Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C7R99_RS00310 Genome accession   NZ_LT592153
Coordinates   52664..55834 (-) Length   1056 a.a.
NCBI ID   WP_144858261.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO_Z     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47664..60834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7R99_RS00280 (WHOZ_00048C) - 47829..48392 (-) 564 WP_002214615.1 ComF family protein -
  C7R99_RS00290 (WHOZ_00049C) - 49294..49683 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  C7R99_RS00295 (WHOZ_00050C) - 49846..50225 (-) 380 Protein_49 VOC family protein -
  C7R99_RS00300 (WHOZ_00051C) carA 50279..51412 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  C7R99_RS00310 (WHOZ_00052C) pilC 52664..55834 (-) 3171 WP_144858261.1 PilC family type IV pilus tip adhesin Machinery gene
  C7R99_RS00330 (WHOZ_00054C) apbC 57372..58451 (-) 1080 WP_106158884.1 iron-sulfur cluster carrier protein ApbC -
  C7R99_RS00340 (WHOZ_00056) - 58825..59334 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  C7R99_RS00350 (WHOZ_00058) nadR 59675..60115 (+) 441 WP_003694725.1 MarR family adhesin repressor NadR -
  C7R99_RS00355 (WHOZ_00059) hpaC 60230..60730 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1056 a.a.        Molecular weight: 116053.19 Da        Isoelectric Point: 9.8476

>NTDB_id=1144335 C7R99_RS00310 WP_144858261.1 52664..55834(-) (pilC) [Neisseria gonorrhoeae strain WHO_Z]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQTHKYAIIMNERKQPEVKWDGQYQKSQLREKDRERKFIYTNQKYWSGQ
QSNFISFNNNDTLVSQQSGTAVFGTATYLPPYGKVSGFDTDSLKGRANAAGWIRTTRPGLAGYAYTGIRCGHARDCPKLT
YKTRFSFDNPDLAKTGGRLDRHTESSRENSPIYKLKDYPWLGVSFNLGAEGTAKDGRSSSRLISSFDENNSNSNQNLVYT
TEGRDISLGNWQSESTAVAYYLNAKLHLLDKKGIEDITGKTVRLGVLKPSIDVKTQNTGFAGLLNFWSKWDIKDNGQIPV
KLGLPEVKAGRCTNKPNPNNNTKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPGRHS
LAALNARDIKSREPNFNSRQTVIRLPGGVYRIAPTRDRIVGLNGNDGKNDTFGIYKERLVTPDADEWAKVLLPWTVRYYG
NDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPIVAVDGYLATSANDGMVHLFKRNGTDQRGYEL
KLSYIPGTMPRQYFDNDTSALQDSDLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYAL
DLTKIDSNNLTGVSMFDVQNDKNNNKNDSNRVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKDIVSSDNTTALYVYDLGN
GSGSLIKKIEAPGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSDSNPDKWSVSTIFEGGKPITSAPAVSRLAD
KRVVIFGTGSDLSEEDVVGKDQQYIYGIFDDDKGTGTVKVTVQNGTGGGLLEQTLTKENNTLFLSNNKASGGSNGKGWVV
RLREGERVTVKPIVVLRTAFVTIRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPGDQVAQYSGHKTTSKGKSVPI
GCMEKDSKTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDIT
GPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3171 bp        

>NTDB_id=1144335 C7R99_RS00310 WP_144858261.1 52664..55834(-) (pilC) [Neisseria gonorrhoeae strain WHO_Z]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGATGGGC
AATATCAAAAATCACAATTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATACGAACCAGAAATACTGGTCGGGTCAA
CAAAGCAATTTTATCTCATTCAACAATAACGATACCCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCAC
CTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGTCTGAAAGGGCGCGCCAATGCCGCCGGTTGGATTC
GTACCACCCGGCCCGGGCTGGCAGGCTACGCCTACACCGGTATCCGTTGCGGACATGCCCGAGACTGTCCCAAACTTACC
TATAAAACCCGATTTTCCTTCGATAATCCCGACTTGGCAAAAACAGGAGGCAGGCTGGATAGGCACACAGAGTCAAGCCG
CGAAAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCGCCA
AAGATGGCAGATCATCCAGCAGATTGATATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTCTATACC
ACGGAAGGCCGCGATATTTCCTTGGGCAACTGGCAGAGCGAAAGTACCGCCGTGGCCTATTATCTGAACGCCAAGCTGCA
CCTGCTGGACAAAAAAGGGATTGAAGATATCACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGA
AGACACAAAATACGGGGTTTGCCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTC
AAGCTCGGCCTGCCGGAAGTCAAAGCCGGGCGCTGCACCAACAAACCGAACCCCAATAATAATACCAAAGCCCCTTCGCC
GGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCT
ACCCCGGCAGCTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGCCGGCATTCC
CTCGCCGCTTTGAATGCGCGGGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCGATTGCCGGG
CGGCGTGTACCGGATCGCCCCGACTCGCGACAGGATCGTGGGTTTGAATGGCAATGACGGCAAAAACGACACTTTCGGCA
TCTACAAGGAAAGGTTAGTCACACCTGATGCCGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTACGGT
AATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATACCG
CATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATTGTCGCGGTCGACG
GGTATTTGGCAACTTCTGCCAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACGAGGCTACGAACTG
AAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCCGCTCTCCAAGACTCCGACCTCGC
CAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCA
TTACAGATGACCAAGACAAGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTGGGCGGCAGAGGCGCGTATGCCTTG
GATTTGACCAAAATCGACAGCAACAACCTGACCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAAGAA
TGACAGTAATCGCGTGAAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCT
TCCTCGCTTCCGGTTATGCGGCTAAAGATATTGTCAGCAGCGATAATACAACCGCGCTGTATGTGTATGATTTGGGAAAC
GGCAGTGGTAGTCTGATTAAAAAAATCGAAGCACCCGGCGGCAAAGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGA
TTTGGACGGCACAGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCGATTCCAATC
CTGATAAATGGTCTGTAAGCACTATTTTCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGAC
AAACGCGTGGTTATCTTCGGCACGGGCAGCGATTTGAGTGAAGAGGATGTAGTCGGTAAGGATCAACAATATATTTACGG
TATCTTTGACGACGATAAGGGGACGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGCTGCTCGAGCAAA
CGCTTACGAAGGAAAATAACACCTTGTTCCTGAGCAATAATAAGGCATCCGGCGGATCGAACGGCAAAGGGTGGGTAGTG
AGATTGAGGGAAGGAGAACGCGTTACCGTCAAACCGATTGTGGTATTGCGTACCGCCTTTGTCACCATCCGTAGCTATAC
GGGTAATGACAAATGCGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCG
CGCGCCCGATTGTGCCGGGTGACCAGGTTGCGCAATATTCCGGCCATAAGACAACCTCCAAAGGCAAGTCCGTCCCTATA
GGTTGTATGGAAAAAGACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGCTACCTGGA
CGAAAAGAAAACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAAC
CCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACC
GGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(535-868)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

69.325

100

0.7

Multiple sequence alignment