Detailed information
Bioinformatically predicted
Overview
| Name | comB10 | Type | Machinery gene |
| Locus tag | CS886_RS02485 | Genome accession | NZ_LT635478 |
| Coordinates | 498184..499389 (-) | Length | 401 a.a. |
| NCBI ID | WP_089086745.1 | Uniprot ID | A0A238GUL3 |
| Organism | Helicobacter pylori isolate HE142/09 | ||
| Function | transformation-associated type IV transport system (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 447006..528553 | 498184..499389 | within | 0 |
Gene organization within MGE regions
Location: 447006..528553
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CS886_RS02265 | - | 447862..450141 (-) | 2280 | WP_231899392.1 | DEAD/DEAH box helicase family protein | - |
| CS886_RS08395 | - | 450315..451006 (-) | 692 | Protein_432 | type I restriction endonuclease | - |
| CS886_RS02270 | - | 451054..452949 (-) | 1896 | WP_089086720.1 | motility associated factor glycosyltransferase family protein | - |
| CS886_RS02275 | - | 452974..453741 (-) | 768 | WP_089086721.1 | TerB family tellurite resistance protein | - |
| CS886_RS02280 | - | 453751..454065 (-) | 315 | WP_001878784.1 | hypothetical protein | - |
| CS886_RS02285 | - | 454067..455554 (-) | 1488 | WP_089086722.1 | DUF5644 domain-containing protein | - |
| CS886_RS02290 | - | 455566..456054 (-) | 489 | WP_089086723.1 | hypothetical protein | - |
| CS886_RS02295 | - | 456039..457775 (-) | 1737 | WP_089086724.1 | M3 family oligoendopeptidase | - |
| CS886_RS02300 | - | 457872..459122 (-) | 1251 | WP_000431942.1 | cation:proton antiporter | - |
| CS886_RS08400 | - | 459276..459458 (-) | 183 | Protein_440 | hypothetical protein | - |
| CS886_RS02310 | - | 459442..460002 (-) | 561 | WP_000595776.1 | outer membrane beta-barrel protein | - |
| CS886_RS02315 | modA | 460228..460968 (+) | 741 | WP_089086725.1 | molybdate ABC transporter substrate-binding protein | - |
| CS886_RS02320 | modB | 460991..461665 (+) | 675 | WP_000349430.1 | molybdate ABC transporter permease subunit | - |
| CS886_RS02325 | - | 461662..462459 (+) | 798 | WP_089086726.1 | ATP-binding cassette domain-containing protein | - |
| CS886_RS02330 | gltX | 462577..463968 (-) | 1392 | WP_089086727.1 | glutamate--tRNA ligase | - |
| CS886_RS02335 | hopJ | 464086..465198 (+) | 1113 | WP_089086728.1 | Hop family outer membrane protein HopJ/HopK | - |
| CS886_RS02340 | - | 465207..466844 (+) | 1638 | Protein_447 | TaqI-like C-terminal specificity domain-containing protein | - |
| CS886_RS02345 | - | 466810..467658 (+) | 849 | WP_089086729.1 | glycosyltransferase family 9 protein | - |
| CS886_RS02350 | typA | 467704..469503 (+) | 1800 | WP_000790195.1 | translational GTPase TypA | - |
| CS886_RS02355 | - | 469519..469916 (+) | 398 | Protein_450 | DNA adenine methylase | - |
| CS886_RS02360 | - | 470674..472707 (+) | 2034 | WP_089086730.1 | relaxase/mobilization nuclease domain-containing protein | - |
| CS886_RS02365 | - | 473860..474927 (+) | 1068 | Protein_452 | tyrosine-type recombinase/integrase | - |
| CS886_RS02370 | - | 475244..476047 (-) | 804 | WP_089086732.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| CS886_RS02375 | - | 476019..476270 (-) | 252 | WP_000006537.1 | hypothetical protein | - |
| CS886_RS02380 | - | 476402..477082 (-) | 681 | WP_001153463.1 | hypothetical protein | - |
| CS886_RS02385 | - | 477303..478316 (+) | 1014 | WP_089086733.1 | hypothetical protein | - |
| CS886_RS02390 | - | 478321..479597 (-) | 1277 | Protein_457 | hypothetical protein | - |
| CS886_RS02395 | - | 479594..480856 (-) | 1263 | WP_089086734.1 | type IV secretion system protein | - |
| CS886_RS02400 | - | 480853..482286 (-) | 1434 | WP_089086735.1 | hypothetical protein | - |
| CS886_RS02405 | - | 482296..484342 (-) | 2047 | Protein_460 | hypothetical protein | - |
| CS886_RS02410 | - | 484342..485394 (-) | 1053 | WP_089086736.1 | ArdC family protein | - |
| CS886_RS08295 | - | 485395..485559 (-) | 165 | WP_000189763.1 | hypothetical protein | - |
| CS886_RS02420 | - | 486197..486865 (+) | 669 | WP_089086737.1 | ParA family protein | - |
| CS886_RS02425 | - | 486912..487289 (+) | 378 | WP_000365707.1 | hypothetical protein | - |
| CS886_RS02430 | - | 487267..487932 (+) | 666 | WP_089086738.1 | hypothetical protein | - |
| CS886_RS02435 | - | 488006..488809 (-) | 804 | WP_089086739.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| CS886_RS02440 | - | 488779..489249 (-) | 471 | WP_000965788.1 | hypothetical protein | - |
| CS886_RS02445 | - | 489304..491364 (-) | 2061 | WP_001942503.1 | type IA DNA topoisomerase | - |
| CS886_RS02455 | - | 491385..493628 (-) | 2244 | Protein_469 | type IV secretory system conjugative DNA transfer family protein | - |
| CS886_RS02460 | - | 493625..493852 (-) | 228 | Protein_470 | replication regulatory RepB family protein | - |
| CS886_RS02465 | - | 493822..494706 (-) | 885 | WP_089086741.1 | ATPase, T2SS/T4P/T4SS family | - |
| CS886_RS02470 | - | 494711..494986 (-) | 276 | WP_089086742.1 | hypothetical protein | - |
| CS886_RS02475 | - | 495003..495965 (-) | 963 | WP_089086743.1 | hypothetical protein | - |
| CS886_RS02480 | - | 495978..498200 (-) | 2223 | WP_089086744.1 | RGS domain-containing GTPase-activating protein | - |
| CS886_RS02485 | comB10 | 498184..499389 (-) | 1206 | WP_089086745.1 | DNA type IV secretion system protein ComB10 | Machinery gene |
| CS886_RS02490 | - | 499386..501041 (-) | 1656 | WP_000617227.1 | TrbG/VirB9 family P-type conjugative transfer protein | - |
| CS886_RS02495 | - | 501038..502174 (-) | 1137 | WP_089086746.1 | VirB8/TrbF family protein | - |
| CS886_RS08405 | - | 502167..502307 (-) | 141 | WP_000789928.1 | hypothetical protein | - |
| CS886_RS02505 | - | 502304..504854 (-) | 2551 | Protein_479 | VirB4 family type IV secretion/conjugal transfer ATPase | - |
| CS886_RS02510 | - | 504854..505090 (-) | 237 | WP_001168537.1 | hypothetical protein | - |
| CS886_RS02515 | comB3 | 505102..505365 (-) | 264 | WP_001177718.1 | hypothetical protein | Machinery gene |
| CS886_RS02520 | comB2 | 505377..505661 (-) | 285 | WP_000413637.1 | TrbC/VirB2 family protein | Machinery gene |
| CS886_RS02525 | - | 505649..506137 (-) | 489 | WP_089086747.1 | hypothetical protein | - |
| CS886_RS02530 | - | 506201..506359 (-) | 159 | WP_231899360.1 | hypothetical protein | - |
| CS886_RS02535 | - | 506362..507162 (-) | 801 | WP_089086748.1 | integrase | - |
| CS886_RS02540 | - | 507217..507753 (+) | 537 | Protein_486 | DNA adenine methylase | - |
| CS886_RS02545 | - | 507756..508379 (+) | 624 | WP_089086749.1 | GIY-YIG nuclease family protein | - |
| CS886_RS02550 | - | 508527..508889 (+) | 363 | Protein_488 | DNA cytosine methyltransferase | - |
| CS886_RS02555 | - | 509049..509993 (-) | 945 | WP_089086751.1 | catalase family peroxidase | - |
| CS886_RS02560 | hofC | 510280..511866 (+) | 1587 | WP_089086752.1 | outer membrane beta-barrel protein HofC | - |
| CS886_RS02565 | hofD | 511938..513335 (+) | 1398 | WP_089086753.1 | outer membrane beta-barrel protein HofD | - |
| CS886_RS02580 | - | 513653..516112 (+) | 2460 | WP_414842625.1 | DUF3519 domain-containing protein | - |
| CS886_RS02585 | - | 516122..516543 (+) | 422 | Protein_493 | hypothetical protein | - |
| CS886_RS02590 | - | 516540..517087 (+) | 548 | Protein_494 | hypothetical protein | - |
| CS886_RS02595 | - | 517327..518463 (-) | 1137 | WP_000461999.1 | potassium channel family protein | - |
| CS886_RS02605 | rpmB | 518650..518838 (-) | 189 | WP_001118998.1 | 50S ribosomal protein L28 | - |
| CS886_RS02610 | - | 518931..519770 (-) | 840 | WP_089086759.1 | HpaA family protein | - |
| CS886_RS02615 | mraY | 519901..520962 (+) | 1062 | WP_089087378.1 | phospho-N-acetylmuramoyl-pentapeptide- transferase | - |
| CS886_RS02620 | murD | 520964..522232 (+) | 1269 | WP_089086760.1 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase | - |
| CS886_RS02625 | - | 522229..522489 (-) | 261 | WP_089086761.1 | DUF493 family protein | - |
| CS886_RS02630 | - | 522479..522787 (-) | 309 | WP_089086762.1 | hotdog domain-containing protein | - |
| CS886_RS02635 | - | 523020..524348 (+) | 1329 | WP_000526620.1 | sodium-dependent transporter | - |
| CS886_RS02640 | - | 524359..525687 (+) | 1329 | WP_089086763.1 | sodium-dependent transporter | - |
| CS886_RS02645 | - | 525702..526768 (+) | 1067 | Protein_504 | phospholipase A | - |
| CS886_RS02650 | dnaN | 526824..527948 (+) | 1125 | WP_089086764.1 | DNA polymerase III subunit beta | - |
Sequence
Protein
Download Length: 401 a.a. Molecular weight: 44905.59 Da Isoelectric Point: 10.1066
>NTDB_id=1145892 CS886_RS02485 WP_089086745.1 498184..499389(-) (comB10) [Helicobacter pylori isolate HE142/09]
MKQSLLKKIGLGVGGFVVLMALGLLANKGSNNNNKEEIFQVSESKFPLSDYFFEEVKEEPKKAKETPEVTTQEPTTQTSP
NPSVSANPNIKDYSHLNNNLNQQNNTITHLQQVLQSPSKIKPKPKHTKEQLEFLNTRLKPLEPTKPATKPEMEYGVDSFT
NLKYKDIGTNEHKLLRTITADRMIPAFLITPISSQIAGKVTAQVESDIFASMGRAVLIPKGSKVIGYYNNNNQIGQYRLN
IAWTRIITPQGINIMLTNARGADVKGYNGLVGKYISRNFQRYGIPLLTNTLSNGLLIGITSALANRQNRKGDGNPFFGDY
LLMQLTRNTGMGINQVINQMLRQYGAQNPIIIIREGSRVFISPNLDIFIPKPKDGEVLAEFFKEKKPLIKTKEEINNEEE
I
MKQSLLKKIGLGVGGFVVLMALGLLANKGSNNNNKEEIFQVSESKFPLSDYFFEEVKEEPKKAKETPEVTTQEPTTQTSP
NPSVSANPNIKDYSHLNNNLNQQNNTITHLQQVLQSPSKIKPKPKHTKEQLEFLNTRLKPLEPTKPATKPEMEYGVDSFT
NLKYKDIGTNEHKLLRTITADRMIPAFLITPISSQIAGKVTAQVESDIFASMGRAVLIPKGSKVIGYYNNNNQIGQYRLN
IAWTRIITPQGINIMLTNARGADVKGYNGLVGKYISRNFQRYGIPLLTNTLSNGLLIGITSALANRQNRKGDGNPFFGDY
LLMQLTRNTGMGINQVINQMLRQYGAQNPIIIIREGSRVFISPNLDIFIPKPKDGEVLAEFFKEKKPLIKTKEEINNEEE
I
Nucleotide
Download Length: 1206 bp
>NTDB_id=1145892 CS886_RS02485 WP_089086745.1 498184..499389(-) (comB10) [Helicobacter pylori isolate HE142/09]
ATGAAACAATCCTTGCTTAAAAAGATAGGCTTAGGTGTTGGGGGCTTTGTTGTTTTAATGGCATTAGGATTGCTTGCTAA
TAAAGGCTCAAACAATAACAATAAAGAAGAAATCTTTCAAGTAAGTGAGAGTAAATTCCCTTTAAGTGATTATTTCTTTG
AAGAAGTCAAAGAAGAGCCAAAAAAAGCCAAAGAAACACCAGAAGTAACTACCCAAGAGCCTACAACACAAACTAGCCCC
AATCCTAGTGTTTCAGCTAATCCTAACATTAAAGATTATAGTCATCTTAACAACAATCTTAATCAGCAAAATAATACTAT
CACGCATTTACAACAAGTTTTACAAAGCCCCTCTAAAATAAAGCCTAAACCAAAGCATACTAAAGAGCAATTAGAATTTT
TAAACACACGCCTTAAACCTTTAGAACCAACTAAACCAGCCACTAAGCCTGAGATGGAATACGGCGTGGATAGTTTTACT
AATTTAAAATATAAAGACATCGGCACTAATGAGCATAAGCTTTTAAGAACCATAACCGCTGATAGAATGATACCAGCCTT
TTTAATCACGCCTATTAGCTCTCAAATTGCTGGAAAAGTAACCGCCCAAGTAGAGAGCGATATATTTGCTTCTATGGGTA
GAGCGGTGCTAATCCCTAAAGGCTCTAAAGTTATAGGCTATTACAATAATAACAATCAAATTGGACAATACCGCCTTAAC
ATTGCTTGGACTAGAATTATCACGCCTCAAGGCATAAACATCATGCTCACTAACGCAAGGGGGGCTGATGTGAAGGGTTA
TAATGGCTTAGTAGGCAAATACATTAGCCGAAACTTTCAACGCTATGGTATCCCCTTACTCACTAACACGCTCTCTAATG
GTCTTTTAATAGGAATTACTTCAGCCTTAGCTAATAGGCAAAATAGAAAGGGTGATGGCAACCCTTTTTTTGGGGATTAC
TTGCTTATGCAACTCACTAGAAATACAGGCATGGGCATCAATCAAGTTATCAATCAAATGCTAAGGCAATATGGAGCGCA
AAACCCCATTATCATCATTAGAGAGGGGAGCAGAGTGTTTATTAGCCCTAATTTAGACATCTTTATCCCTAAACCAAAAG
ATGGGGAGGTTTTAGCGGAGTTCTTTAAAGAGAAAAAACCCCTAATCAAAACAAAAGAGGAAATTAACAATGAAGAAGAA
ATCTAA
ATGAAACAATCCTTGCTTAAAAAGATAGGCTTAGGTGTTGGGGGCTTTGTTGTTTTAATGGCATTAGGATTGCTTGCTAA
TAAAGGCTCAAACAATAACAATAAAGAAGAAATCTTTCAAGTAAGTGAGAGTAAATTCCCTTTAAGTGATTATTTCTTTG
AAGAAGTCAAAGAAGAGCCAAAAAAAGCCAAAGAAACACCAGAAGTAACTACCCAAGAGCCTACAACACAAACTAGCCCC
AATCCTAGTGTTTCAGCTAATCCTAACATTAAAGATTATAGTCATCTTAACAACAATCTTAATCAGCAAAATAATACTAT
CACGCATTTACAACAAGTTTTACAAAGCCCCTCTAAAATAAAGCCTAAACCAAAGCATACTAAAGAGCAATTAGAATTTT
TAAACACACGCCTTAAACCTTTAGAACCAACTAAACCAGCCACTAAGCCTGAGATGGAATACGGCGTGGATAGTTTTACT
AATTTAAAATATAAAGACATCGGCACTAATGAGCATAAGCTTTTAAGAACCATAACCGCTGATAGAATGATACCAGCCTT
TTTAATCACGCCTATTAGCTCTCAAATTGCTGGAAAAGTAACCGCCCAAGTAGAGAGCGATATATTTGCTTCTATGGGTA
GAGCGGTGCTAATCCCTAAAGGCTCTAAAGTTATAGGCTATTACAATAATAACAATCAAATTGGACAATACCGCCTTAAC
ATTGCTTGGACTAGAATTATCACGCCTCAAGGCATAAACATCATGCTCACTAACGCAAGGGGGGCTGATGTGAAGGGTTA
TAATGGCTTAGTAGGCAAATACATTAGCCGAAACTTTCAACGCTATGGTATCCCCTTACTCACTAACACGCTCTCTAATG
GTCTTTTAATAGGAATTACTTCAGCCTTAGCTAATAGGCAAAATAGAAAGGGTGATGGCAACCCTTTTTTTGGGGATTAC
TTGCTTATGCAACTCACTAGAAATACAGGCATGGGCATCAATCAAGTTATCAATCAAATGCTAAGGCAATATGGAGCGCA
AAACCCCATTATCATCATTAGAGAGGGGAGCAGAGTGTTTATTAGCCCTAATTTAGACATCTTTATCCCTAAACCAAAAG
ATGGGGAGGTTTTAGCGGAGTTCTTTAAAGAGAAAAAACCCCTAATCAAAACAAAAGAGGAAATTAACAATGAAGAAGAA
ATCTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB10 | Helicobacter pylori P1 |
52.821 |
97.257 |
0.514 |