Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | DQL26_RS01200 | Genome accession | NZ_LS483521 |
| Coordinates | 209840..211201 (+) | Length | 453 a.a. |
| NCBI ID | WP_111693002.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain NCTC8316 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 174260..209759 | 209840..211201 | flank | 81 |
Gene organization within MGE regions
Location: 174260..211201
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DQL26_RS01030 (NCTC8316_00201) | - | 174260..175456 (+) | 1197 | WP_002986345.1 | quaternary amine ABC transporter ATP-binding protein | - |
| DQL26_RS01035 (NCTC8316_00202) | - | 175472..177199 (+) | 1728 | WP_111692994.1 | ABC transporter permease/substrate binding protein | - |
| DQL26_RS01040 (NCTC8316_00203) | polA | 177330..179972 (+) | 2643 | WP_111692995.1 | DNA polymerase I | - |
| DQL26_RS01045 (NCTC8316_00204) | - | 180159..180614 (+) | 456 | WP_002986334.1 | CoA-binding protein | - |
| DQL26_RS01050 (NCTC8316_00205) | perR | 180666..181133 (+) | 468 | WP_002986328.1 | peroxide-responsive transcriptional repressor PerR | - |
| DQL26_RS01055 | - | 181353..181589 (+) | 237 | WP_015055907.1 | hypothetical protein | - |
| DQL26_RS01060 (NCTC8316_00207) | - | 181811..183145 (+) | 1335 | WP_111692996.1 | phosphoadenosine phosphosulfate reductase | - |
| DQL26_RS01065 (NCTC8316_00208) | - | 183138..183668 (+) | 531 | WP_002987925.1 | IbrB-like domain-containing protein | - |
| DQL26_RS08865 | - | 183715..183864 (-) | 150 | Protein_158 | ISL3 family transposase | - |
| DQL26_RS01075 | - | 183996..185146 (-) | 1151 | Protein_159 | IS3 family transposase | - |
| DQL26_RS01085 (NCTC8316_00213) | - | 185224..186534 (-) | 1311 | WP_111692997.1 | SLC13 family permease | - |
| DQL26_RS01090 (NCTC8316_00214) | nadC | 186758..187630 (+) | 873 | WP_010921848.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| DQL26_RS01100 (NCTC8316_00217) | - | 189358..190221 (-) | 864 | WP_011888568.1 | DUF975 family protein | - |
| DQL26_RS09130 | - | 190258..190443 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| DQL26_RS01110 (NCTC8316_00218) | tgt | 190440..191582 (+) | 1143 | WP_011528208.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| DQL26_RS01115 (NCTC8316_00219) | - | 191799..192140 (+) | 342 | WP_111692998.1 | CHY zinc finger protein | - |
| DQL26_RS01120 (NCTC8316_00220) | - | 192115..192654 (+) | 540 | WP_014407272.1 | biotin transporter BioY | - |
| DQL26_RS01125 (NCTC8316_00221) | - | 192794..193573 (+) | 780 | WP_111692999.1 | MBL fold metallo-hydrolase | - |
| DQL26_RS01130 (NCTC8316_00222) | tadA | 193573..194088 (+) | 516 | WP_030126469.1 | tRNA adenosine(34) deaminase TadA | - |
| DQL26_RS01135 (NCTC8316_00223) | - | 194702..195934 (-) | 1233 | WP_009880892.1 | transglutaminase domain-containing protein | - |
| DQL26_RS01145 (NCTC8316_00225) | speG | 196334..197038 (+) | 705 | WP_111693000.1 | streptococcal pyrogenic exotoxin SpeG | - |
| DQL26_RS01150 (NCTC8316_00227) | - | 197493..198842 (+) | 1350 | WP_014635263.1 | glucose-6-phosphate isomerase | - |
| DQL26_RS01155 | - | 199189..200697 (-) | 1509 | WP_023079312.1 | helix-turn-helix domain-containing protein | - |
| DQL26_RS01160 (NCTC8316_00230) | - | 201385..202056 (+) | 672 | WP_111693001.1 | rhomboid family intramembrane serine protease | - |
| DQL26_RS01165 (NCTC8316_00231) | galU | 202155..203054 (-) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| DQL26_RS01170 (NCTC8316_00232) | - | 203087..204103 (-) | 1017 | WP_111685652.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| DQL26_RS01175 | - | 204401..204832 (+) | 432 | Protein_177 | MarR family transcriptional regulator | - |
| DQL26_RS01180 (NCTC8316_00234) | - | 204825..206531 (+) | 1707 | WP_010921864.1 | ABC transporter ATP-binding protein | - |
| DQL26_RS01185 (NCTC8316_00235) | - | 206534..208318 (+) | 1785 | WP_002992923.1 | ABC transporter ATP-binding protein | - |
| DQL26_RS01190 (NCTC8316_00236) | - | 208436..209203 (+) | 768 | WP_002986113.1 | epoxyqueuosine reductase QueH | - |
| DQL26_RS01195 (NCTC8316_00237) | - | 209313..209759 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| DQL26_RS01200 (NCTC8316_00238) | radA | 209840..211201 (+) | 1362 | WP_111693002.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49382.69 Da Isoelectric Point: 6.0962
>NTDB_id=1142818 DQL26_RS01200 WP_111693002.1 209840..211201(+) (radA) [Streptococcus pyogenes strain NCTC8316]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGPVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGPVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=1142818 DQL26_RS01200 WP_111693002.1 209840..211201(+) (radA) [Streptococcus pyogenes strain NCTC8316]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGACCGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATCGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGACCGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATCGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae D39 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae R6 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae Rx1 |
85.43 |
100 |
0.854 |
| radA | Streptococcus mitis SK321 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae TIGR4 |
85.43 |
100 |
0.854 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |