Detailed information NTG1147114

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: CKV83_RS00285
• Genome accession: NZ_LT906439
• Coordinates: 58335..60575 (-)
• Length: 746 a.a.
• NCBI ID: WP_026216877.1
• Uniprot ID: A0A239SMR5
• Organism: Streptococcus merionis strain NCTC13788
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 53335..65575

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKV83_RS00270 (SAMEA4412692_00056)	ileS	53650..56442 (+)	2793	WP_018372951.1	isoleucine--tRNA ligase	-
CKV83_RS00275 (SAMEA4412692_00057)	-	56817..57119 (-)	303	WP_018372952.1	DUF1827 family protein	-
CKV83_RS00280 (SAMEA4412692_00058)	-	57160..57621 (-)	462	WP_018372953.1	NUDIX hydrolase	-
CKV83_RS00285 (SAMEA4412692_00059)	clpE	58335..60575 (-)	2241	WP_026216877.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
CKV83_RS00290 (SAMEA4412692_00060)	-	61041..61271 (+)	231	WP_018372955.1	DUF1797 family protein	-
CKV83_RS00295 (SAMEA4412692_00061)	-	61344..62057 (-)	714	WP_018372956.1	B3/4 domain-containing protein	-
CKV83_RS00300 (SAMEA4412692_00062)	-	62529..63389 (+)	861	WP_026216878.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
CKV83_RS00305 (SAMEA4412692_00063)	-	63429..63815 (+)	387	WP_018372958.1	GNAT family N-acetyltransferase	-
CKV83_RS00310 (SAMEA4412692_00064)	-	63790..64644 (+)	855	WP_018372959.1	NAD(P)H-hydrate dehydratase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 83515.50 Da
• Isoelectric Point: 5.0215

>NTDB_id=1147114 CKV83_RS00285 WP_026216877.1 58335..60575(-) (clpE) [Streptococcus merionis strain NCTC13788]
MLCHNCKMNDATIHLYSNYNGRQQQVDLCQNCYQIMKTDPENPILRGLSQIQNQQRSPFDDFFDNLSNFQHPSQAPGNQI
PPTQAGRNNSNRGGNQQPPKKGLLDEFGINVTEIARRGGIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEPGVGKTAVVE
GLAQKIVDADVPHKLQNKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRERQDVILFIDEIHEIVGAGSAGDGNMDAGN
ILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVRVDEPSVEETITILKGIQKRYEDYHHVRYTDEAIEAAANLSN
RYIQDRFLPDKAIDLLDESGSKMNLTLNFVDPKEIDQRLVEAENLKAQATRDEDYEKAAYFRDQIAKYKEMQKATLDEKD
IPVITEKEIEAIVERKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPT
GVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSTAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEIEKAHPDVM
HMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVLGQLGDFFSPEFMNRFDGIIEFQAL
SKDNLLQIVDLMLNNVNDRLANNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPTEKDLRAVM
TSSGNIAIKPAKKTEKTNTTDEETDQ

Nucleotide

• Length: 2241 bp

>NTDB_id=1147114 CKV83_RS00285 WP_026216877.1 58335..60575(-) (clpE) [Streptococcus merionis strain NCTC13788]
ATGCTTTGTCATAATTGTAAAATGAACGACGCAACCATTCACCTGTATAGCAATTACAATGGTCGCCAACAACAGGTTGA
CCTCTGTCAAAACTGCTACCAAATCATGAAAACTGACCCAGAAAATCCTATTTTAAGAGGATTATCTCAAATTCAAAACC
AACAAAGAAGCCCGTTTGATGACTTCTTTGATAATTTGAGCAATTTCCAACATCCAAGTCAAGCTCCTGGAAATCAAATT
CCACCAACTCAAGCTGGCCGAAACAACAGTAACCGTGGTGGCAATCAACAACCGCCTAAAAAGGGACTTTTGGACGAATT
TGGTATTAATGTGACCGAAATCGCTCGCCGTGGCGGCATTGACCCTGTCATCGGTCGTGATGAGGAGATTGTTCGCGTCA
TTGAAATCCTCAATCGTCGTACCAAGAACAACCCTGTTCTAATCGGAGAGCCTGGTGTTGGTAAGACAGCTGTCGTTGAA
GGCTTAGCTCAAAAGATCGTTGATGCTGATGTACCACATAAGTTGCAAAACAAGCAGGTCATCCGTCTTGATGTCGTCAG
TCTCGTCCAAGGCACCGGTATCCGTGGTCAATTTGAAGAGCGCATGCAAAAGTTGATGGAAGAAATCCGTGAGCGTCAAG
ATGTCATTCTCTTCATCGATGAAATTCACGAGATTGTCGGAGCAGGTAGCGCTGGCGATGGCAATATGGATGCAGGCAAC
ATCCTAAAACCAGCTCTAGCTCGTGGAGAGCTCCAACTGGTCGGCGCGACCACTCTCAACGAATACCGCATTATCGAAAA
GGATGCGGCTCTGGAGCGTCGCATGCAGCCAGTCCGTGTCGATGAACCAAGTGTAGAAGAGACCATTACGATCTTAAAAG
GCATCCAAAAACGCTACGAAGATTACCACCATGTGCGCTACACCGATGAAGCCATCGAAGCTGCCGCTAATCTGTCTAAC
CGTTATATTCAAGACCGCTTCTTGCCAGACAAGGCTATTGACCTTCTGGATGAGTCAGGCTCCAAGATGAATTTGACCCT
CAATTTTGTGGATCCTAAAGAAATTGATCAACGTTTGGTTGAGGCTGAAAACCTCAAAGCTCAAGCTACTCGTGATGAAG
ATTACGAAAAAGCTGCTTATTTCCGCGATCAGATTGCCAAATACAAAGAAATGCAGAAGGCCACCCTTGATGAGAAAGAC
ATTCCTGTCATTACCGAAAAAGAAATTGAAGCAATAGTTGAGCGCAAAACCAATATCCCTGTCGGAGATCTCAAAGAAAA
AGAGCAGAGTCAACTTGTCAACCTTGCGAGCGACCTTAAAGCCCATGTCATTGGTCAAGATGAAGCAGTTGATAAGATTG
CCAAAGCCATTCGGCGCAACCGTGTCGGACTTGGTGCTCCAAACCGTCCAATCGGCTCCTTCCTTTTTGTCGGCCCAACA
GGTGTCGGTAAAACAGAGTTATCGAAACAGTTAGCCATTGAACTCTTCGGCTCAGCGGATAGCATGATTCGTTTTGACAT
GTCTGAATATATGGAAAAACACAGCACAGCCAAATTGGTCGGTGCTCCTCCAGGTTATGTTGGCTATGACGAAGCTGGAC
AACTGACCGAGAAAGTCCGCCGCAATCCTTACTCACTCATTCTTCTTGATGAAATTGAAAAAGCGCACCCTGATGTCATG
CACATGTTCCTTCAGGTTCTAGATGATGGCCGCTTAACCGATGGCCAAGGCCGCACAGTCAGCTTCAAAGACACCATTAT
CATCATGACGTCAAATGCCGGTACTGGTAAGGTCGAAGCCTCTGTTGGCTTTGGTGCAGCCAGAGAAAATCGGACGAACT
CTGTTCTTGGTCAGCTGGGCGACTTCTTCAGCCCAGAATTCATGAACCGATTTGACGGTATCATCGAATTTCAAGCTCTC
AGCAAAGACAATCTTCTCCAAATCGTTGATCTCATGCTTAACAACGTTAACGATCGTCTTGCTAACAACGGCATCAGCTT
ACACGTGACCGATAAGGTCAAGGAAAAGCTGGTTGATCTGGGCTATGATCCGAAAATGGGAGCTCGTCCTCTCCGCCGAA
CTATCCAAGATCATATTGAAGACGCCATCACGGACTTCTATCTAGAAAATCCAACCGAAAAAGACCTCCGAGCAGTTATG
ACCTCATCAGGCAACATTGCGATAAAGCCTGCTAAAAAAACTGAAAAAACCAACACAACTGATGAGGAGACCGACCAATA
G

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (640-714)

• AAA domain (Cdc48 subfamily) (AAA_2) (469-632)

• ATPase family associated with various cellular activities (AAA) (AAA) (146-266)

• AAA lid domain (AAA_lid_9) (284-381)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	83.624	99.866	0.835
clpE	Streptococcus pneumoniae D39	82.361	100	0.832
clpE	Streptococcus pneumoniae R6	82.361	100	0.832
clpE	Streptococcus pneumoniae Rx1	82.361	100	0.832
clpE	Streptococcus pneumoniae TIGR4	82.361	100	0.832
clpC	Lactococcus lactis subsp. cremoris KW2	76.064	100	0.767
clpC	Bacillus subtilis subsp. subtilis str. 168	52.148	90.483	0.472
clpC	Streptococcus pneumoniae D39	48.206	85.925	0.414
clpC	Streptococcus pneumoniae Rx1	48.206	85.925	0.414
clpC	Streptococcus pneumoniae TIGR4	48.05	85.925	0.413
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.84	83.78	0.401
clpC	Streptococcus thermophilus LMD-9	46.855	85.255	0.399
clpC	Streptococcus mutans UA159	46.688	84.987	0.397
clpC	Streptococcus thermophilus LMG 18311	46.541	85.255	0.397