Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C7S02_RS00325 Genome accession   NZ_LT591908
Coordinates   52696..55797 (-) Length   1033 a.a.
NCBI ID   WP_115067537.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO K     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47696..60797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7S02_RS00285 (WHOK_00048C) - 47787..48350 (-) 564 WP_002214615.1 ComF family protein -
  C7S02_RS00295 (WHOK_00049C) - 49252..49641 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  C7S02_RS00300 (WHOK_00050C) - 49804..50183 (-) 380 Protein_49 VOC family protein -
  C7S02_RS00305 (WHOK_00051C) carA 50237..51370 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  C7S02_RS00325 (WHOK_00052C) pilC 52696..55797 (-) 3102 WP_115067537.1 PilC family type IV pilus tip adhesin Machinery gene
  C7S02_RS00350 (WHOK_00053C) apbC 57239..58318 (-) 1080 WP_003699443.1 iron-sulfur cluster carrier protein ApbC -
  C7S02_RS00360 (WHOK_00055) - 58692..59201 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  C7S02_RS00370 (WHOK_00057) nadR 59542..59982 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  C7S02_RS00375 (WHOK_00058) hpaC 60097..60597 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1033 a.a.        Molecular weight: 113054.79 Da        Isoelectric Point: 10.0255

>NTDB_id=1144144 C7S02_RS00325 WP_115067537.1 52696..55797(-) (pilC) [Neisseria gonorrhoeae strain WHO K]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQARDYAIIMNGRNQPEVKSNVPSSIKDKDRKRTFSHTSQTNWRGQQNN
FISFDNSDELVSQQSGTAVFGTATYLPPYGKVSGFDTDRLKKRNNAVDWIRTTRIALAGYSYEGVVCRSGTGCPKLVYKT
RFSFDNPDLVKNAGKLDRYTDLSRENSPIYKLKDYPWLGVSFNLSSENTVKDSKLPNKLISSFSESNNNQTIVSTTEDHP
ISLGGSQREHTAVAYYLNAKLHLLDKKGIGDIAPGKTVRLGLLKPSIDVRKGNTRLSGILNFWSKWDIKDNGQIPVKLGL
PEVKAGRCINKPNPNPKSALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSKIFLQNLSRNDDKNKPGRYSLKPLS
ENEIKSKEPRFNGRQTVIRLDSGVQLIKLNGSKDEVVIFGNNGNNGTFGIVKEANVNLEADEWKKVLLPWTVRGPDNDNK
FKLINQKPDRYSQRYRIRENGNRDLGDIVNSPIVAVGGYLATSANDGMVHIFKKTGTDERSYNLKLSYIPGTMERKDIEG
NDSDLAKELRTFAEKGYVGDRYGVDGGFVLRQVNLNGQDRVFMFGAMGLGGRGAYALDLSKINEKYPAAAPLFDVKNGDK
NGKNGKNRVEVELGYTVGTPQIGKIRNGKYAAFLASGYAAKQIASQENKTALYVYDLKDTLGTPIAKIEVKGGKGGLSSP
TLVDKDLDGIVDIAYAGDRGGNMYRFDLSNSDPSKWSVSTIFEGGKPITSAPAVSRLADKRVVIFGTGSDLTEDDVLDTK
EQYIYGIFDDDKAANNVNASRGVLGSGLLEQHLTQENKTLFLNKRSDGSGSKGWAVKLTGGRRVTVKPTVVLRTAFVTIR
KYKDDGCGAETAILGINTADGGALTPRSARPIVPEANTAVAQYSGHKKTAGGKSVPIGCMWKNSKTVCPNGYVYDKPVNV
RYLDETETDGFSTTADGDAGGSGIDPAGRRPGKNNRCFSKKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3102 bp        

>NTDB_id=1144144 C7S02_RS00325 WP_115067537.1 52696..55797(-) (pilC) [Neisseria gonorrhoeae strain WHO K]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAGCCCGTGACTACGCTATTATCATGAACGGGCGAAACCAGCCCGAGGTAAAGTCGAATGTGC
CATCTTCAATAAAGGACAAAGACAGGAAGCGGACATTTAGCCATACGAGCCAGACAAACTGGCGGGGCCAACAAAACAAT
TTTATCTCATTCGACAATAGCGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCC
GCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGGCTGAAAAAGCGCAACAATGCCGTTGATTGGATTCGTACCACCC
GCATCGCGCTGGCAGGCTACAGCTACGAAGGTGTCGTATGCAGAAGCGGCACAGGCTGTCCCAAACTTGTCTATAAAACC
CGATTTTCCTTCGATAATCCCGACTTGGTAAAAAATGCGGGCAAGCTGGATAGGTACACAGACCTAAGCCGCGAAAATTC
GCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTATCTTTCAATTTGAGCAGCGAGAATACCGTCAAAGATAGCA
AATTACCCAACAAATTGATATCTTCTTTTAGTGAAAGCAATAATAATCAAACCATCGTCTCTACGACAGAAGATCACCCT
ATTTCCCTTGGCGGCTCGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAA
AGGGATTGGAGATATCGCGCCAGGCAAAACAGTGCGGTTGGGTCTCTTGAAGCCGAGCATCGATGTGCGGAAAGGAAATA
CGAGGCTTAGCGGCATTCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTG
CCGGAAGTCAAAGCAGGCCGCTGCATCAACAAACCGAACCCCAATCCCAAATCAGCCCTTTCGCCGGCACTGACCGCCCC
CGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGA
GCAGCAAAATTTTCCTGCAAAACCTTTCCCGCAATGATGACAAAAACAAACCGGGCCGCTATTCCCTCAAACCCTTGAGT
GAGAATGAGATTAAAAGTAAAGAGCCGCGTTTCAACGGAAGGCAGACCGTCATCCGATTGGATAGCGGCGTACAGCTGAT
CAAACTGAATGGAAGCAAGGATGAGGTCGTCATTTTTGGAAACAACGGCAACAACGGCACTTTCGGCATTGTTAAGGAAG
CGAACGTCAATCTTGAAGCCGACGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGGGGTCCCGATAATGACAATAAA
TTTAAATTAATTAACCAAAAACCAGACAGATACAGCCAAAGATACCGCATCCGCGAAAACGGCAATCGCGATTTGGGCGA
CATCGTCAACAGCCCGATTGTCGCGGTCGGCGGGTATCTGGCAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAA
AAACCGGCACGGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGC
AATGACTCCGACCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGG
CTTTGTCTTGCGTCAAGTTAACTTAAACGGACAAGACCGCGTGTTTATGTTCGGCGCAATGGGCCTTGGCGGCAGAGGCG
CATACGCCTTGGATTTAAGCAAAATCAACGAAAAGTATCCAGCCGCCGCTCCCCTGTTTGATGTCAAAAATGGCGATAAA
AACGGCAAAAACGGCAAAAATCGCGTGGAAGTGGAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAATCCGCAA
CGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAACAAATTGCCAGCCAAGAAAATAAAACCGCGCTGTATG
TGTATGATTTGAAAGACACCTTAGGTACGCCGATTGCAAAAATCGAAGTGAAGGGCGGCAAAGGCGGGCTTTCGTCCCCC
ACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGGAATATGTACCGCTTTGA
TTTGAGCAATTCCGATCCTAGTAAATGGTCTGTAAGCACTATTTTCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCG
TTTCCCGACTGGCAGACAAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGACCGAAGATGATGTACTCGATACGAAA
GAACAATATATTTACGGTATCTTTGACGACGATAAGGCGGCGAATAATGTAAATGCAAGCCGCGGCGTTTTGGGGAGCGG
GCTGCTCGAGCAACACCTTACTCAGGAAAATAAAACATTATTCCTGAACAAGAGATCCGACGGTTCGGGCAGCAAGGGCT
GGGCGGTGAAATTGACAGGCGGACGGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTAACCATCCGC
AAATATAAAGACGACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAG
AAGCGCGCGCCCGATTGTGCCGGAAGCCAATACGGCTGTCGCACAATATTCCGGCCATAAGAAAACCGCCGGCGGCAAGT
CCGTCCCCATAGGCTGCATGTGGAAAAACAGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTG
CGTTATCTGGATGAAACGGAAACAGACGGATTTTCAACGACGGCGGACGGCGATGCGGGCGGCAGCGGTATAGACCCCGC
CGGCAGGCGTCCCGGCAAAAACAACCGCTGCTTCTCCAAAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCT
TGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(505-843)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.581

100

0.741

Multiple sequence alignment