Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/comE3   Type   Machinery gene
Locus tag   CS888_RS06565 Genome accession   NZ_LT635473
Coordinates   1325323..1326636 (-) Length   437 a.a.
NCBI ID   WP_172825131.1    Uniprot ID   A0A238GWW9
Organism   Helicobacter pylori isolate HE136/09     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1320323..1331636
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CS888_RS06535 nadC 1320786..1321607 (-) 822 WP_001918844.1 carboxylating nicotinate-nucleotide diphosphorylase -
  CS888_RS06540 nadA 1321607..1322617 (-) 1011 WP_001141844.1 quinolinate synthase NadA -
  CS888_RS06545 - 1322607..1323410 (-) 804 WP_089087185.1 phosphatidylserine decarboxylase -
  CS888_RS06550 - 1323404..1323910 (-) 507 WP_000953090.1 DUF6115 domain-containing protein -
  CS888_RS06555 - 1323923..1324417 (-) 495 WP_172825130.1 hypothetical protein -
  CS888_RS06560 mqnP 1324410..1325252 (-) 843 WP_231899378.1 menaquinone biosynthesis prenyltransferase MqnP -
  CS888_RS06565 comEC/comE3 1325323..1326636 (-) 1314 WP_172825131.1 ComEC/Rec2 family competence protein Machinery gene
  CS888_RS06570 - 1326633..1328093 (-) 1461 WP_089087188.1 replicative DNA helicase -
  CS888_RS06575 - 1328104..1329498 (-) 1395 WP_089087189.1 NAD(P)H-hydrate dehydratase -
  CS888_RS06580 crdS 1329501..1330703 (-) 1203 WP_089087190.1 copper-sensing histidine kinase CrdS -
  CS888_RS06585 crdR 1330669..1331310 (-) 642 WP_089087191.1 copper response regulator transcription factor CrdR -
  CS888_RS06590 - 1331446..1331547 (-) 102 Protein_1254 anthranilate synthase component I -

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 50064.86 Da        Isoelectric Point: 9.8459

>NTDB_id=1145797 CS888_RS06565 WP_172825131.1 1325323..1326636(-) (comEC/comE3) [Helicobacter pylori isolate HE136/09]
MKDKTFQGAFELLATPKEYSWCGVVLSLLLVINLYLEYLNYQKLDFSKPTSLNAQILLQYPKTKDQKTYFVLKLQSKGMI
FYTTIKEPLKNLQYRHAHFFGKIKSCSFLESLKSCFFQTYSFSLMRKQDFKSHLRHFIDSAHSNALVGNLYRALFIGDSL
NKDLRDRANALGISHLLAISGFHLGILSASAYFLFSLFYTPLQKRYFPYRNAFYDIGVLVWVFLLGYLLLLDFLPSFFRA
FLMGLLGFLACFFGVRILSFKLLVLACCIAIALLPKLLFSVGFLLSVCGVWYIFLFLKHTQIFFKDSSFFKRSFQAIALS
VLVFLNMLIVAHAFFPMFSPYQLFSIPLGLIFIVFFPLSLFLHAVGLGSLLDSILSMPLTIPTISVSSPLWLLGAHLFLT
ILSARFFKVYLSMNVLSTGFFLYCCYQYIIMPSSIVG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=1145797 CS888_RS06565 WP_172825131.1 1325323..1326636(-) (comEC/comE3) [Helicobacter pylori isolate HE136/09]
TTGAAAGATAAAACTTTTCAGGGGGCGTTTGAACTTCTTGCAACCCCCAAAGAATACTCATGGTGTGGGGTTGTTTTAAG
CCTTTTGTTGGTGATCAACCTTTATTTAGAATACTTGAATTACCAAAAGCTTGATTTTTCAAAACCTACAAGCCTGAACG
CTCAAATCTTATTACAATACCCTAAAACTAAAGATCAAAAAACCTATTTTGTCTTAAAGCTCCAATCTAAGGGCATGATC
TTTTACACCACCATTAAAGAGCCTTTAAAAAACCTCCAATACCGCCACGCGCATTTTTTTGGCAAGATCAAATCTTGCTC
GTTCTTAGAGTCTCTAAAATCATGCTTTTTTCAAACTTATTCTTTTTCTTTGATGCGAAAACAAGATTTCAAATCGCATT
TGCGCCATTTCATTGACAGCGCCCATTCCAACGCTTTGGTGGGTAATTTGTATCGAGCGTTATTCATAGGGGATAGCTTG
AATAAAGATTTAAGAGATAGGGCTAACGCGCTAGGGATCAGCCACTTACTAGCCATTAGCGGGTTTCATTTAGGGATTTT
GAGCGCGAGCGCGTATTTCCTTTTCTCTCTTTTTTATACCCCCTTACAAAAACGCTATTTCCCTTACAGGAACGCTTTTT
ATGATATAGGGGTTTTGGTGTGGGTTTTTTTGCTGGGATATTTATTGCTATTAGATTTTTTACCCTCTTTTTTCAGGGCG
TTTTTAATGGGCTTATTAGGGTTTTTGGCATGCTTTTTTGGGGTAAGGATTTTGAGTTTTAAACTTTTGGTTTTAGCGTG
CTGTATCGCAATAGCGTTACTCCCTAAATTGCTTTTTAGCGTGGGGTTTTTGCTTTCTGTTTGTGGGGTGTGGTATATCT
TTTTGTTTTTAAAACACACTCAAATTTTTTTTAAAGATTCTTCTTTTTTCAAGCGATCGTTTCAAGCGATCGCTTTAAGC
GTGTTAGTGTTTTTGAACATGCTCATTGTCGCGCATGCCTTTTTCCCTATGTTTTCGCCCTACCAGCTTTTTAGCATTCC
TTTAGGCTTGATTTTTATCGTGTTTTTCCCTTTGAGCTTATTCTTGCATGCGGTGGGTTTAGGGTCTTTGTTGGATAGCA
TTCTAAGCATGCCTTTAACCATCCCCACGATTTCGGTTTCTTCGCCTTTATGGCTTTTGGGGGCGCATTTATTTTTAACG
ATTTTAAGCGCGCGTTTTTTTAAGGTTTATTTAAGCATGAATGTTTTAAGCACGGGCTTTTTCTTGTATTGTTGCTATCA
ATATATTATAATGCCTAGTTCAATTGTGGGTTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(159-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A238GWW9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/comE3 Helicobacter pylori 26695

92.906

100

0.929

Multiple sequence alignment