Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   A8Q77_RS02020 Genome accession   NZ_LT571436
Coordinates   444295..446535 (+) Length   746 a.a.
NCBI ID   WP_064130325.1    Uniprot ID   -
Organism   Neisseria weaveri strain NCTC13585     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 439295..451535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A8Q77_RS01995 (SAMEA3174300_00396) ppx 439794..441302 (-) 1509 WP_004283568.1 exopolyphosphatase -
  A8Q77_RS02000 (SAMEA3174300_00397) - 441542..441958 (+) 417 WP_004283566.1 NfeD family protein -
  A8Q77_RS02005 (SAMEA3174300_00398) - 441986..442942 (+) 957 WP_107726493.1 SPFH domain-containing protein -
  A8Q77_RS02010 (SAMEA3174300_00399) rlmB 443373..444122 (-) 750 WP_004283560.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  A8Q77_RS02020 (SAMEA3174300_00400) comA 444295..446535 (+) 2241 WP_064130325.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A8Q77_RS02025 (SAMEA3174300_00401) rep 446600..448609 (-) 2010 WP_064130326.1 DNA helicase Rep -
  A8Q77_RS02030 (SAMEA3174300_00402) - 448825..449184 (+) 360 WP_004283554.1 hypothetical protein -
  A8Q77_RS02035 (SAMEA3174300_00403) - 449188..449610 (+) 423 WP_004283553.1 protein YgfX -
  A8Q77_RS02040 (SAMEA3174300_00404) folC 449955..451247 (+) 1293 WP_064130327.1 bifunctional tetrahydrofolate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 81020.90 Da        Isoelectric Point: 9.4541

>NTDB_id=1143788 A8Q77_RS02020 WP_064130325.1 444295..446535(+) (comA) [Neisseria weaveri strain NCTC13585]
MALRFGLPFWIFGVLLSFALPVVPPLWVWTAVGCCAAVLFRRYRSLALLLLCLTAGAAYGVWRTEAALSQQWQTASAADL
TVTVDDLPQREARRVRFTAVAEDEAGRQYRLVLSDYGLRDWPVGSRWQVRARVRPPVGEVNPAGFNREAWALAKGIDGLG
TIGGERVLLAQGEAGRLLRMRDSVSRRWQQAAVVKPEFSDGQALMRALGIGEQTALDTGVWQAFRPLGLNHLVSISGLHV
GMVALFAGWLAKLLLACLPFSLSKPRLWMVSAGVAAGIFYAGLAGFSVPTQRSVLMLAALAWAWWCGSGVSVWRGWWQAL
AAVLLVQPAAVLGAGFWLSFGLVAALLWVASGRLNGLGWRAVLRGQWAVSVLSVVILGAFFASVPLISPLVNAAAIPWFS
WVLTPLALLGSILPWPRLHEFAAAAGEYTLRFLLWLAEYAPEYAVAEVPWPLVLLAVVAGGVLLLPKPTALRPWAALVLC
GFVVYRKEPVQYGRVQMVVWDAGQGLSVLFQTAQHRLLFDTGTAPSAAMNILPALNAWGVRSLDTLVLSHHDADHDGGFE
AVARATRPKRLWAGQPQFYSGAESCDKGAWEWDGVHFEWLRPSEIVKADDNEQSCVLRVVAGGQAALVTGDLGKAGEKSL
VEQYGGGLHSNVLVLGHHGSDTSSSGVFLNAVAPEYAVASSGYANAYRHPVKAVRDRVQAHDIVLLRTDWQGALRFELGA
GGEVFGGPLRQRKPYWQKKPFDNAPY

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=1143788 A8Q77_RS02020 WP_064130325.1 444295..446535(+) (comA) [Neisseria weaveri strain NCTC13585]
ATGGCTTTGAGATTCGGTTTGCCGTTTTGGATTTTCGGCGTGTTACTGTCGTTTGCGTTGCCTGTCGTGCCGCCGTTGTG
GGTCTGGACGGCGGTCGGTTGCTGCGCGGCCGTATTGTTTCGGCGTTACCGCAGTTTGGCTTTATTGCTGTTGTGTTTGA
CGGCTGGAGCGGCTTACGGTGTGTGGCGGACGGAAGCGGCGTTGTCGCAGCAATGGCAGACGGCTTCTGCGGCGGATTTA
ACCGTTACGGTGGACGATTTGCCGCAACGTGAAGCACGGCGTGTGCGTTTTACGGCCGTGGCGGAGGACGAAGCGGGCAG
GCAGTACCGTTTGGTTTTGTCGGATTACGGTTTGCGCGATTGGCCGGTCGGCAGCCGCTGGCAGGTTCGCGCCCGCGTCC
GGCCGCCGGTCGGGGAAGTGAATCCGGCCGGTTTTAACCGTGAAGCGTGGGCTTTGGCGAAGGGTATAGACGGCTTGGGT
ACGATTGGCGGCGAACGTGTTTTGTTGGCGCAGGGCGAGGCCGGTCGGTTGCTGAGGATGCGCGATTCGGTCAGCAGGCG
TTGGCAGCAGGCGGCGGTGGTCAAGCCTGAATTTTCAGACGGCCAAGCGCTGATGCGGGCGTTGGGTATCGGCGAGCAGA
CGGCTTTGGATACGGGTGTGTGGCAGGCGTTCCGGCCTTTGGGTTTGAACCATTTGGTCAGTATTTCGGGATTGCATGTG
GGTATGGTGGCGTTGTTTGCCGGTTGGCTGGCAAAGTTGCTGCTGGCGTGTTTGCCGTTTTCGCTGTCGAAGCCGCGTTT
GTGGATGGTATCGGCAGGTGTGGCGGCCGGAATATTTTATGCCGGATTGGCCGGGTTTTCCGTGCCGACGCAGCGCAGTG
TATTGATGTTGGCGGCGTTGGCTTGGGCTTGGTGGTGCGGCAGCGGCGTATCGGTTTGGCGCGGTTGGTGGCAGGCGTTG
GCGGCCGTGCTGCTGGTTCAGCCTGCTGCGGTGTTGGGGGCGGGATTTTGGTTGTCGTTCGGTTTGGTGGCGGCACTGTT
GTGGGTTGCGTCAGGCCGTCTGAACGGTTTGGGTTGGCGTGCCGTATTAAGGGGACAATGGGCGGTATCGGTGTTGTCGG
TGGTGATATTGGGGGCATTTTTTGCTTCGGTGCCGCTGATCAGTCCTTTGGTGAATGCGGCGGCGATTCCGTGGTTTTCT
TGGGTGTTGACGCCGTTGGCCTTGCTCGGCTCTATATTGCCTTGGCCCCGGTTGCATGAATTTGCGGCGGCGGCAGGGGA
ATACACGCTGCGGTTTTTGTTGTGGCTGGCGGAGTATGCGCCCGAATATGCGGTGGCGGAGGTGCCGTGGCCGTTGGTAT
TGCTGGCGGTGGTAGCCGGAGGTGTGCTGTTGCTGCCGAAGCCGACGGCGTTGCGGCCTTGGGCGGCGTTGGTGTTGTGC
GGTTTTGTCGTGTATCGGAAAGAGCCTGTGCAATACGGGCGTGTGCAGATGGTGGTGTGGGACGCCGGGCAGGGTTTGTC
GGTGTTGTTTCAGACGGCGCAACATCGCTTGTTGTTTGATACGGGGACGGCGCCGTCGGCCGCCATGAATATTTTGCCTG
CGCTGAATGCTTGGGGCGTCCGCAGTTTGGATACGCTGGTGTTGTCCCATCACGATGCCGACCATGACGGCGGTTTTGAA
GCGGTTGCCCGTGCCACGCGGCCGAAACGCTTGTGGGCGGGGCAGCCGCAGTTTTATTCGGGCGCGGAAAGTTGTGATAA
AGGAGCTTGGGAATGGGACGGGGTGCATTTCGAATGGTTGAGGCCGTCTGAAATTGTTAAGGCGGACGATAACGAGCAAA
GCTGTGTATTAAGGGTGGTTGCCGGCGGACAGGCGGCTTTGGTCACGGGGGATTTGGGCAAGGCAGGGGAGAAAAGTCTG
GTGGAACAATACGGCGGGGGTTTGCACAGCAATGTTTTGGTTTTGGGGCATCACGGCAGCGATACGTCGTCTTCCGGCGT
GTTTTTAAATGCGGTGGCGCCTGAATATGCGGTGGCTTCGAGCGGTTATGCCAATGCTTACCGCCATCCGGTCAAAGCCG
TGCGCGACCGTGTGCAGGCGCATGATATTGTGTTGCTGCGTACGGATTGGCAGGGCGCGTTGCGGTTTGAATTGGGCGCG
GGCGGCGAGGTGTTTGGCGGACCTTTGCGGCAGCGCAAACCTTATTGGCAGAAAAAGCCTTTTGATAATGCTCCGTATTG
A

Domains

Predicted by InterProScan.

Domain of unknown function (DUF4131) (DUF4131)

(25-164)

Metallo-beta-lactamase superfamily (Lactamase_B)

(501-649)

Competence protein (Competence)

(209-464)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

61.156

99.732

0.61

Multiple sequence alignment