Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/comE3   Type   Machinery gene
Locus tag   BCM300_RS06625 Genome accession   NZ_LT837687
Coordinates   1325273..1326586 (-) Length   437 a.a.
NCBI ID   WP_172825131.1    Uniprot ID   A0A238GWW9
Organism   Helicobacter pylori isolate BCM-300     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1320273..1331586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BCM300_RS06595 (BCM300_01298) nadC 1320736..1321557 (-) 822 WP_001918844.1 carboxylating nicotinate-nucleotide diphosphorylase -
  BCM300_RS06600 (BCM300_01299) nadA 1321557..1322567 (-) 1011 WP_001141844.1 quinolinate synthase NadA -
  BCM300_RS06605 (BCM300_01300) - 1322557..1323360 (-) 804 WP_089087185.1 phosphatidylserine decarboxylase -
  BCM300_RS06610 (BCM300_01301) - 1323354..1323860 (-) 507 WP_000953090.1 DUF6115 domain-containing protein -
  BCM300_RS06615 (BCM300_01302) - 1323873..1324367 (-) 495 WP_172825130.1 hypothetical protein -
  BCM300_RS06620 (BCM300_01303) mqnP 1324360..1325202 (-) 843 WP_231899378.1 menaquinone biosynthesis prenyltransferase MqnP -
  BCM300_RS06625 (BCM300_01304) comEC/comE3 1325273..1326586 (-) 1314 WP_172825131.1 ComEC/Rec2 family competence protein Machinery gene
  BCM300_RS06630 (BCM300_01305) - 1326583..1328043 (-) 1461 WP_089087188.1 replicative DNA helicase -
  BCM300_RS06635 (BCM300_01306) - 1328054..1329448 (-) 1395 WP_089087189.1 NAD(P)H-hydrate dehydratase -
  BCM300_RS06640 (BCM300_01307) crdS 1329451..1330653 (-) 1203 WP_089087190.1 copper-sensing histidine kinase CrdS -
  BCM300_RS06645 (BCM300_01308) crdR 1330619..1331260 (-) 642 WP_089087191.1 copper response regulator transcription factor CrdR -
  BCM300_RS06650 - 1331396..1331497 (-) 102 Protein_1257 anthranilate synthase component I -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 50064.86 Da        Isoelectric Point: 9.8459

>NTDB_id=1146342 BCM300_RS06625 WP_172825131.1 1325273..1326586(-) (comEC/comE3) [Helicobacter pylori isolate BCM-300]
MKDKTFQGAFELLATPKEYSWCGVVLSLLLVINLYLEYLNYQKLDFSKPTSLNAQILLQYPKTKDQKTYFVLKLQSKGMI
FYTTIKEPLKNLQYRHAHFFGKIKSCSFLESLKSCFFQTYSFSLMRKQDFKSHLRHFIDSAHSNALVGNLYRALFIGDSL
NKDLRDRANALGISHLLAISGFHLGILSASAYFLFSLFYTPLQKRYFPYRNAFYDIGVLVWVFLLGYLLLLDFLPSFFRA
FLMGLLGFLACFFGVRILSFKLLVLACCIAIALLPKLLFSVGFLLSVCGVWYIFLFLKHTQIFFKDSSFFKRSFQAIALS
VLVFLNMLIVAHAFFPMFSPYQLFSIPLGLIFIVFFPLSLFLHAVGLGSLLDSILSMPLTIPTISVSSPLWLLGAHLFLT
ILSARFFKVYLSMNVLSTGFFLYCCYQYIIMPSSIVG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=1146342 BCM300_RS06625 WP_172825131.1 1325273..1326586(-) (comEC/comE3) [Helicobacter pylori isolate BCM-300]
TTGAAAGATAAAACTTTTCAGGGGGCGTTTGAACTTCTTGCAACCCCCAAAGAATACTCATGGTGTGGGGTTGTTTTAAG
CCTTTTGTTGGTGATCAACCTTTATTTAGAATACTTGAATTACCAAAAGCTTGATTTTTCAAAACCTACAAGCCTGAACG
CTCAAATCTTATTACAATACCCTAAAACTAAAGATCAAAAAACCTATTTTGTCTTAAAGCTCCAATCTAAGGGCATGATC
TTTTACACCACCATTAAAGAGCCTTTAAAAAACCTCCAATACCGCCACGCGCATTTTTTTGGCAAGATCAAATCTTGCTC
GTTCTTAGAGTCTCTAAAATCATGCTTTTTTCAAACTTATTCTTTTTCTTTGATGCGAAAACAAGATTTCAAATCGCATT
TGCGCCATTTCATTGACAGCGCCCATTCCAACGCTTTGGTGGGTAATTTGTATCGAGCGTTATTCATAGGGGATAGCTTG
AATAAAGATTTAAGAGATAGGGCTAACGCGCTAGGGATCAGCCACTTACTAGCCATTAGCGGGTTTCATTTAGGGATTTT
GAGCGCGAGCGCGTATTTCCTTTTCTCTCTTTTTTATACCCCCTTACAAAAACGCTATTTCCCTTACAGGAACGCTTTTT
ATGATATAGGGGTTTTGGTGTGGGTTTTTTTGCTGGGATATTTATTGCTATTAGATTTTTTACCCTCTTTTTTCAGGGCG
TTTTTAATGGGCTTATTAGGGTTTTTGGCATGCTTTTTTGGGGTAAGGATTTTGAGTTTTAAACTTTTGGTTTTAGCGTG
CTGTATCGCAATAGCGTTACTCCCTAAATTGCTTTTTAGCGTGGGGTTTTTGCTTTCTGTTTGTGGGGTGTGGTATATCT
TTTTGTTTTTAAAACACACTCAAATTTTTTTTAAAGATTCTTCTTTTTTCAAGCGATCGTTTCAAGCGATCGCTTTAAGC
GTGTTAGTGTTTTTGAACATGCTCATTGTCGCGCATGCCTTTTTCCCTATGTTTTCGCCCTACCAGCTTTTTAGCATTCC
TTTAGGCTTGATTTTTATCGTGTTTTTCCCTTTGAGCTTATTCTTGCATGCGGTGGGTTTAGGGTCTTTGTTGGATAGCA
TTCTAAGCATGCCTTTAACCATCCCCACGATTTCGGTTTCTTCGCCTTTATGGCTTTTGGGGGCGCATTTATTTTTAACG
ATTTTAAGCGCGCGTTTTTTTAAGGTTTATTTAAGCATGAATGTTTTAAGCACGGGCTTTTTCTTGTATTGTTGCTATCA
ATATATTATAATGCCTAGTTCAATTGTGGGTTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(159-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A238GWW9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/comE3 Helicobacter pylori 26695

92.906

100

0.929

Multiple sequence alignment