Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   CS885_RS05445 Genome accession   NZ_LT838273
Coordinates   1103007..1103288 (+) Length   93 a.a.
NCBI ID   WP_001272686.1    Uniprot ID   G2MDJ3
Organism   Helicobacter pylori isolate HE93/10_v1     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1098007..1108288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CS885_RS05420 groES 1098571..1098927 (-) 357 WP_000671927.1 co-chaperone GroES -
  CS885_RS05430 dnaG 1099214..1100893 (+) 1680 WP_089086464.1 DNA primase -
  CS885_RS05435 - 1100890..1101942 (+) 1053 WP_089086465.1 MnmA/TRMU family protein -
  CS885_RS05440 - 1102035..1102862 (+) 828 WP_001154942.1 DUF5718 family protein -
  CS885_RS05445 comB2 1103007..1103288 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  CS885_RS05450 comB3 1103288..1103551 (+) 264 WP_000584948.1 hypothetical protein Machinery gene
  CS885_RS05455 comB4 1103553..1105919 (+) 2367 WP_089086466.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  CS885_RS05465 - 1106224..1107564 (+) 1341 WP_001876830.1 COG3014 family protein -

Sequence

Protein


Download         Length: 93 a.a.        Molecular weight: 10539.81 Da        Isoelectric Point: 9.1450

>NTDB_id=1146399 CS885_RS05445 WP_001272686.1 1103007..1103288(+) (comB2) [Helicobacter pylori isolate HE93/10_v1]
MSAHFLKIIFLVGMCVSSLFAEGLEGFFNALEAQLKSPIAKGILMVIFIGIAIYVWRNLDRWKEILFTILGVVFGIFLFF
KAPSLANWFMGIF

Nucleotide


Download         Length: 282 bp        

>NTDB_id=1146399 CS885_RS05445 WP_001272686.1 1103007..1103288(+) (comB2) [Helicobacter pylori isolate HE93/10_v1]
ATGTCCGCTCATTTTTTGAAAATCATTTTTTTAGTAGGCATGTGCGTTTCAAGTTTGTTCGCTGAAGGATTAGAGGGGTT
TTTTAACGCCCTAGAAGCCCAGCTCAAAAGCCCCATCGCTAAGGGGATTTTAATGGTGATTTTCATAGGGATCGCCATTT
ATGTGTGGAGGAATTTGGACCGGTGGAAAGAGATCTTATTCACGATCCTTGGCGTGGTGTTTGGGATCTTCTTGTTCTTT
AAGGCCCCGAGTTTAGCGAATTGGTTTATGGGAATTTTTTAA

Domains

Predicted by InterproScan.

TrbC/VIRB2 pilin (TrbC)

(6-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G2MDJ3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

98.925

100

0.989

Multiple sequence alignment