Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C7S07_RS00340 Genome accession   NZ_LT591898
Coordinates   53005..56148 (-) Length   1047 a.a.
NCBI ID   WP_144999776.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain WHO G     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 48005..61148
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7S07_RS00315 (WHOG_00051C) - 49581..49970 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  C7S07_RS00320 (WHOG_00052C) - 50133..50512 (-) 380 Protein_49 VOC family protein -
  C7S07_RS00325 (WHOG_00053C) carA 50566..51699 (-) 1134 WP_003687283.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  C7S07_RS00335 (WHOG_00054C) - 52414..52698 (-) 285 WP_003692093.1 GIY-YIG nuclease family protein -
  C7S07_RS00340 (WHOG_00055C) pilC 53005..56148 (-) 3144 WP_144999776.1 PilC family type IV pilus tip adhesin Machinery gene
  C7S07_RS13145 - 56297..56482 (-) 186 WP_172617246.1 hypothetical protein -
  C7S07_RS00365 (WHOG_00056C) apbC 57881..58960 (-) 1080 WP_047924177.1 iron-sulfur cluster carrier protein ApbC -
  C7S07_RS00375 (WHOG_00058) - 59334..59843 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  C7S07_RS00385 (WHOG_00060) nadR 60184..60624 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -

Sequence

Protein


Download         Length: 1047 a.a.        Molecular weight: 114641.85 Da        Isoelectric Point: 9.9181

>NTDB_id=1143999 C7S07_RS00340 WP_144999776.1 53005..56148(-) (pilC) [Neisseria gonorrhoeae strain WHO G]
MNKTLKRQVFRHTALYAAILMFSHTGGGGGAMAQTRKYAIIMNERNQPEVRWEGSYSTLREKDRKREYTHHKYPRGGSSV
SFNNNDELVSQQSGTAVFGTATYLPPYGKVSGFDTDSLKGRANAVDWIRTTRIALAGYSYAGVVCNSTTGCPKLVYKTRF
SFDNPDLAKTGGRLNRHTEPSRDNSPIYKLKDYPWLGVSFNLGAEGTAKDGKVTNKLVSSFDENNSNSNQNLVYTTEGHN
ISLGNWQRESTAMAYYLNAKLHLLDKKGIKDITSKTVRLGVLKPSIDVRKGNTGLSGILSFWAKWDIKDNGQIPVKLGLP
EVKAGRCINKPNPNNNTKAPSPALTAPALWFGPGQDGKVQMYSASVSTYPGSSSSRIFLQELKTKTDPGRPGRHSLAALD
TQNIKSREPNFNSRQTVIRLPGGVYKINPVKNGGRVAGFNGNDGKNDTFGIYKDRLVTPEADEWSEVLLPWTARYYGNDD
IFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATSANDGMVHIFKKTGTDQRGYELKLS
YIPGTMERKDIENQDSTLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLSKIDSS
NLTGVSMFDVQNDKNNNNNKNDNNRVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKQIASQENKTALYVYDLGNTLGTPI
AKIDVPGGKGGLSSPTLVDKNLDGTVDIAYAGDRGGSMYRFDLSGDNPSKWTVRTIFQGTKPITSAPAVSRLADKRVVIF
GTGSDLSEEDVVGTDQQYIYGIFDDDKGTVKVTVQNGTGGGLLEQTLTKESNTLFLSNNKASGGSNGEGWVVKLGEGERV
TVKPTVVLRTAFVTIRKYTGNDKCDAQTAILGINTADGGALTPRSARPIVPGDQVAQYSGHQKMNGKSVPIGCMWKNGKT
VCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGIKRL
SWREVFF

Nucleotide


Download         Length: 3144 bp        

>NTDB_id=1143999 C7S07_RS00340 WP_144999776.1 53005..56148(-) (pilC) [Neisseria gonorrhoeae strain WHO G]
ATGAATAAAACTTTGAAACGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCCGTAAATACGCTATTATCATGAACGAACGAAATCAGCCGGAGGTAAGGTGGGAGG
GTTCATATTCAACCTTAAGGGAAAAAGACAGGAAGCGCGAATATACTCATCATAAGTACCCACGAGGAGGAAGCTCTGTC
TCATTCAACAATAACGATGAGCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTA
CGGCAAGGTTTCCGGTTTTGATACCGATAGTCTGAAAGGGCGCGCCAATGCCGTTGATTGGATTCGTACCACCCGCATCG
CGCTGGCAGGCTACAGCTACGCCGGTGTCGTATGCAACAGCACCACAGGCTGTCCCAAACTTGTCTATAAAACCCGATTT
TCCTTCGATAATCCCGACTTGGCAAAAACAGGAGGCAGGCTGAATAGGCACACAGAGCCAAGCCGCGACAATTCGCCCAT
TTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCGCCAAAGATGGTAAGGTAA
CCAACAAATTGGTATCTTCTTTTGATGAAAACAATAGTAATAGTAATCAAAACCTCGTCTATACCACGGAAGGCCACAAT
ATTTCCTTGGGCAACTGGCAGCGCGAAAGTACCGCCATGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGACAAAAA
AGGGATTAAAGATATCACCAGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGCGGAAAGGAAATACGG
GGCTTAGCGGCATTCTATCTTTTTGGGCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAGCTCGGCCTGCCG
GAAGTCAAAGCAGGCCGCTGCATCAACAAACCGAACCCCAATAATAATACCAAAGCCCCTTCGCCGGCACTGACCGCCCC
CGCGCTGTGGTTCGGACCCGGGCAAGATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACCCCGGCAGCTCGA
GCAGCCGCATCTTCCTCCAAGAGCTGAAAACTAAAACCGACCCCGGCAGGCCCGGCCGGCATTCCCTCGCCGCTTTGGAT
ACGCAGAACATCAAAAGCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTGATCCGATTGCCGGGCGGCGTGTACAAGAT
CAACCCGGTCAAGAACGGCGGCCGGGTCGCGGGTTTTAATGGCAATGACGGCAAAAACGACACTTTCGGCATCTACAAGG
ACAGGCTCGTCACACCTGAGGCCGACGAGTGGAGCGAAGTGCTGCTGCCTTGGACGGCTCGGTATTACGGTAATGACGAT
ATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATACCGCATCCGCAC
AAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGCGGTCGGCGGGTATCTGG
CAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAAAAACCGGCACAGACCAACGAGGCTACGAACTGAAGCTCAGC
TACATCCCCGGTACGATGGAGCGTAAGGATATTGAAAACCAAGACTCCACCCTCGCCAAAGAGCTGCGCACCTTTGCCGA
AAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACAAGCAAA
AACATTTCTTTATGTTTGGTGCGATGGGCCTTGGCGGCAGAGGCGCGTATGCCTTGGATTTAAGCAAAATCGACAGCAGC
AACCTGACCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAACAATAAGAATGACAATAATCGCGTGAA
ATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATG
CGGCTAAACAAATTGCCAGCCAAGAAAATAAAACCGCGCTGTATGTGTATGATTTGGGAAACACCTTAGGTACGCCGATT
GCAAAAATCGATGTGCCCGGCGGCAAAGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAAATTTGGACGGCACGGTCGA
TATCGCCTATGCCGGCGACCGGGGCGGTAGTATGTACCGCTTTGATTTGAGCGGCGACAATCCGTCCAAATGGACTGTAC
GCACTATTTTCCAAGGCACAAAACCGATTACTTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTGGTCATCTTC
GGCACGGGCAGCGATTTGAGTGAAGAGGATGTAGTCGGTACGGATCAACAATATATTTACGGTATCTTTGACGACGATAA
GGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGCTGCTCGAGCAAACGCTTACGAAGGAAAGTAACACCT
TGTTCCTGAGCAATAATAAGGCATCCGGCGGATCGAACGGCGAAGGGTGGGTAGTGAAATTGGGGGAAGGAGAACGCGTT
ACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTGACCATCCGGAAATATACGGGTAATGACAAATGCGACGCGCA
AACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGGTGACC
AGGTTGCGCAATATTCCGGCCATCAGAAAATGAACGGCAAGTCCGTCCCCATAGGCTGCATGTGGAAAAACGGCAAAACC
GTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTACCTGGACGAAAAGAAAACAGACGATTTCCCCGT
CACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCG
GAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTA
AGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(518-860)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

69.915

100

0.706

Multiple sequence alignment