Detailed information NTG1144844

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: BN8422_RS14510
• Genome accession: NZ_LT598688
• Coordinates: 2775181..2776068 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus isolate Sa_Newman_UoM
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2770181..2781068

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BN8422_RS14475	-	2770200..2770292 (+)	93	WP_010956583.1	hypothetical protein	-
BN8422_RS14480	-	2770400..2770897 (-)	498	WP_001065268.1	glutathione peroxidase	-
BN8422_RS14485	-	2770907..2771167 (-)	261	WP_001789910.1	hypothetical protein	-
BN8422_RS14490	-	2771549..2771662 (-)	114	WP_011447078.1	hypothetical protein	-
BN8422_RS14500	-	2772321..2774321 (-)	2001	WP_000776751.1	ABC transporter permease	-
BN8422_RS14505	-	2774318..2775073 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
BN8422_RS14510	braS	2775181..2776068 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
BN8422_RS14515	braR	2776079..2776744 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
BN8422_RS14520	-	2776770..2776970 (-)	201	WP_000604728.1	hypothetical protein	-
BN8422_RS14530	-	2777168..2778592 (+)	1425	WP_000953744.1	alkaline phosphatase	-
BN8422_RS16030	-	2778652..2778753 (-)	102	WP_000731972.1	SE2200 family small protein	-
BN8422_RS14540	-	2778875..2779330 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
BN8422_RS14545	-	2779575..2780336 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1144844 BN8422_RS14510 WP_000143419.1 2775181..2776068(-) (braS) [Staphylococcus aureus isolate Sa_Newman_UoM]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1144844 BN8422_RS14510 WP_000143419.1 2775181..2776068(-) (braS) [Staphylococcus aureus isolate Sa_Newman_UoM]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997