Detailed information
Bioinformatically predicted
Overview
| Name | pilK | Type | Machinery gene |
| Locus tag | C7S01_RS03100 | Genome accession | NZ_LT592155 |
| Coordinates | 519655..520263 (+) | Length | 202 a.a. |
| NCBI ID | WP_003690900.1 | Uniprot ID | A0AB74EBN2 |
| Organism | Neisseria gonorrhoeae strain WHO_X | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 515719..558642 | 519655..520263 | within | 0 |
Gene organization within MGE regions
Location: 515719..558642
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| C7S01_RS03075 (WHOX_00550) | dnaB | 515719..517125 (+) | 1407 | WP_003690896.1 | replicative DNA helicase | - |
| C7S01_RS03085 (WHOX_00551) | pilH | 517433..518098 (+) | 666 | WP_003690897.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| C7S01_RS03090 (WHOX_00552) | pilI | 518130..518738 (+) | 609 | WP_003690898.1 | type IV pilus modification protein PilV | Machinery gene |
| C7S01_RS03095 (WHOX_00553) | pilJ | 518735..519676 (+) | 942 | WP_003690899.1 | PilW family protein | Machinery gene |
| C7S01_RS03100 (WHOX_00554) | pilK | 519655..520263 (+) | 609 | WP_003690900.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| C7S01_RS03105 (WHOX_00555) | pilL | 520265..520738 (+) | 474 | WP_025455782.1 | PilX family type IV pilin | Machinery gene |
| C7S01_RS03120 (WHOX_00556C) | - | 521350..521795 (-) | 446 | Protein_523 | AzlC family ABC transporter permease | - |
| C7S01_RS03125 (WHOX_00557) | dut | 521961..522413 (+) | 453 | WP_003690909.1 | dUTP diphosphatase | - |
| C7S01_RS03130 (WHOX_00558) | dapC | 522491..523678 (+) | 1188 | WP_003690911.1 | succinyldiaminopimelate transaminase | - |
| C7S01_RS03135 (WHOX_00559) | yaaA | 523834..524613 (+) | 780 | WP_003690913.1 | peroxide stress protein YaaA | - |
| C7S01_RS03150 (WHOX_00562) | - | 525144..526340 (+) | 1197 | WP_003704323.1 | tyrosine-type recombinase/integrase | - |
| C7S01_RS03160 (WHOX_00563C) | - | 526696..526965 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| C7S01_RS03165 (WHOX_00564C) | - | 527160..527843 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| C7S01_RS14150 | - | 528124..528390 (-) | 267 | Protein_530 | hypothetical protein | - |
| C7S01_RS03175 (WHOX_00566C) | - | 528501..528716 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| C7S01_RS03180 (WHOX_00567C) | - | 528768..529259 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| C7S01_RS03185 (WHOX_00568C) | - | 529256..529438 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| C7S01_RS03190 (WHOX_00569C) | - | 529578..530264 (-) | 687 | WP_003691532.1 | phage replication initiation protein, NGO0469 family | - |
| C7S01_RS03195 (WHOX_00570C) | - | 530333..530494 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| C7S01_RS03200 (WHOX_00571C) | - | 530491..530769 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| C7S01_RS03205 (WHOX_00572C) | - | 530922..531254 (-) | 333 | WP_003691528.1 | hypothetical protein | - |
| C7S01_RS03210 (WHOX_00573C) | - | 531395..531682 (-) | 288 | WP_115067298.1 | hypothetical protein | - |
| C7S01_RS03215 (WHOX_00574C) | - | 531679..532155 (-) | 477 | WP_002255718.1 | DUF6948 domain-containing protein | - |
| C7S01_RS03220 (WHOX_00575C) | - | 532188..532388 (-) | 201 | WP_003692842.1 | hypothetical protein | - |
| C7S01_RS03225 (WHOX_00576C) | - | 532586..532999 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| C7S01_RS03230 (WHOX_00577C) | - | 532996..533457 (-) | 462 | WP_003687965.1 | helix-turn-helix domain-containing protein | - |
| C7S01_RS03235 (WHOX_00578C) | - | 533474..533911 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| C7S01_RS03240 (WHOX_00579C) | - | 534026..534742 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| C7S01_RS03245 (WHOX_00580) | - | 534817..535047 (+) | 231 | WP_020997318.1 | transcriptional regulator | - |
| C7S01_RS03250 (WHOX_00581) | - | 535127..535282 (+) | 156 | WP_047923772.1 | hypothetical protein | - |
| C7S01_RS03255 (WHOX_00582C) | - | 535259..535447 (-) | 189 | WP_047926457.1 | hypothetical protein | - |
| C7S01_RS03260 (WHOX_00583) | - | 535621..535848 (+) | 228 | WP_003691442.1 | helix-turn-helix domain-containing protein | - |
| C7S01_RS03265 (WHOX_00584) | - | 535845..536855 (+) | 1011 | WP_014580341.1 | helix-turn-helix domain-containing protein | - |
| C7S01_RS03270 (WHOX_00585) | - | 536867..537646 (+) | 780 | WP_025455804.1 | ATP-binding protein | - |
| C7S01_RS03275 | - | 537639..537887 (+) | 249 | WP_106158912.1 | hypothetical protein | - |
| C7S01_RS03280 (WHOX_00586) | - | 537963..538457 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| C7S01_RS03285 (WHOX_00587) | - | 538634..538783 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| C7S01_RS13635 (WHOX_00588) | - | 538812..539093 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| C7S01_RS03290 (WHOX_00589) | - | 539084..539521 (+) | 438 | WP_017147288.1 | RusA family crossover junction endodeoxyribonuclease | - |
| C7S01_RS03295 (WHOX_00590) | - | 539514..539819 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| C7S01_RS03300 (WHOX_00591) | - | 539816..540199 (+) | 384 | WP_003690918.1 | recombination protein NinB | - |
| C7S01_RS03305 (WHOX_00592) | - | 540190..540708 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| C7S01_RS03310 (WHOX_00593) | - | 540773..541195 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| C7S01_RS13640 (WHOX_00594) | - | 541195..541734 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| C7S01_RS03325 (WHOX_00595) | - | 541715..542989 (+) | 1275 | WP_014580143.1 | PBSX family phage terminase large subunit | - |
| C7S01_RS03330 (WHOX_00596) | - | 542974..545241 (+) | 2268 | WP_225577699.1 | hypothetical protein | - |
| C7S01_RS03335 (WHOX_00597) | - | 545478..546674 (+) | 1197 | WP_003690925.1 | hypothetical protein | - |
| C7S01_RS03340 (WHOX_00598) | - | 546671..547885 (+) | 1215 | WP_047954539.1 | hypothetical protein | - |
| C7S01_RS14290 (WHOX_00599) | - | 548088..553997 (+) | 5910 | WP_033909227.1 | PLxRFG domain-containing protein | - |
| C7S01_RS03355 (WHOX_00601) | - | 554623..555918 (+) | 1296 | WP_003690933.1 | DUF4043 family protein | - |
| C7S01_RS03360 (WHOX_00602) | - | 555973..556446 (+) | 474 | WP_003690936.1 | hypothetical protein | - |
| C7S01_RS03365 (WHOX_00603) | - | 556452..556937 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| C7S01_RS03370 (WHOX_00604) | - | 556934..557608 (+) | 675 | WP_003687998.1 | hypothetical protein | - |
| C7S01_RS03375 (WHOX_00605) | - | 557611..557760 (+) | 150 | WP_003706419.1 | hypothetical protein | - |
| C7S01_RS03380 (WHOX_00606C) | - | 557797..558642 (-) | 846 | WP_003690940.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 202 a.a. Molecular weight: 22023.05 Da Isoelectric Point: 7.5810
>NTDB_id=1144397 C7S01_RS03100 WP_003690900.1 519655..520263(+) (pilK) [Neisseria gonorrhoeae strain WHO_X]
MRKQNALTGIPTSEGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNDANEETFDNIVVKGKPTVEAVKRPCPAKSGKNSAGLCIDNKGMEYNKGVAGVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
MRKQNALTGIPTSEGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGEFQVLDLEYTA
DSKVTFSENCENGLCTAVNVRTNDANEETFDNIVVKGKPTVEAVKRPCPAKSGKNSAGLCIDNKGMEYNKGVAGVSKMPR
YIIEYLGVKNGQNVYRVTAKAWGKNANTVVVLQSYVGNNDEQ
Nucleotide
Download Length: 609 bp
>NTDB_id=1144397 C7S01_RS03100 WP_003690900.1 519655..520263(+) (pilK) [Neisseria gonorrhoeae strain WHO_X]
ATGCGCAAACAGAACGCTTTGACAGGAATCCCGACTTCTGAGGGACAGAGGGGGTTCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACATTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGATGCTAATGA
AGAGACTTTTGACAATATCGTGGTGAAAGGCAAGCCTACCGTTGAGGCCGTGAAGCGTCCTTGCCCTGCAAAGTCTGGCA
AAAATTCTGCCGGTCTGTGCATTGACAATAAAGGGATGGAATATAATAAAGGCGTGGCAGGCGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
ATGCGCAAACAGAACGCTTTGACAGGAATCCCGACTTCTGAGGGACAGAGGGGGTTCGCACTGTTTATCGTGCTGATGGT
GATGATAGTCGTGGCCTTTTTGGTTGTAACTGCCGCCCAGTCCTACAATACCGAACAGAGGATCAGTGCCAACGAATCAG
ACAGGAAATTGGCTTTGTCTTTAGCCGAGGCGGCTTTGAGGGAAGGCGAATTTCAGGTTTTGGATTTGGAATATACTGCG
GATAGTAAGGTTACATTTAGCGAAAACTGTGAAAACGGCCTGTGTACCGCAGTGAATGTACGGACAAATGATGCTAATGA
AGAGACTTTTGACAATATCGTGGTGAAAGGCAAGCCTACCGTTGAGGCCGTGAAGCGTCCTTGCCCTGCAAAGTCTGGCA
AAAATTCTGCCGGTCTGTGCATTGACAATAAAGGGATGGAATATAATAAAGGCGTGGCAGGCGTCAGCAAAATGCCGCGC
TATATTATCGAATATTTAGGCGTGAAGAACGGACAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAA
TACCGTGGTCGTCCTTCAATCTTATGTAGGCAATAATGATGAGCAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilK | Neisseria gonorrhoeae MS11 |
89.163 |
100 |
0.896 |