Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   MESINF_RS08940 Genome accession   NZ_LS974202
Coordinates   1976735..1977646 (+) Length   303 a.a.
NCBI ID   WP_169700983.1    Uniprot ID   A0A7Z7PS08
Organism   Mesotoga infera isolate MESINF1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1971735..1982646
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MESINF_RS08920 (MESINF_1893) - 1971912..1973758 (-) 1847 Protein_1766 ABC transporter substrate-binding protein -
  MESINF_RS08930 (MESINF_1896) - 1974018..1974866 (-) 849 WP_169699496.1 purine-nucleoside phosphorylase -
  MESINF_RS08935 (MESINF_1897) - 1974987..1976735 (+) 1749 WP_169699497.1 proline--tRNA ligase -
  MESINF_RS08940 (MESINF_1898) pilA 1976735..1977646 (+) 912 WP_169700983.1 signal recognition particle-docking protein FtsY Machinery gene
  MESINF_RS08945 (MESINF_1899) - 1977650..1978111 (+) 462 WP_169699498.1 Rrf2 family transcriptional regulator -
  MESINF_RS08950 (MESINF_1900) coaD 1978175..1978651 (+) 477 WP_169700985.1 pantetheine-phosphate adenylyltransferase -
  MESINF_RS08955 (MESINF_1901) tsf 1978731..1979336 (+) 606 WP_169699499.1 translation elongation factor Ts -
  MESINF_RS08960 (MESINF_1902) pyrH 1979386..1980087 (+) 702 WP_169699500.1 UMP kinase -
  MESINF_RS08965 (MESINF_1903) eno 1980101..1981384 (+) 1284 WP_169699501.1 phosphopyruvate hydratase -
  MESINF_RS08970 (MESINF_1904) sdaAB 1981445..1982110 (+) 666 WP_169699502.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 32890.74 Da        Isoelectric Point: 6.3668

>NTDB_id=1143003 MESINF_RS08940 WP_169700983.1 1976735..1977646(+) (pilA) [Mesotoga infera isolate MESINF1]
MGIFSRIKEGLKKTRDGFFKNVKKLLSFDRLDENTLEEIEELLILSDMGSETSQEVISALRERTHKGRNPTEVLKDVLTE
ILDIPYEQKTGKPYVISVVGVNGTGKTTTIGKLSGLYSQQGKRVVLAACDTFRAAAVEQLRVWSDRSGVDFISQGQGADS
AAVAFDAINHAVSKGKDVVIIDTAGRLHTKSNLMEELKKVHRVIGKAVQGAPHEVLLVIDATTGQNGLIQAAKFKEAVNV
TGIVLTKLDGTAKGGIIFAIVKELGIPVKYIGVGEKIDDLKPFKPSEFVEALLSNDEESSEEV

Nucleotide


Download         Length: 912 bp        

>NTDB_id=1143003 MESINF_RS08940 WP_169700983.1 1976735..1977646(+) (pilA) [Mesotoga infera isolate MESINF1]
ATGGGAATCTTTTCCAGAATAAAGGAAGGGCTGAAAAAGACCCGAGACGGTTTCTTCAAAAACGTCAAAAAACTTCTTTC
CTTCGACAGGCTAGACGAGAATACGCTCGAAGAGATCGAGGAGTTGCTGATACTCTCCGATATGGGCTCTGAGACTTCTC
AAGAGGTAATATCGGCCCTGAGAGAGAGAACGCATAAAGGCAGAAATCCGACGGAAGTCCTAAAAGACGTGCTTACGGAG
ATTCTCGATATCCCTTACGAGCAGAAAACCGGGAAGCCTTATGTCATATCGGTTGTGGGCGTGAACGGAACGGGAAAGAC
CACCACGATTGGAAAACTGTCGGGACTCTATTCTCAACAGGGAAAGAGAGTTGTGCTAGCGGCCTGCGATACTTTCAGAG
CCGCGGCGGTTGAGCAACTTCGAGTATGGAGCGACAGATCGGGAGTAGATTTCATAAGCCAGGGTCAGGGCGCTGACTCC
GCGGCAGTCGCTTTCGACGCTATAAACCACGCAGTAAGCAAAGGGAAAGACGTTGTTATAATTGATACGGCCGGGAGACT
TCATACCAAAAGCAACCTGATGGAAGAGTTGAAGAAGGTCCACAGGGTTATCGGGAAAGCGGTTCAGGGAGCTCCACACG
AAGTTCTACTTGTAATAGACGCTACGACGGGTCAAAACGGTCTTATTCAAGCAGCTAAGTTCAAGGAAGCGGTGAATGTC
ACGGGTATAGTACTCACGAAACTGGACGGAACGGCAAAGGGTGGCATAATATTTGCCATCGTGAAGGAACTGGGAATACC
GGTTAAATATATAGGTGTTGGCGAGAAGATAGACGATCTCAAGCCCTTCAAGCCGTCAGAGTTCGTGGAAGCTCTCCTTT
CAAACGATGAGGAGAGTTCTGAGGAGGTATAG

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(94-293)

SRP54-type protein, helical bundle domain (SRP54_N)

(19-81)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7Z7PS08

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

48.344

99.67

0.482

Multiple sequence alignment