Detailed information NTG1144191

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: E4V86_RS00325
• Genome accession: NZ_LT591910
• Coordinates: 52993..56169 (-)
• Length: 1058 a.a.
• NCBI ID: WP_144894332.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain WHO N
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 47993..61169

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E4V86_RS00300 (WHON_00051C)	-	49569..49958 (-)	390	WP_003687278.1	endonuclease domain-containing protein	-
E4V86_RS00305 (WHON_00052C)	-	50121..50500 (-)	380	Protein_49	VOC family protein	-
E4V86_RS00310 (WHON_00053C)	carA	50554..51687 (-)	1134	WP_003687283.1	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	-
E4V86_RS00320 (WHON_00054C)	-	52402..52686 (-)	285	WP_003692093.1	GIY-YIG nuclease family protein	-
E4V86_RS00325 (WHON_00055C)	pilC	52993..56169 (-)	3177	WP_144894332.1	PilC family type IV pilus tip adhesin	Machinery gene
E4V86_RS00345 (WHON_00056C)	apbC	58450..59529 (-)	1080	WP_047922916.1	iron-sulfur cluster carrier protein ApbC	-
E4V86_RS00355 (WHON_00058)	-	59903..60412 (+)	510	WP_003687293.1	protein disulfide oxidoreductase	-

Sequence

Protein

• Length: 1058 a.a.
• Molecular weight: 116600.01 Da
• Isoelectric Point: 9.9512

>NTDB_id=1144191 E4V86_RS00325 WP_144894332.1 52993..56169(-) (pilC) [Neisseria gonorrhoeae strain WHO N]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQTHKYAIIMNERKQPEVKWETQYSQSALKDKGRERTFSHTSQKGKFNI
THNFISFNNNDTLVSQQSGTAVFGTATYLPPYGKVSGFDADGLKKRNNAVNWIRTTRPGLAGYGYTGIRCGSTKDCPKLT
YKTRFSFDNTDLVETRGGLDRHTEPSRENSPIYKLKDYPWLGVSFNLGAEGTAKDGRSSSRLISSFDENNSNSNQNLVYT
TEGHRISLGNWQHETTAMAYYLNAKLHLLDKEKIKDITGKTVRLGVLKPSIDVKTQNTGLSGILNFWSKWDIKDNGQIPV
KLGLPEVKAGRCINKPNPNNNTKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPGRHS
LAALNTQDIKSREPNFNSRQTVIRLPGGVYRIAPTRDRIVGLNGNDGKNDTFGIYKDRLVTPEADEWAKVLLPWTVRYYG
NDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPIVAVGGYLATAANDGMVHIFKKNGGSDERSYN
LKLSYIPGTMPRQYFDNDTSALKDSTLAQELRTFAEKGYVGDRYGVDGGFVLRRITDDQDRQKHFFMFGAMGLGGRGAYA
LDLSKIDSSNLTGVSMFDVQNDKNNNNNKNDSNRVKLGYTVGTPQIGKTRSGKYAAFLASGYAAKDIGSGDNKTALYVYD
LENTSGKLIKKIEVKGGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSDSNPSKWSVSTIFEGQRPITSAPAVSR
LADKRVVIFGTGSDLSESDVFNTDEQYIYGIFDDDNRTVNVKVTNGTGGGLLEQVLTKENNTLFLSNNKASGGSADKGWV
VRLREGERVTVKPIVVLRTAFVTIRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPDHDSVAQYSGHKKTADGKSV
PIGCMWKNGKTACPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLD
ITGPMCGIKRLSWREVFF

Nucleotide

• Length: 3177 bp

>NTDB_id=1144191 E4V86_RS00325 WP_144894332.1 52993..56169(-) (pilC) [Neisseria gonorrhoeae strain WHO N]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGAGACTC
AATATAGTCAATCAGCATTAAAGGACAAAGGCAGGGAGCGGACATTTAGCCATACGAGCCAGAAAGGCAAGTTCAACATC
ACACACAATTTTATCTCATTCAACAATAACGATACCCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCAC
CTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATGCCGACGGGCTGAAAAAGCGCAACAATGCCGTCAATTGGATTC
GTACCACCCGGCCCGGGCTGGCAGGCTACGGCTACACCGGTATCCGTTGCGGAAGTACCAAAGACTGTCCCAAACTTACC
TATAAAACCCGATTTTCCTTCGATAATACCGACTTGGTAGAAACAAGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCG
CGAAAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCGCCA
AAGATGGCAGATCATCCAGCAGATTGATATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTCTATACG
ACAGAAGGCCACCGTATTTCCCTTGGCAACTGGCAGCACGAAACGACCGCCATGGCCTATTATCTGAACGCCAAGCTGCA
CCTGCTGGATAAAGAAAAGATTAAAGATATCACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGA
AGACACAAAATACGGGGCTTAGCGGCATTCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTC
AAGCTCGGCCTGCCGGAAGTCAAAGCCGGGCGCTGCATCAACAAACCGAACCCCAATAATAATACCAAAGCCCCTTCGCC
GGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGTAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCT
ACCCCGGCAGCTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGCCGGCATTCC
CTCGCCGCTTTGAATACGCAGGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCGATTGCCGGG
CGGCGTGTACCGGATCGCCCCGACTCGCGACAGGATCGTGGGTTTGAATGGCAATGACGGCAAAAACGACACTTTCGGCA
TCTACAAGGACAGGCTCGTCACACCTGAGGCCGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTACGGT
AATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATACCG
CATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATTGTCGCGGTCGGCG
GGTATTTGGCAACCGCCGCGAACGACGGGATGGTGCATATCTTCAAAAAAAACGGCGGCAGTGATGAACGCAGCTACAAT
CTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCCGCTCTCAAAGACTCCACCCT
CGCCCAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCC
GCATTACAGATGACCAGGACAGGCAAAAACATTTCTTTATGTTCGGCGCAATGGGCCTGGGCGGCAGAGGCGCGTATGCC
TTGGATTTAAGCAAAATCGACAGCAGCAACCTGACCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAA
CAATAAGAATGACAGTAATCGCGTGAAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCGCAGCGGCAAAT
ACGCCGCCTTCCTCGCTTCCGGTTATGCGGCTAAAGATATTGGCAGCGGCGATAATAAAACCGCGCTGTATGTGTATGAT
TTGGAAAACACCAGTGGTAAACTGATTAAAAAAATCGAAGTGAAGGGCGGCAAAGGCGGGCTTTCGTCCCCCACGCTGGT
GGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGGAATATGTACCGCTTTGATTTGAGCG
ATTCCAATCCTAGTAAATGGTCTGTAAGCACTATTTTCGAAGGCCAGAGGCCGATTACCTCCGCGCCCGCCGTTTCCCGA
CTGGCAGACAAACGCGTCGTTATCTTCGGTACGGGCAGCGATTTGAGTGAAAGTGACGTATTCAATACGGACGAACAATA
TATTTACGGTATCTTCGACGACGATAATAGGACGGTTAATGTAAAGGTAACAAACGGCACGGGAGGCGGGCTGCTCGAGC
AAGTGCTTACGAAGGAAAATAACACCTTGTTCCTGAGCAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTA
GTGAGATTGAGGGAAGGAGAACGCGTTACCGTCAAACCGATTGTGGTATTGCGTACCGCCTTTGTCACCATCCGTAGCTA
TACGGGTAATGACAAATGCGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAA
GCGCGCGCCCGATTGTGCCGGATCACGATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCGCCGACGGCAAGTCCGTC
CCTATAGGCTGTATGTGGAAAAACGGCAAAACCGCCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGCTA
CCTGGACGAAAAGAAAACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTA
AAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGAT
ATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

• Neisseria PilC beta-propeller domain (T4P_PilY1) (521-869)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Neisseria meningitidis A1493	69.512	100	0.7