Detailed information NTG1145311

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BQ3358_RS09695
• Genome accession: NZ_LT615218
• Coordinates: 1928449..1929492 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AUS0325
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1923449..1934492

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BQ3358_RS09665	-	1923871..1925127 (-)	1257	WP_072398252.1	aminopeptidase	-
BQ3358_RS09670	-	1925130..1925330 (-)	201	WP_000180460.1	DUF1128 family protein	-
BQ3358_RS09675	-	1925477..1925941 (+)	465	WP_000567539.1	low molecular weight protein-tyrosine-phosphatase	-
BQ3358_RS09680	-	1925948..1926223 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
BQ3358_RS09685	-	1926501..1927718 (+)	1218	WP_069992009.1	YihY/virulence factor BrkB family protein	-
BQ3358_RS09690	vraR	1927830..1928459 (-)	630	WP_000153532.1	two-component system response regulator VraR	Regulator
BQ3358_RS09695	vraS	1928449..1929492 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
BQ3358_RS09700	liaF	1929489..1930190 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
BQ3358_RS09705	-	1930205..1930591 (-)	387	WP_001110179.1	hypothetical protein	-
BQ3358_RS09710	map	1930808..1931566 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
BQ3358_RS09715	-	1932038..1933024 (+)	987	WP_000999713.1	FUSC family protein	-
BQ3358_RS09725	-	1933455..1933868 (-)	414	WP_025175030.1	hypothetical protein	-
BQ3358_RS09730	-	1933897..1934007 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1145311 BQ3358_RS09695 WP_001017131.1 1928449..1929492(-) (vraS) [Staphylococcus aureus strain AUS0325]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1145311 BQ3358_RS09695 WP_001017131.1 1928449..1929492(-) (vraS) [Staphylococcus aureus strain AUS0325]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTGAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1