Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DQL00_RS04270 Genome accession   NZ_LS483523
Coordinates   789995..790819 (+) Length   274 a.a.
NCBI ID   WP_023396715.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836169     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 784995..795819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL00_RS04235 asnA 785085..786077 (+) 993 WP_000747993.1 aspartate--ammonia ligase -
  DQL00_RS04240 rsmD 786142..786681 (+) 540 WP_000691938.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  DQL00_RS04245 coaD 786671..787159 (+) 489 WP_001280746.1 pantetheine-phosphate adenylyltransferase -
  DQL00_RS04250 sepM 787143..788180 (+) 1038 WP_000727277.1 SepM family pheromone-processing serine protease Regulator
  DQL00_RS04255 - 788238..788468 (+) 231 WP_000250391.1 DUF1146 family protein -
  DQL00_RS04260 murA 788492..789775 (+) 1284 WP_023396463.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DQL00_RS04265 - 789768..789956 (+) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  DQL00_RS04270 endA 789995..790819 (+) 825 WP_023396715.1 DNA-entry nuclease EndA Machinery gene
  DQL00_RS04275 - 791110..792441 (+) 1332 WP_000390042.1 hemolysin family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29935.62 Da        Isoelectric Point: 10.1197

>NTDB_id=1142952 DQL00_RS04270 WP_023396715.1 789995..790819(+) (endA) [Streptococcus pneumoniae strain 4041STDY6836169]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQAPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1142952 DQL00_RS04270 WP_023396715.1 789995..790819(+) (endA) [Streptococcus pneumoniae strain 4041STDY6836169]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCAGTCGACAGCTAATAGTCCTAAAACCAAGCTTAGTCAGAAAAAACAAGCGCCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAATGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

97.81

100

0.978
  endA Streptococcus pneumoniae D39

97.81

100

0.978
  endA Streptococcus pneumoniae R6

97.81

100

0.978
  endA Streptococcus pneumoniae TIGR4

97.81

100

0.978

Multiple sequence alignment