Detailed information NTG1146411

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: CS885_RS07815
• Genome accession: NZ_LT838273
• Coordinates: 1585007..1586212 (-)
• Length: 401 a.a.
• NCBI ID: WP_089086745.1
• Uniprot ID: A0A238GUL3
• Organism: Helicobacter pylori isolate HE93/10_v1
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1580007..1591212

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CS885_RS07790	-	1580448..1580675 (-)	228	Protein_1479	replication regulatory RepB family protein	-
CS885_RS07795	-	1580645..1581529 (-)	885	WP_089086741.1	ATPase, T2SS/T4P/T4SS family	-
CS885_RS07800	-	1581534..1581809 (-)	276	WP_089086742.1	hypothetical protein	-
CS885_RS07805	-	1581826..1582788 (-)	963	WP_089086743.1	hypothetical protein	-
CS885_RS07810	-	1582801..1585023 (-)	2223	WP_089086744.1	RGS domain-containing GTPase-activating protein	-
CS885_RS07815	comB10	1585007..1586212 (-)	1206	WP_089086745.1	DNA type IV secretion system protein ComB10	Machinery gene
CS885_RS07820	-	1586209..1587864 (-)	1656	WP_000617227.1	TrbG/VirB9 family P-type conjugative transfer protein	-
CS885_RS07825	-	1587861..1588997 (-)	1137	WP_089086746.1	VirB8/TrbF family protein	-
CS885_RS08665	-	1588990..1589130 (-)	141	WP_000789928.1	hypothetical protein	-

Sequence

Protein

• Length: 401 a.a.
• Molecular weight: 44905.59 Da
• Isoelectric Point: 10.1066

>NTDB_id=1146411 CS885_RS07815 WP_089086745.1 1585007..1586212(-) (comB10) [Helicobacter pylori isolate HE93/10_v1]
MKQSLLKKIGLGVGGFVVLMALGLLANKGSNNNNKEEIFQVSESKFPLSDYFFEEVKEEPKKAKETPEVTTQEPTTQTSP
NPSVSANPNIKDYSHLNNNLNQQNNTITHLQQVLQSPSKIKPKPKHTKEQLEFLNTRLKPLEPTKPATKPEMEYGVDSFT
NLKYKDIGTNEHKLLRTITADRMIPAFLITPISSQIAGKVTAQVESDIFASMGRAVLIPKGSKVIGYYNNNNQIGQYRLN
IAWTRIITPQGINIMLTNARGADVKGYNGLVGKYISRNFQRYGIPLLTNTLSNGLLIGITSALANRQNRKGDGNPFFGDY
LLMQLTRNTGMGINQVINQMLRQYGAQNPIIIIREGSRVFISPNLDIFIPKPKDGEVLAEFFKEKKPLIKTKEEINNEEE
I

Nucleotide

• Length: 1206 bp

>NTDB_id=1146411 CS885_RS07815 WP_089086745.1 1585007..1586212(-) (comB10) [Helicobacter pylori isolate HE93/10_v1]
ATGAAACAATCCTTGCTTAAAAAGATAGGCTTAGGTGTTGGGGGCTTTGTTGTTTTAATGGCATTAGGATTGCTTGCTAA
TAAAGGCTCAAACAATAACAATAAAGAAGAAATCTTTCAAGTAAGTGAGAGTAAATTCCCTTTAAGTGATTATTTCTTTG
AAGAAGTCAAAGAAGAGCCAAAAAAAGCCAAAGAAACACCAGAAGTAACTACCCAAGAGCCTACAACACAAACTAGCCCC
AATCCTAGTGTTTCAGCTAATCCTAACATTAAAGATTATAGTCATCTTAACAACAATCTTAATCAGCAAAATAATACTAT
CACGCATTTACAACAAGTTTTACAAAGCCCCTCTAAAATAAAGCCTAAACCAAAGCATACTAAAGAGCAATTAGAATTTT
TAAACACACGCCTTAAACCTTTAGAACCAACTAAACCAGCCACTAAGCCTGAGATGGAATACGGCGTGGATAGTTTTACT
AATTTAAAATATAAAGACATCGGCACTAATGAGCATAAGCTTTTAAGAACCATAACCGCTGATAGAATGATACCAGCCTT
TTTAATCACGCCTATTAGCTCTCAAATTGCTGGAAAAGTAACCGCCCAAGTAGAGAGCGATATATTTGCTTCTATGGGTA
GAGCGGTGCTAATCCCTAAAGGCTCTAAAGTTATAGGCTATTACAATAATAACAATCAAATTGGACAATACCGCCTTAAC
ATTGCTTGGACTAGAATTATCACGCCTCAAGGCATAAACATCATGCTCACTAACGCAAGGGGGGCTGATGTGAAGGGTTA
TAATGGCTTAGTAGGCAAATACATTAGCCGAAACTTTCAACGCTATGGTATCCCCTTACTCACTAACACGCTCTCTAATG
GTCTTTTAATAGGAATTACTTCAGCCTTAGCTAATAGGCAAAATAGAAAGGGTGATGGCAACCCTTTTTTTGGGGATTAC
TTGCTTATGCAACTCACTAGAAATACAGGCATGGGCATCAATCAAGTTATCAATCAAATGCTAAGGCAATATGGAGCGCA
AAACCCCATTATCATCATTAGAGAGGGGAGCAGAGTGTTTATTAGCCCTAATTTAGACATCTTTATCCCTAAACCAAAAG
ATGGGGAGGTTTTAGCGGAGTTCTTTAAAGAGAAAAAACCCCTAATCAAAACAAAAGAGGAAATTAACAATGAAGAAGAA
ATCTAA

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (177-367)

3D structure

• AlphaFold DB: A0A238GUL3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	52.821	97.257	0.514