Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C7S03_RS00310 Genome accession   NZ_LT592163
Coordinates   53015..56167 (-) Length   1050 a.a.
NCBI ID   WP_144998510.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_W     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 48015..61167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7S03_RS00290 (WHOW_00049C) - 49576..49965 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  C7S03_RS00295 (WHOW_00050C) - 50128..50507 (-) 380 Protein_49 VOC family protein -
  C7S03_RS00300 (WHOW_00051C) carA 50561..51694 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  C7S03_RS00310 (WHOW_00052C) pilC 53015..56167 (-) 3153 WP_144998510.1 PilC family type IV pilus tip adhesin Machinery gene
  C7S03_RS00325 (WHOW_00053C) apbC 57609..58688 (-) 1080 WP_003699443.1 iron-sulfur cluster carrier protein ApbC -
  C7S03_RS00335 (WHOW_00055) - 59062..59571 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  C7S03_RS00345 (WHOW_00057) nadR 59912..60352 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  C7S03_RS00350 (WHOW_00058) hpaC 60467..60967 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1050 a.a.        Molecular weight: 115604.21 Da        Isoelectric Point: 9.9685

>NTDB_id=1144567 C7S03_RS00310 WP_144998510.1 53015..56167(-) (pilC) [Neisseria gonorrhoeae strain WHO_W]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGAMAQTHKYAIIMNERKQPEVKWETQYSQSALKDKGRERTFSHTSQKGRFN
ITHNFISFNNNDTLVSQQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIRTTRAGLAGYAYTGIRCGHARDCPKL
TYKTQFSFDNPDLAKTGDRLDRHTEPSRDNSPIYKLKDYPWLGVSFNLGAEGTAKDGRSSSRLISSFNEKNSNNNLVYTT
EGRDISLGNWQSESTAVAYYLNAKLHLLDKKEIKDITGKTVRLGVLKPSIDVKTQNTGFAGLLNFWSKWDIKDNGQIPVK
LGLPEVKAGRCTNKPNPNPKSKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPGRPGRYSL
AALNAQDIKSREPNFNSRQTVIRLPGGVYRIAPTRDRIVGLNGNDGKNDTFGIYKERLVTPDADEWAKVLLPWTVRYYGN
DDIFKTFNQPNSKTQNGKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATSANDGMVHLFKRNGTDQRGYELK
LSYIPGTMERKDIEGNDSDLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLSKIN
EKYPAAAPLFDVKNGDKNGKNGKNRVEVELGYTVGTPQIGKIRNGKYAAFLASGYAAKQIASQENKTALYVYDLENGSGS
LIKKIEAPSGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSDSNPSKWSVSTIFEGQRPITSAPAVSRLADKRVV
IFGTGSDLSESDVFNTDEQYIYGIFDDDKANVSVKVKDHMGDGLLKQNLTQENKTLFLTNNKASGGSADKGWVVKLREGE
RVTVKPTVVLRTAFVTIRKYKDDGCGAETAILGINTADGGALTPRSARPIVPDHNSVAQYSGHKKTSKGKSIPIGCMEKG
GKTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGI
KRLSWREVFF

Nucleotide


Download         Length: 3153 bp        

>NTDB_id=1144567 C7S03_RS00310 WP_144998510.1 53015..56167(-) (pilC) [Neisseria gonorrhoeae strain WHO_W]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGAGA
CTCAATATAGTCAATCAGCATTAAAGGACAAAGGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAGGCAGGTTCAAC
ATCACACACAATTTTATCTCATTCAACAATAACGATACCCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGC
CACCTACCTGCCGCCCTACGGCAAGGTTTCCGGCTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATTGGA
TTCGTACCACCCGGGCCGGGCTGGCAGGCTACGCCTACACCGGTATCCGTTGCGGACATGCCCGAGACTGTCCCAAACTT
ACCTATAAAACCCAATTTTCCTTCGATAATCCCGACTTGGCAAAAACAGGAGACAGGCTGGATAGGCACACAGAGCCAAG
CCGCGACAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCG
CCAAAGATGGCAGATCATCCAGCAGATTGATATCTTCTTTTAATGAAAAGAATAGTAATAACAACCTCGTCTATACCACG
GAAGGCCGCGATATTTCCTTGGGCAACTGGCAGAGCGAAAGTACCGCCGTGGCCTATTATCTGAACGCCAAGCTGCACCT
GCTGGACAAAAAAGAGATTAAAGATATCACCGGCAAAACAGTTCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGA
CACAAAATACGGGGTTTGCCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAG
CTCGGCCTGCCGGAAGTCAAAGCCGGGCGCTGCACCAACAAACCGAACCCCAATCCCAAATCCAAAGCCCCTTCGCCGGC
ACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACC
CCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGGCAGGCCCGGCCGGTATTCCCTC
GCCGCTTTGAATGCGCAGGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCCGATTGCCGGGCGG
CGTGTACCGGATCGCCCCGACTCGCGACAGGATCGTGGGTTTGAATGGCAATGACGGCAAAAACGACACTTTCGGCATCT
ACAAGGAAAGGTTAGTCACACCTGATGCCGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTACGGTAAT
GACGATATATTTAAAACATTCAACCAACCAAACAGCAAAACACAAAACGGCAAAAAACAATACAGCCAAAAATACCGCAT
CCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGCGGTCGGCGGGT
ATCTGGCAACTTCTGCCAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACGAGGCTACGAACTGAAG
CTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGCAATGACTCCGACCTCGCCAAAGAGCTGCGCACCTT
TGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACA
AGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTGGGCGGCAGAGGCGCATACGCCTTGGATTTAAGCAAAATCAAC
GAAAAGTATCCAGCCGCCGCTCCCCTGTTTGATGTCAAAAATGGCGATAAAAACGGCAAAAACGGCAAAAATCGCGTGGA
AGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAATCCGCAACGGCAAATACGCCGCCTTCCTCGCCTCCG
GTTATGCGGCTAAACAAATTGCCAGCCAAGAAAATAAAACCGCGCTGTATGTGTATGATTTGGAAAACGGCAGTGGTAGT
CTGATTAAAAAAATCGAAGCACCCAGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCAC
AGTCGATATCGCCTATGCCGGCGACCGGGGCGGGAATATGTACCGCTTTGATTTGAGCGATTCCAATCCTAGTAAATGGT
CTGTAAGCACTATTTTCGAAGGCCAGAGGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTCGTT
ATCTTCGGTACGGGCAGCGATTTGAGTGAAAGTGACGTATTCAATACGGACGAACAATATATTTACGGTATCTTTGACGA
CGATAAGGCGAATGTTAGTGTAAAGGTAAAAGACCACATGGGCGACGGGCTGCTCAAGCAAAACCTTACGCAGGAAAATA
AAACCTTGTTCCTGACAAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTGAGGGAAGGAGAA
CGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTAACCATCCGCAAATATAAAGACGACGGCTGCGGCGC
GGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATC
ACAATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCTCCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGGC
GGTAAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGA
TTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGT
GCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATC
AAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(520-862)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

69.311

100

0.699

Multiple sequence alignment