Detailed information NTG1145665

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: CS894_RS00240
• Genome accession: NZ_LT635456
• Coordinates: 42071..43207 (+)
• Length: 378 a.a.
• NCBI ID: WP_089086477.1
• Uniprot ID: A0A238GTD4
• Organism: Helicobacter pylori isolate HE101/09
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 37071..48207

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CS894_RS00205	panD	37498..37851 (+)	354	WP_000142286.1	aspartate 1-decarboxylase	-
CS894_RS00210	-	37854..38156 (+)	303	WP_000347926.1	YbaB/EbfC family nucleoid-associated protein	-
CS894_RS00215	-	38156..39160 (+)	1005	WP_089086474.1	PDZ domain-containing protein	-
CS894_RS00220	comB6	39168..40223 (+)	1056	WP_089086475.1	P-type conjugative transfer protein TrbL	Machinery gene
CS894_RS00225	comB7	40239..40352 (+)	114	WP_001217877.1	hypothetical protein	Machinery gene
CS894_RS00230	comB8	40349..41092 (+)	744	WP_000660557.1	type IV secretion system protein	Machinery gene
CS894_RS00235	comB9	41092..42078 (+)	987	WP_089086476.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
CS894_RS00240	comB10	42071..43207 (+)	1137	WP_089086477.1	DNA type IV secretion system protein ComB10	Machinery gene
CS894_RS00245	-	43277..44689 (+)	1413	WP_089086478.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
CS894_RS00250	gmd	44730..45875 (+)	1146	WP_089086479.1	GDP-mannose 4,6-dehydratase	-
CS894_RS00255	-	45868..46800 (+)	933	WP_001002481.1	GDP-L-fucose synthase family protein	-
CS894_RS08265	-	46828..47037 (-)	210	Protein_44	anthranilate synthase component I	-
CS894_RS08365	-	47188..47481 (-)	294	WP_099167445.1	hypothetical protein	-

Sequence

Protein

• Length: 378 a.a.
• Molecular weight: 42184.68 Da
• Isoelectric Point: 9.7473

>NTDB_id=1145665 CS894_RS00240 WP_089086477.1 42071..43207(+) (comB10) [Helicobacter pylori isolate HE101/09]
MNKWLKGAIVFIGGFATITTISLIYHQKPKAPLNNQPSLLNDDEVKYPLQDYTFTQNPQPTNTESSKDATIKALQEQLKA
ALKALNSKEMNYSKEETFTSPPMDPKINTTPPKKDFSLKQLDLLASRITPFKQSPKNYEENLIFPVDNPNGIDGFTNLKE
KDTATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFASMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWS
RIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEEVTNFFGDYLLLQL
MRQSGMGINQVVNQILRDKSKIAPIVVIREGSRVFISPNTDIFFPIPRENEVIAEFLK

Nucleotide

• Length: 1137 bp

>NTDB_id=1145665 CS894_RS00240 WP_089086477.1 42071..43207(+) (comB10) [Helicobacter pylori isolate HE101/09]
GTGAATAAGTGGCTTAAAGGGGCGATTGTTTTTATAGGGGGTTTTGCAACGATTACAACCATTTCTTTAATCTACCACCA
AAAGCCAAAAGCCCCCTTAAATAACCAACCTAGCCTTTTGAATGATGATGAGGTGAAATACCCCTTACAAGACTACACCT
TCACTCAAAACCCACAGCCAACTAACACGGAAAGCTCTAAAGACGCCACCATTAAAGCCTTACAAGAACAACTCAAAGCC
GCTTTAAAAGCCTTAAATTCCAAAGAAATGAACTATTCCAAAGAAGAAACTTTTACTAGCCCTCCCATGGATCCAAAAAT
AAACACAACCCCCCCTAAAAAAGACTTTTCTTTAAAGCAATTAGATTTACTAGCCTCTCGCATCACCCCTTTCAAACAAA
GCCCTAAAAATTACGAAGAAAACCTGATTTTCCCTGTGGATAACCCTAATGGCATTGATGGTTTCACTAACCTTAAAGAA
AAAGACACCGCCACTAATGAAAACAAGCTTTTACGCACCATTACAGCTGACAAAATGATACCCGCCTTTTTGATCACGCC
CATTTCTAGCCAGATCGCTGGTAAAGTGATTGCGCAAGTGGAAAGCGATATTTTTGCGAGCATGGGCAAAGCCGTCTTAA
TCCCTAAAGGCTCTAAAGTCATAGGCTATTACAGCAACAATAACAAAATGGGCGAATACCGCTTGGATATTGTATGGAGT
CGAATCATCACTCCCCATGGCATTAATATCATGCTCACTAACGCTAAAGGGGCGGACATTAAAGGCTATAACGGATTAGT
GGGGGAATTGATTGAAAGGAATTTCCAACGCTATGGCGTGCCGTTACTGCTTTCTACGCTCACTAACGGCTTATTGATTG
GGATCACTTCGGCTTTAAACAATAGAGGCAATAAAGAAGAGGTGACTAATTTCTTTGGGGATTATCTTTTATTGCAATTG
ATGAGGCAAAGCGGCATGGGGATCAATCAAGTCGTCAATCAAATTTTAAGAGACAAGAGCAAGATCGCCCCCATTGTGGT
GATTAGAGAGGGAAGCAGGGTTTTCATTTCGCCCAATACTGATATATTCTTCCCTATACCCAGAGAGAATGAAGTCATCG
CAGAGTTTTTGAAGTGA

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (173-364)

3D structure

• AlphaFold DB: A0A238GTD4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	96.561	100	0.966