Detailed information NTG1145987

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: BUC38_RS02845
• Genome accession: NZ_LT671674
• Coordinates: 556696..557745 (+)
• Length: 349 a.a.
• NCBI ID: WP_044674235.1
• Uniprot ID: A0A0Z8IIM2
• Organism: Streptococcus suis strain LS9N
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 551696..562745

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUC38_RS02810	-	552211..553305 (+)	1095	WP_044690647.1	sensor histidine kinase	-
BUC38_RS02815	-	553302..553904 (+)	603	WP_044690648.1	response regulator transcription factor	-
BUC38_RS02820	-	554008..554226 (+)	219	WP_024375849.1	YqgQ family protein	-
BUC38_RS02825	-	554226..554612 (+)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
BUC38_RS02830	-	554670..555392 (+)	723	WP_044690649.1	hypothetical protein	-
BUC38_RS02835	rsmD	555692..556231 (+)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
BUC38_RS02840	coaD	556221..556709 (+)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
BUC38_RS02845	sepM	556696..557745 (+)	1050	WP_044674235.1	SepM family pheromone-processing serine protease	Regulator
BUC38_RS02850	-	557933..558574 (+)	642	WP_044690650.1	YutD-like domain-containing protein	-
BUC38_RS02855	rlmN	558583..559695 (+)	1113	WP_044690652.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
BUC38_RS02860	-	559692..560213 (+)	522	WP_044690653.1	VanZ family protein	-
BUC38_RS02865	trpB	560745..561920 (+)	1176	WP_044690724.1	tryptophan synthase subunit beta	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.72 Da
• Isoelectric Point: 4.4261

>NTDB_id=1145987 BUC38_RS02845 WP_044674235.1 556696..557745(+) (sepM) [Streptococcus suis strain LS9N]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTIRSSEEMTGGADNEEYFRIAQFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALADDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLELGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKEDPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=1145987 BUC38_RS02845 WP_044674235.1 556696..557745(+) (sepM) [Streptococcus suis strain LS9N]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTTGCTGCTCAGTTTGATCCC
TATACGACAATTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAAGAGTATTTCCGTATAGCACAGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTACTTGCCTTGGCGGATGATTCGACCTTTAAAAAAGTTCTTAATATTGCTGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAACTTGGAAGTGATGTGACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGAAAAAACGGAATAGGCATCACTCTTGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCAGCAGCTAAGTCAGGTGCAAGTATCTTTTTCG
TACCAAATAATCCAGTTGATGTGGAAGTTTTGAAGGAAGATCCAAAGGCTAAAACCAACTATGAGGAAGCTAAAGAAGCT
GCGGAGAAAGCAGGGTTGGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-311)

• PDZ domain (PDZ_2) (132-195)

3D structure

• AlphaFold DB: A0A0Z8IIM2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	61.095	99.427	0.607