Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C7S02_RS11255 Genome accession   NZ_LT591908
Coordinates   1880009..1883107 (+) Length   1032 a.a.
NCBI ID   WP_171000871.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO K     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1875009..1888107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7S02_RS11225 (WHOK_02066C) - 1875551..1876000 (-) 450 WP_003692085.1 CopD family copper resistance protein -
  C7S02_RS11230 (WHOK_02067C) waaA 1876041..1877312 (-) 1272 WP_010360974.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  C7S02_RS11235 (WHOK_02068C) gnd 1877375..1878823 (-) 1449 WP_003688061.1 decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase -
  C7S02_RS11240 (WHOK_02069C) - 1878903..1879166 (-) 264 WP_017147189.1 hypothetical protein -
  C7S02_RS11255 (WHOK_02070) pilC 1880009..1883107 (+) 3099 WP_171000871.1 PilC family type IV pilus tip adhesin Machinery gene
  C7S02_RS11270 (WHOK_02072) - 1883759..1884043 (+) 285 WP_003692093.1 GIY-YIG nuclease family protein -
  C7S02_RS11280 (WHOK_02073C) yccS 1884522..1886672 (-) 2151 WP_003699137.1 YccS family putative transporter -
  C7S02_RS11285 (WHOK_02074C) - 1886789..1888015 (-) 1227 WP_047926530.1 PilT/PilU family type 4a pilus ATPase -

Sequence

Protein


Download         Length: 1032 a.a.        Molecular weight: 113010.67 Da        Isoelectric Point: 10.0255

>NTDB_id=1144185 C7S02_RS11255 WP_171000871.1 1880009..1883107(+) (pilC) [Neisseria gonorrhoeae strain WHO K]
MNKTLKRRVFRHTALYTAILMFSHTGGGGQAQARDYAIIMNGRNQPEVKSNVPSSIKDKDRKRTFSHTSQTNWRGQQNNF
ISFDNSDELVSQQSGTAVFGTATYLPPYGKVSGFDTDRLKKRNNAVDWIRTTRIALAGYSYEGVVCRSGTGCPKLVYKTR
FSFDNPDLVKNAGKLDRYTDLSRENSPIYKLKDYPWLGVSFNLSSENTVKDSKLPNKLISSFSESNNNQTIVSTTEDHPI
SLGGSQREHTAVAYYLNAKLHLLDKKGIGDIAPGKTVRLGLLKPSIDVRKGNTRLSGILNFWSKWDIKDNGQIPVKLGLP
EVKAGRCINKPNPNPKSALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSKIFLQNLSRNDDKNKPGRYSLKPLSE
NEIKSKEPRFNGRQTVIRLDSGVQLIKLNGSKDEVVIFGNNGNNGTFGIVKEANVNLEADEWKKVLLPWTVRGPDNDNKF
KLINQKPDRYSQRYRIRENGNRDLGDIVNSPIVAVGGYLATSANDGMVHIFKKTGTDERSYNLKLSYIPGTMERKDIEGN
DSDLAKELRTFAEKGYVGDRYGVDGGFVLRQVNLNGQDRVFMFGAMGLGGRGAYALDLSKINEKYPAAAPLFDVKNGDKN
GKNGKNRVEVELGYTVGTPQIGKIRNGKYAAFLASGYAAKQIASQENKTALYVYDLKDTLGTPIAKIEVKGGKGGLSSPT
LVDKDLDGIVDIAYAGDRGGNMYRFDLSNSDPSKWSVSTIFEGGKPITSAPAVSRLADKRVVIFGTGSDLTEDDVLDTKE
QYIYGIFDDDKAANNVNASRGVLGSGLLEQHLTQENKTLFLNKRSDGSGSKGWAVKLTGGRRVTVKPTVVLRTAFVTIRK
YKDDGCGAETAILGINTADGGALTPRSARPIVPEANTAVAQYSGHKKTAGGKSVPIGCMWKNSKTVCPNGYVYDKPVNVR
YLDETETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3099 bp        

>NTDB_id=1144185 C7S02_RS11255 WP_171000871.1 1880009..1883107(+) (pilC) [Neisseria gonorrhoeae strain WHO K]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATACCGCCATATTGATGTTTTCCCATACCGGCGG
GGGGGGGCAGGCGCAAGCCCGTGACTACGCTATTATCATGAACGGGCGAAACCAGCCCGAGGTAAAGTCGAATGTGCCAT
CTTCAATAAAGGACAAAGACAGGAAGCGGACATTTAGCCATACGAGCCAGACAAACTGGCGGGGCCAACAAAACAATTTT
ATCTCATTCGACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCC
CTACGGCAAGGTTTCCGGTTTTGATACCGATAGGCTGAAAAAGCGCAACAATGCCGTTGATTGGATTCGTACCACCCGCA
TCGCGCTGGCAGGCTACAGCTACGAAGGTGTCGTATGCAGAAGCGGCACAGGCTGTCCCAAACTTGTCTATAAAACCCGA
TTTTCCTTCGATAATCCCGACTTGGTAAAAAATGCGGGCAAGCTGGATAGGTACACAGACCTAAGCCGCGAAAATTCGCC
CATTTACAAATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGAGCAGCGAGAATACCGTCAAAGATAGCAAAT
TACCCAACAAATTGATATCTTCTTTTAGTGAAAGCAATAATAATCAAACCATCGTCTCTACGACAGAAGATCACCCTATT
TCCCTTGGCGGCTCGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAAGG
GATTGGAGATATCGCGCCAGGCAAAACAGTGCGGTTGGGTCTCTTGAAGCCGAGCATCGATGTGCGGAAAGGAAATACGA
GGCTTAGCGGCATTCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCG
GAAGTCAAAGCAGGCCGCTGCATCAACAAACCGAACCCCAATCCCAAATCAGCCCTTTCGCCGGCACTGACCGCCCCCGC
GCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCA
GCAAAATTTTCCTGCAAAACCTTTCCCGCAATGATGACAAAAACAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTGAG
AATGAGATTAAAAGTAAAGAGCCGCGTTTCAACGGAAGGCAGACCGTCATCCGATTGGATAGCGGCGTACAGCTGATCAA
ACTGAATGGAAGCAAGGATGAGGTCGTCATTTTTGGAAACAACGGCAACAACGGCACTTTCGGCATTGTTAAGGAAGCGA
ACGTCAATCTTGAAGCCGACGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTCCCGATAATGACAATAAATTT
AAATTAATTAACCAAAAACCAGACAGATACAGCCAAAGATACCGCATCCGCGAAAACGGCAATCGCGATTTGGGCGACAT
CGTCAACAGCCCGATTGTCGCGGTCGGCGGGTATCTGGCAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAAAAA
CCGGCACGGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGCAAT
GACTCCGACCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTT
TGTCTTGCGTCAAGTTAACTTAAACGGACAAGACCGCGTGTTTATGTTCGGCGCAATGGGCCTTGGCGGCAGAGGCGCAT
ACGCCTTGGATTTAAGCAAAATCAACGAAAAGTATCCAGCCGCCGCTCCCCTGTTTGATGTCAAAAATGGCGATAAAAAC
GGCAAAAACGGCAAAAATCGCGTGGAAGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAATCCGCAACGG
CAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAACAAATTGCCAGCCAAGAAAATAAAACCGCGCTGTATGTGT
ATGATTTGAAAGACACCTTAGGTACGCCGATTGCAAAAATCGAAGTGAAGGGCGGCAAAGGCGGGCTTTCGTCCCCCACG
CTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGGAATATGTACCGCTTTGATTT
GAGCAATTCCGATCCTAGTAAATGGTCTGTAAGCACTATTTTCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCGTTT
CCCGACTGGCAGACAAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGACCGAAGATGATGTACTCGATACGAAAGAA
CAATATATTTACGGTATCTTTGACGACGATAAGGCGGCGAATAATGTAAATGCAAGCCGCGGCGTTTTGGGGAGCGGGCT
GCTCGAGCAACACCTTACTCAGGAAAATAAAACATTATTCCTGAACAAGAGATCCGACGGTTCGGGCAGCAAGGGCTGGG
CGGTGAAATTGACAGGCGGACGGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTAACCATCCGCAAA
TATAAAGACGACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAG
CGCGCGCCCGATTGTGCCGGAAGCCAATACGGCTGTCGCACAATATTCCGGCCATAAGAAAACCGCCGGCGGCAAGTCCG
TCCCCATAGGCTGCATGTGGAAAAACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGT
TATCTGGATGAAACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGCCGG
CAGGCGTCCCGGCAAAAACAACCGCTGCTTCTCCAAAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGG
ATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(504-842)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.296

100

0.738

Multiple sequence alignment