Detailed information NTG1145809

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: CS896_RS00235
• Genome accession: NZ_LT635474
• Coordinates: 42074..43210 (+)
• Length: 378 a.a.
• NCBI ID: WP_089086477.1
• Uniprot ID: A0A238GTD4
• Organism: Helicobacter pylori isolate HE171/09
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 37074..48210

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CS896_RS00200	panD	37501..37854 (+)	354	WP_000142286.1	aspartate 1-decarboxylase	-
CS896_RS00205	-	37857..38159 (+)	303	WP_000347926.1	YbaB/EbfC family nucleoid-associated protein	-
CS896_RS00210	-	38159..39163 (+)	1005	WP_089086474.1	PDZ domain-containing protein	-
CS896_RS00215	comB6	39171..40226 (+)	1056	WP_089086475.1	P-type conjugative transfer protein TrbL	Machinery gene
CS896_RS00220	comB7	40242..40355 (+)	114	WP_001217877.1	hypothetical protein	Machinery gene
CS896_RS00225	comB8	40352..41095 (+)	744	WP_000660557.1	type IV secretion system protein	Machinery gene
CS896_RS00230	comB9	41095..42081 (+)	987	WP_089086476.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
CS896_RS00235	comB10	42074..43210 (+)	1137	WP_089086477.1	DNA type IV secretion system protein ComB10	Machinery gene
CS896_RS00240	-	43280..44692 (+)	1413	WP_089086478.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
CS896_RS00245	gmd	44733..45878 (+)	1146	WP_089086479.1	GDP-mannose 4,6-dehydratase	-
CS896_RS00250	-	45871..46803 (+)	933	WP_001002481.1	GDP-L-fucose synthase family protein	-
CS896_RS08265	-	46831..47040 (-)	210	Protein_44	anthranilate synthase component I	-
CS896_RS08370	-	47191..47484 (-)	294	WP_099167445.1	hypothetical protein	-

Sequence

Protein

• Length: 378 a.a.
• Molecular weight: 42184.68 Da
• Isoelectric Point: 9.7473

>NTDB_id=1145809 CS896_RS00235 WP_089086477.1 42074..43210(+) (comB10) [Helicobacter pylori isolate HE171/09]
MNKWLKGAIVFIGGFATITTISLIYHQKPKAPLNNQPSLLNDDEVKYPLQDYTFTQNPQPTNTESSKDATIKALQEQLKA
ALKALNSKEMNYSKEETFTSPPMDPKINTTPPKKDFSLKQLDLLASRITPFKQSPKNYEENLIFPVDNPNGIDGFTNLKE
KDTATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFASMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWS
RIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEEVTNFFGDYLLLQL
MRQSGMGINQVVNQILRDKSKIAPIVVIREGSRVFISPNTDIFFPIPRENEVIAEFLK

Nucleotide

• Length: 1137 bp

>NTDB_id=1145809 CS896_RS00235 WP_089086477.1 42074..43210(+) (comB10) [Helicobacter pylori isolate HE171/09]
GTGAATAAGTGGCTTAAAGGGGCGATTGTTTTTATAGGGGGTTTTGCAACGATTACAACCATTTCTTTAATCTACCACCA
AAAGCCAAAAGCCCCCTTAAATAACCAACCTAGCCTTTTGAATGATGATGAGGTGAAATACCCCTTACAAGACTACACCT
TCACTCAAAACCCACAGCCAACTAACACGGAAAGCTCTAAAGACGCCACCATTAAAGCCTTACAAGAACAACTCAAAGCC
GCTTTAAAAGCCTTAAATTCCAAAGAAATGAACTATTCCAAAGAAGAAACTTTTACTAGCCCTCCCATGGATCCAAAAAT
AAACACAACCCCCCCTAAAAAAGACTTTTCTTTAAAGCAATTAGATTTACTAGCCTCTCGCATCACCCCTTTCAAACAAA
GCCCTAAAAATTACGAAGAAAACCTGATTTTCCCTGTGGATAACCCTAATGGCATTGATGGTTTCACTAACCTTAAAGAA
AAAGACACCGCCACTAATGAAAACAAGCTTTTACGCACCATTACAGCTGACAAAATGATACCCGCCTTTTTGATCACGCC
CATTTCTAGCCAGATCGCTGGTAAAGTGATTGCGCAAGTGGAAAGCGATATTTTTGCGAGCATGGGCAAAGCCGTCTTAA
TCCCTAAAGGCTCTAAAGTCATAGGCTATTACAGCAACAATAACAAAATGGGCGAATACCGCTTGGATATTGTATGGAGT
CGAATCATCACTCCCCATGGCATTAATATCATGCTCACTAACGCTAAAGGGGCGGACATTAAAGGCTATAACGGATTAGT
GGGGGAATTGATTGAAAGGAATTTCCAACGCTATGGCGTGCCGTTACTGCTTTCTACGCTCACTAACGGCTTATTGATTG
GGATCACTTCGGCTTTAAACAATAGAGGCAATAAAGAAGAGGTGACTAATTTCTTTGGGGATTATCTTTTATTGCAATTG
ATGAGGCAAAGCGGCATGGGGATCAATCAAGTCGTCAATCAAATTTTAAGAGACAAGAGCAAGATCGCCCCCATTGTGGT
GATTAGAGAGGGAAGCAGGGTTTTCATTTCGCCCAATACTGATATATTCTTCCCTATACCCAGAGAGAATGAAGTCATCG
CAGAGTTTTTGAAGTGA

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (173-364)

3D structure

• AlphaFold DB: A0A238GTD4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	96.561	100	0.966