Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C7R98_RS00345 Genome accession   NZ_LT591904
Coordinates   53289..56450 (-) Length   1053 a.a.
NCBI ID   WP_106176356.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO M     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 48289..61450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7R98_RS00305 (WHOM_00051C) - 49553..49942 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  C7R98_RS00310 (WHOM_00052C) - 50105..50484 (-) 380 Protein_49 VOC family protein -
  C7R98_RS00315 (WHOM_00053C) carA 50538..51671 (-) 1134 WP_003694721.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  C7R98_RS00345 (WHOM_00054C) pilC 53289..56450 (-) 3162 WP_106176356.1 PilC family type IV pilus tip adhesin Machinery gene
  C7R98_RS00355 (WHOM_00055C) apbC 57283..58362 (-) 1080 WP_003699443.1 iron-sulfur cluster carrier protein ApbC -
  C7R98_RS00365 (WHOM_00057) - 58736..59245 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  C7R98_RS00375 (WHOM_00059) nadR 59586..60026 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  C7R98_RS00380 (WHOM_00060) hpaC 60141..60641 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  C7R98_RS00385 (WHOM_00061) murU 60657..61352 (+) 696 WP_003687300.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -

Sequence

Protein


Download         Length: 1053 a.a.        Molecular weight: 115989.04 Da        Isoelectric Point: 9.6738

>NTDB_id=1144094 C7R98_RS00345 WP_106176356.1 53289..56450(-) (pilC) [Neisseria gonorrhoeae strain WHO M]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAMAQTHKYAIIMNERKQPEVKWDGQYQKSQLREKDGERKFIYTNQKHWSGQ
QSNFISFNNNDTLVSQQSGTAVFGTATYLPPYGKVSGFDTDSLKGRANAAGWIRTTRPGLAGYAYTGIRCGHARDCPKLT
YKTRFSFDNPDLAKTGGRLDRHTESSRENSPIYKLKDYPWLGVSFNLGAEGTAKDGRSSSRLISSFDENNSNSNQNLVYT
TEGRDISLGNWQSESTAVAYYLNAKLHLLDKKKIKDITGKTVQLGVLKPSIDVKTQNTGFAGLLNFWSKWDIKDNGQIPV
KLGLPEVKAGRCTNKPNPNNNTKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPARPGRHS
LAALNARDIKSREPNFNSRQTVIRLPGGVYRIAPTRDRIVGLNGNDGKNDTFGIYKERLVTPDADEWAKVLLPWTVRYYG
NDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPIVAVDGYLATSANDGMVHLFKRNGTDQRGYEL
KLSYIPGTMPRQYFDNDTSALQDSDLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDRQKHFFMFGAMGFGGRGAYAL
DLSKIDSSNLTGVSMFDVQNDKNNNKNDSNRVKLGYTVGTPQIGKTQNGTYSAFLASGYAAKDIVSSDNTTALYVYDLEN
TLGTPIAKIDVPGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSDSDSSKWSVSTIFEGGKPITSAPAVSRLAD
KRVVIFGTGSDLSEEDVLNTDEQYIYGIFDDDEGTVNVKVTNGTGGGLLEQTLTKENNTLFLSNNKASGGSADKGWVVKL
MDGERVTVKPTVVLRTAFVTIRKYTDTDKCGAQTAILGINTADGGALTPRSARPIVPDNQVAQYSGHQKMNGKSIPIGCM
WKNGKTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPM
CGIKRLSWREVFF

Nucleotide


Download         Length: 3162 bp        

>NTDB_id=1144094 C7R98_RS00345 WP_106176356.1 53289..56450(-) (pilC) [Neisseria gonorrhoeae strain WHO M]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGATGGCGCAAACCCATAAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGATGGGC
AATATCAAAAATCACAATTAAGGGAAAAAGACGGGGAACGCAAATTTATCTATACGAACCAGAAACACTGGTCGGGTCAA
CAAAGCAATTTTATCTCATTCAACAATAACGATACCCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCAC
CTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATACCGATAGTCTGAAAGGGCGCGCCAATGCCGCCGGTTGGATTC
GTACCACCCGGCCCGGGCTGGCAGGCTACGCCTACACCGGTATCCGTTGCGGACATGCCCGAGACTGTCCCAAACTTACC
TATAAAACCCGATTTTCCTTCGATAATCCCGACTTGGCAAAAACAGGAGGCAGGCTGGATAGGCACACAGAGTCAAGCCG
CGAAAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCGCCA
AAGATGGCAGATCATCCAGCAGATTGATATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTCTATACC
ACGGAAGGCCGCGATATTTCCTTGGGCAACTGGCAGAGCGAAAGTACCGCCGTGGCCTATTATCTGAACGCCAAGCTGCA
CCTGCTGGACAAAAAAAAGATTAAAGATATCACCGGCAAAACAGTGCAGTTGGGTGTCTTGAAGCCGAGCATCGATGTGA
AGACACAAAATACGGGGTTTGCCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTC
AAGCTCGGCCTGCCGGAAGTCAAAGCCGGGCGCTGCACCAACAAACCGAACCCCAATAATAATACCAAAGCCCCTTCGCC
GGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCT
ACCCCGGCAGCTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGCCCGGCCCGGCCGGCATTCC
CTCGCCGCTTTGAATGCGCGGGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCGATTGCCGGG
CGGCGTGTACCGGATCGCCCCGACTCGCGACAGGATCGTGGGTTTGAATGGCAATGACGGCAAAAACGACACTTTCGGCA
TCTACAAGGAAAGGTTAGTCACACCTGATGCCGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTACGGT
AATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATACCG
CATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATTGTCGCGGTCGACG
GGTATTTGGCAACTTCTGCCAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACGAGGCTACGAACTG
AAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCCGCTCTCCAAGACTCCGACCTCGC
CAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCA
TTACAGATGACCAGGACAGGCAAAAACATTTCTTTATGTTTGGTGCGATGGGTTTTGGCGGCAGAGGCGCGTATGCCTTG
GATTTAAGCAAAATCGACAGCAGCAACCTGACCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAAGAA
TGACAGTAATCGCGTGAAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCACATACTCCGCCT
TCCTCGCCTCCGGTTATGCGGCTAAAGATATTGTCAGCAGCGATAATACAACCGCGCTGTATGTGTATGATTTGGAAAAC
ACCTTAGGTACGCCGATTGCAAAAATCGATGTGCCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGA
TTTGGACGGCACGGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCGATTCCGATT
CTAGTAAATGGTCTGTAAGCACTATTTTCGAAGGCGGGAAGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGAC
AAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGAGTGAAGAGGATGTACTGAATACGGACGAACAATATATTTACGG
TATCTTTGACGACGATGAGGGGACGGTTAATGTAAAGGTAACAAACGGCACGGGAGGCGGGCTGCTCGAGCAAACGCTTA
CGAAGGAAAATAACACCTTGTTCCTGAGCAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTG
ATGGACGGAGAACGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTGACCATCCGGAAATATACGGATAC
GGACAAATGTGGCGCGCAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCC
CGATTGTGCCGGATAACCAGGTTGCGCAATATTCCGGCCATCAGAAAATGAACGGCAAGTCCATCCCCATAGGCTGCATG
TGGAAAAACGGCAAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTACCTGGACGAAAAGAA
AACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCA
ATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATG
TGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(535-866)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

69.332

100

0.7

Multiple sequence alignment