Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C7S03_RS11385 Genome accession   NZ_LT592163
Coordinates   1932337..1935450 (+) Length   1037 a.a.
NCBI ID   WP_144998613.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_W     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1927337..1940450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7S03_RS11360 (WHOW_02128C) - 1927879..1928328 (-) 450 WP_003692085.1 CopD family copper resistance protein -
  C7S03_RS11365 (WHOW_02129C) waaA 1928369..1929640 (-) 1272 WP_010360974.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  C7S03_RS11370 (WHOW_02130C) gnd 1929703..1931151 (-) 1449 WP_003688061.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  C7S03_RS11375 (WHOW_02131C) - 1931231..1931494 (-) 264 WP_017147189.1 hypothetical protein -
  C7S03_RS11385 (WHOW_02132) pilC 1932337..1935450 (+) 3114 WP_144998613.1 PilC family type IV pilus tip adhesin Machinery gene
  C7S03_RS11400 (WHOW_02134) - 1936102..1936386 (+) 285 WP_003692093.1 GIY-YIG nuclease family protein -
  C7S03_RS11410 (WHOW_02135C) yccS 1936865..1939015 (-) 2151 WP_003699137.1 YccS family putative transporter -
  C7S03_RS11415 (WHOW_02136C) - 1939132..1940358 (-) 1227 WP_003697786.1 PilT/PilU family type 4a pilus ATPase -

Sequence

Protein


Download         Length: 1037 a.a.        Molecular weight: 113407.21 Da        Isoelectric Point: 10.0132

>NTDB_id=1144609 C7S03_RS11385 WP_144998613.1 1932337..1935450(+) (pilC) [Neisseria gonorrhoeae strain WHO_W]
MNKTLKRRVFRHTALYTAILMFSHTGGGGGAMAQTHKYAIIMNERKQPEVKWETQYSQSALKDKGRERTFSHTSQKGRFN
ITHNFISFNNNDTLVSQQSGTAVFGTATYLPPYGKVSGFDTDRLKKRNNAVDWIRTTRIALAGYSYEGVVCRSGTGCPKL
VYKTRFSFDNPDLVKNAGKLDRYTDLSRENSPIYKLKDYPWLGVSFNLSSENTVKDSKLSNKLISSFSESNNNQTIVSTT
EDHPISLGGSQREHTAVAYYLNAKLHLLDKKGIGDIAPGKTVRLGLLKPSIDVRKGNTGLSGILSFNATWDIKDTGQIPV
KLGLPEVKAGRCINKPNPNPKSALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSKIFLQNLSRNDDKNKPGRYSL
KPLSENEIKSKEPRFNGRQTVIRLDSGVQLIKLNGSKDEVVIFGNNGNNGTFGIVKEANVNLEADEWKKVLLPWTVRGPD
NDNKFKLINQKPDRYSQRYRIRENGNRDLGDIVNSPIVAVGGYLATSANDGMVHIFKKTGTDERSYNLKLSYIPGTMERK
DIEGNDSDLAKELRTFAEKGYVGDRYGVDGGFVLRQVNLNGQDRVFMFGAMGLGGRGAYALDLSKINEKYPAAAPLFDVK
NGDKNGKNGKNRVEVELGYTVGTPQIGKIRNGKYAAFLASGYAAKQIASQENKTALYVYDLKDTLGTPIAKIEVKGGKGG
LSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSNSDPSKWSVSTIFEGGKPITSAPAVSRLADKRVVIFGTGSDLTEDDV
LDTKEQYIYGIFDDDKAANNVNASRGVLGSGLLEQHLTQENKTLFLNKRSDGSGSKGWAVKLTGGRRVTVKPTVVLRTAF
VTIRKYKDDGCGAETAILGINTADGGALTPRSARPIVPEANTAVAQYSGHKKTAGGKSVPIGCMWKNSKTVCPNGYVYDK
PVNVRYLDETETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3114 bp        

>NTDB_id=1144609 C7S03_RS11385 WP_144998613.1 1932337..1935450(+) (pilC) [Neisseria gonorrhoeae strain WHO_W]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGAGA
CTCAATATAGTCAATCAGCATTAAAGGACAAAGGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAGGCAGGTTCAAC
ATCACACACAATTTTATCTCATTCAACAATAACGATACCCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGC
CACCTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGGCTGAAAAAGCGCAACAATGCCGTTGATTGGA
TTCGTACCACCCGCATCGCGCTGGCAGGCTACAGCTACGAAGGTGTCGTATGCAGAAGCGGCACAGGCTGTCCCAAACTT
GTCTATAAAACCCGATTTTCCTTCGATAATCCCGACTTGGTAAAAAATGCGGGCAAGCTGGATAGGTACACAGACCTAAG
CCGCGAAAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGAGCAGCGAGAATACCG
TCAAAGATAGCAAATTATCCAACAAATTGATATCTTCTTTTAGTGAAAGCAATAATAATCAAACCATCGTCTCTACGACA
GAAGATCACCCTATTTCCCTTGGCGGCTCGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCT
GCTGGATAAAAAAGGGATTGGAGATATCGCGCCAGGCAAAACAGTGCGGTTGGGTCTCTTGAAGCCGAGCATCGATGTGC
GGAAAGGAAATACGGGGCTTAGCGGCATTCTATCTTTTAATGCTACGTGGGACATTAAAGATACCGGGCAGATTCCGGTC
AAGCTCGGCCTGCCGGAAGTCAAAGCAGGCCGCTGCATCAACAAACCGAACCCCAATCCCAAATCAGCCCTTTCGCCGGC
ACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACC
CCGACAGTTCGAGCAGCAAAATTTTCCTGCAAAACCTTTCCCGCAATGATGACAAAAACAAACCGGGCCGCTATTCCCTC
AAACCCTTGAGTGAGAATGAGATTAAAAGTAAAGAGCCGCGTTTCAACGGAAGGCAGACCGTCATCCGATTGGATAGCGG
CGTACAGCTGATCAAACTGAATGGAAGCAAGGATGAGGTCGTCATTTTTGGAAACAACGGCAACAACGGCACTTTCGGCA
TTGTTAAGGAAGCGAACGTCAATCTTGAAGCCGACGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTCCCGAT
AATGACAATAAATTTAAATTAATTAACCAAAAACCAGACAGATACAGCCAAAGATACCGCATCCGCGAAAACGGCAATCG
CGATTTGGGCGACATCGTCAACAGCCCGATTGTCGCGGTCGGCGGGTATCTGGCAACTTCTGCCAACGACGGGATGGTGC
ATATCTTCAAAAAAACCGGCACGGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAG
GATATTGAAGGCAATGACTCCGACCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGG
CGTGGACGGCGGCTTTGTCTTGCGTCAAGTTAACTTAAACGGACAAGACCGCGTGTTTATGTTCGGCGCAATGGGCCTTG
GCGGCAGAGGCGCATACGCCTTGGATTTAAGCAAAATCAACGAAAAGTATCCAGCCGCCGCTCCCCTGTTTGATGTCAAA
AATGGCGATAAAAACGGCAAAAACGGCAAAAATCGCGTGGAAGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGG
CAAAATCCGCAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAACAAATTGCCAGCCAAGAAAATAAAA
CCGCGCTGTATGTGTATGATTTGAAAGACACCTTAGGTACGCCGATTGCAAAAATCGAAGTGAAGGGCGGCAAAGGCGGG
CTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGGAATAT
GTACCGCTTTGATTTGAGCAATTCCGATCCTAGTAAATGGTCTGTAAGCACTATTTTCGAAGGCGGGAAGCCGATTACCT
CCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGACCGAAGATGATGTA
CTCGATACGAAAGAACAATATATTTACGGTATCTTTGACGACGATAAGGCGGCGAATAATGTAAATGCAAGCCGCGGCGT
TTTGGGGAGCGGGCTGCTCGAGCAACACCTTACTCAGGAAAATAAAACATTATTCCTGAACAAGAGATCCGACGGTTCGG
GCAGCAAGGGCTGGGCGGTGAAATTGACAGGCGGACGGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTC
GTAACCATCCGCAAATATAAAGACGACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGC
ATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGAAGCCAATACGGCTGTCGCACAATATTCCGGCCATAAGAAAACCG
CCGGCGGCAAGTCCGTCCCCATAGGCTGCATGTGGAAAAACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAG
CCGGTTAATGTGCGTTATCTGGATGAAACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGG
TATAGACCCCGCCGGCAGGCGTCCCGGCAAAAACAACCGCTGCTTCTCCAAAAAAGGTGTGCGCACCCTGCTGATGAACG
ATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(509-847)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.564

100

0.74

Multiple sequence alignment