
SYQELVETQGLHSKTEVISFELLTIDSHLALLTGFKQHSKAWKVVRTRALDGKVAVLDTDYLSYDFAPQLSQEIAAKSIY
AYLEDDLQLDISYAQKEITVEPSSQEERELMQNKDDFLVLIKSRVFLGNAQQFQYTESRHKLDKFKFVEFARRKHSL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=1147152 CKV83_RS09435 WP_018374048.1 2012653..2013366(+) (treR) [Streptococcus merionis strain NCTC13788]
ATGAAAAAATATCAAGAAATTTTCAACGATTTAAGAGACAGAATCACTAAAGGTCATTATGCACCTGATGAGCTCCTACC
AACTGAGCAAAATCTTCGCAAAATATACGACGTCAGTCGTGACACTGTTCGAAAAGCTTTGAGCCTGCTGACAGAGGCTG
GACTAATCCAAAAAATCCAAGGACGTGGCTCTGTTGTCATCAAGCAAGAACAGGTTGATTTCCCCGTATCGGGCCTGACT
TCCTATCAAGAGTTGGTCGAAACACAAGGGCTTCATTCTAAGACAGAAGTCATCTCCTTTGAGCTCTTGACCATCGATAG
CCATTTAGCACTCTTAACTGGCTTTAAACAACATAGTAAGGCTTGGAAAGTCGTCCGCACAAGGGCGTTAGATGGTAAAG
TAGCTGTTCTTGATACAGACTACCTGTCCTATGACTTTGCACCGCAGCTAAGTCAGGAAATTGCAGCCAAGTCTATCTAT
GCCTACCTAGAAGATGATCTCCAACTGGACATTTCATACGCCCAGAAGGAAATTACTGTCGAGCCTAGCAGTCAAGAAGA
ACGGGAATTGATGCAAAATAAAGATGATTTCCTTGTCTTGATTAAATCTCGCGTTTTCTTGGGCAACGCGCAACAGTTTC
AATATACTGAAAGCCGTCATAAACTGGACAAGTTCAAGTTTGTTGAATTTGCTCGTCGAAAGCACAGTCTATAA

Domains

Predicted by InterproScan.

UTRA domain (UTRA)

(89-226)

Bacterial regulatory proteins, gntR family (GntR)

(3-66)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239SY95

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

52.137

98.734

0.515

Multiple sequence alignment