Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C7S05_RS00310 Genome accession   NZ_LT591897
Coordinates   52273..55395 (-) Length   1040 a.a.
NCBI ID   WP_144996877.1    Uniprot ID   A0AB74ED87
Organism   Neisseria gonorrhoeae strain WHO F     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 47273..60395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7S05_RS00275 (WHOF_00049C) - 47283..47816 (-) 534 WP_003692498.1 hypothetical protein -
  C7S05_RS00280 (WHOF_00050C) - 48536..48925 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  C7S05_RS00285 (WHOF_00051C) - 49088..49467 (-) 380 Protein_48 VOC family protein -
  C7S05_RS00290 (WHOF_00052C) carA 49521..50654 (-) 1134 WP_047924203.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  C7S05_RS00310 (WHOF_00053C) pilC 52273..55395 (-) 3123 WP_144996877.1 PilC family type IV pilus tip adhesin Machinery gene
  C7S05_RS13520 (WHOF_00054C) - 55530..55718 (-) 189 WP_154236026.1 hypothetical protein -
  C7S05_RS00325 (WHOF_00055C) apbC 56916..57995 (-) 1080 WP_047924177.1 iron-sulfur cluster carrier protein ApbC -
  C7S05_RS00335 (WHOF_00057) - 58362..58871 (+) 510 WP_003687293.1 protein disulfide oxidoreductase -
  C7S05_RS00345 (WHOF_00059) nadR 59212..59652 (+) 441 WP_003687296.1 MarR family adhesin repressor NadR -
  C7S05_RS00350 (WHOF_00060) hpaC 59767..60267 (+) 501 WP_003687298.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1040 a.a.        Molecular weight: 114282.70 Da        Isoelectric Point: 9.7824

>NTDB_id=1143949 C7S05_RS00310 WP_144996877.1 52273..55395(-) (pilC) [Neisseria gonorrhoeae strain WHO F]
MNKTLKRRVFRHTALYAAILMFSHTGGGGAQAQTRKYAIIMNERKQPEVKWEGQYSQSTLKDKGRERTFSHTSQRNWNGQ
QNNFISFNNSDELVSRQSGTAVFGTATYLPPYGKVSGFDADGLKKRGNAVNWIRTTRPGLAGYIYTGVICRDTGQCPELV
YETKFSFDGIDLAKGGNRKLDRHPDPSRENLPIYKLKDHPWLGVSFNLGGEGTAKDGRSSSRWISSFSEDNNNQTIVFTT
RGHPISLGDWQRESTAMAYYLDAKLHLLDKTQIENIAPGKTVNLGILRPRVEAKVRRKWDLLNFWAKWDIKDTGQIPVKL
GLPEVKAGRCINKPNPNPKSALSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTKTDPARPGRHSLAA
LNAQDIKSREPNFNSRQTVIRLPGGVYQIAPGNSGRVAGFNGNDGKNDTFGIYKDRLVTPEADEWSEVLLPWTARYYGND
DIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATSANDGMVHIFKKTGTDQRGYELKL
SYIPGTMERKDIENQDSTLAKELRTFAEKGYVGDRYGVDGGFVLRSITDDQDRQKHFFMFGAMGLGGRGAYALDLSKIDS
NPVGVSMFDVQNESKNNGVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKQIASQENKTALYVYDLKDTLGTPIAKIEAPG
GKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSNSDSSKWSAKVIFEGDKPITSAPAVSRLADKRVVIFGTGSDLS
EEDVLNADEQYIYGIFDDDKGTVNVKVTNGTGGGLLEQVLSEENKTLFLNKGSDGSGSKGWVVKLKEGQRVTVKPTVVLR
TAFVTIRKYKDDGCGADTAILGINTADGGALTPRSARPIVPEANKDVAQYSGHKTTSKGKSIPIGCMEKGGKTVCPNGYV
YDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3123 bp        

>NTDB_id=1143949 C7S05_RS00310 WP_144996877.1 52273..55395(-) (pilC) [Neisseria gonorrhoeae strain WHO F]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGCGCAGGCGCAAACCCGTAAATACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGAGGGTC
AATATAGTCAATCAACATTAAAGGACAAAGGCAGGGAGCGGACATTTAGCCATACGAGCCAGAGAAACTGGAACGGCCAA
CAAAACAATTTTATCTCATTCAACAATAGCGATGAGCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCAC
CTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATGCCGACGGGCTGAAAAAGCGCGGCAATGCCGTGAATTGGATTC
GTACCACCCGGCCCGGGCTGGCAGGCTACATCTACACCGGCGTCATATGCAGAGACACAGGGCAATGCCCCGAACTTGTC
TATGAGACCAAATTTTCCTTCGACGGCATCGATTTGGCAAAAGGGGGAAACCGAAAGCTGGATAGGCACCCGGACCCAAG
CCGCGAAAATTTGCCCATTTACAAATTGAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCGGCGAGGGTACCG
CCAAAGATGGCAGATCATCCAGCAGATGGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTTTACGACA
CGAGGCCACCCTATTTCCCTTGGCGACTGGCAGCGCGAAAGTACCGCCATGGCCTATTATCTGGACGCCAAACTGCACCT
GCTGGATAAAACACAGATTGAAAATATCGCGCCAGGCAAAACAGTGAATTTGGGCATCTTGAGACCGCGCGTCGAGGCAA
AGGTAAGGCGGAAGTGGGATCTGCTAAATTTTTGGGCTAAGTGGGACATTAAAGATACCGGGCAGATTCCGGTCAAGCTC
GGCCTGCCGGAAGTCAAAGCAGGCCGCTGCATCAACAAACCGAACCCCAATCCCAAATCAGCCCTTTCGCCGGCACTGAC
CGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGGCA
GCTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTAAAACCGACCCCGCCCGGCCCGGCCGGCATTCCCTCGCCGCT
TTGAATGCGCAGGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCCGATTGCCGGGCGGCGTGTA
CCAGATCGCCCCGGGCAATAGCGGCCGGGTCGCGGGTTTTAATGGCAATGACGGCAAAAACGACACTTTCGGCATCTACA
AGGACAGGCTCGTCACACCTGAGGCCGACGAGTGGAGCGAAGTGCTGCTGCCTTGGACGGCTCGGTATTACGGTAATGAC
GATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACAGCCAAAAATACCGCATCCG
CACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGCGGTCGGCGGGTATC
TGGCAACTTCTGCCAACGACGGGATGGTGCATATCTTCAAAAAAACCGGCACAGACCAACGAGGCTACGAACTGAAGCTC
AGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAAACCAAGACTCCACCCTCGCCAAAGAGCTGCGCACCTTTGC
CGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCAGCATTACAGATGACCAAGACAGGC
AAAAACATTTCTTTATGTTCGGCGCAATGGGCCTTGGCGGCAGAGGCGCATACGCCTTGGATTTAAGCAAAATCGACAGC
AACCCGGTCGGCGTTTCCATGTTTGATGTCCAAAACGAGAGTAAAAATAATGGCGTGAAATTAGGCTACACCGTCGGCAC
GCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGGCTAAACAAATTGCCAGCC
AAGAAAATAAAACCGCGCTGTATGTGTATGATTTGAAAGACACCTTAGGTACGCCGATTGCAAAAATCGAAGCACCCGGC
GGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTCGATATCGCCTATGCCGGCGACCG
GGGCGGCAATATGTACCGCTTTGATTTGAGCAATTCCGATTCTAGTAAATGGTCTGCAAAGGTTATTTTCGAAGGCGACA
AGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTCGTCATCTTCGGTACGGGCAGCGATTTGAGT
GAAGAAGATGTACTGAATGCGGACGAACAATATATTTACGGTATCTTTGACGACGATAAGGGGACGGTTAATGTAAAGGT
AACAAACGGCACGGGAGGCGGGCTGCTCGAGCAAGTGCTTAGCGAGGAAAATAAAACATTATTCCTGAACAAGGGATCCG
ACGGATCGGGCAGTAAGGGGTGGGTAGTGAAGCTGAAGGAAGGACAACGCGTTACCGTCAAACCGACCGTGGTATTGCGT
ACCGCCTTCGTAACCATCCGCAAGTATAAAGACGACGGCTGCGGCGCGGATACCGCCATTTTGGGCATCAATACCGCCGA
CGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGAAGCCAATAAGGATGTCGCACAATATTCCGGCCATA
AGACAACCTCCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGGCGGTAAAACCGTCTGCCCGAACGGATATGTT
TACGACAAGCCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGG
CGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGC
TGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTC
TGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(519-849)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

72.529

100

0.734

Multiple sequence alignment