Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   BQ3358_RS10430 Genome accession   NZ_LT615218
Coordinates   2048603..2049319 (+) Length   238 a.a.
NCBI ID   WP_064127170.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AUS0325     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2043603..2054319
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BQ3358_RS10400 - 2044000..2044445 (+) 446 Protein_1985 nitroreductase family protein -
  BQ3358_RS10405 - 2044806..2045591 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  BQ3358_RS15195 hld 2046191..2046271 (-) 81 WP_000046022.1 delta-hemolysin -
  BQ3358_RS10415 - 2046560..2047123 (+) 564 WP_001105704.1 accessory gene regulator AgrB -
  BQ3358_RS10420 agrD 2047127..2047267 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  BQ3358_RS10425 agrC 2047292..2048584 (+) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  BQ3358_RS10430 agrA 2048603..2049319 (+) 717 WP_064127170.1 quorum-sensing response regulator AgrA Regulator
  BQ3358_RS10435 - 2049391..2049500 (+) 110 Protein_1992 hypothetical protein -
  BQ3358_RS10440 - 2049688..2050647 (-) 960 WP_001253293.1 carbohydrate kinase family protein -
  BQ3358_RS10445 - 2050644..2052128 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  BQ3358_RS10450 - 2052277..2053227 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27961.97 Da        Isoelectric Point: 6.0927

>NTDB_id=1145313 BQ3358_RS10430 WP_064127170.1 2048603..2049319(+) (agrA) [Staphylococcus aureus strain AUS0325]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPVELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1145313 BQ3358_RS10430 WP_064127170.1 2048603..2049319(+) (agrA) [Staphylococcus aureus strain AUS0325]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGTAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992

Multiple sequence alignment