Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   DQL14_RS05295 Genome accession   NZ_LS483488
Coordinates   1051630..1053414 (+) Length   594 a.a.
NCBI ID   WP_108168998.1    Uniprot ID   -
Organism   Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1046630..1058414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL14_RS05265 (NCTC11637_01042) motB 1047402..1048169 (+) 768 WP_108168995.1 flagellar motor protein MotB -
  DQL14_RS05270 (NCTC11637_01043) - 1048175..1048612 (+) 438 WP_001883762.1 hypothetical protein -
  DQL14_RS05275 (NCTC11637_01044) - 1048681..1050342 (+) 1662 WP_108168996.1 ABC transporter permease/substrate-binding protein -
  DQL14_RS05280 (NCTC11637_01045) - 1050344..1050985 (+) 642 WP_108168997.1 ATP-binding cassette domain-containing protein -
  DQL14_RS05285 - 1050997..1051176 (-) 180 WP_001912514.1 hypothetical protein -
  DQL14_RS05290 (NCTC11637_01046) - 1051168..1051629 (+) 462 WP_000437179.1 hypothetical protein -
  DQL14_RS05295 (NCTC11637_01047) uvrC 1051630..1053414 (+) 1785 WP_108168998.1 excinuclease ABC subunit UvrC Machinery gene
  DQL14_RS05300 (NCTC11637_01048) - 1053425..1054690 (+) 1266 WP_108168999.1 homoserine dehydrogenase -
  DQL14_RS05305 (NCTC11637_01049) - 1054691..1055035 (+) 345 WP_001211718.1 YraN family protein -
  DQL14_RS05310 (NCTC11637_01050) trxA 1055124..1055444 (+) 321 WP_000020199.1 thioredoxin -
  DQL14_RS05315 (NCTC11637_01051) trxB 1055450..1056385 (+) 936 WP_108169000.1 thioredoxin-disulfide reductase -
  DQL14_RS05320 (NCTC11637_01052) - 1056593..1057414 (+) 822 WP_108169001.1 glycosyltransferase family 25 protein -
  DQL14_RS05325 (NCTC11637_01053) - 1057633..1057881 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68551.70 Da        Isoelectric Point: 9.5288

>NTDB_id=1142665 DQL14_RS05295 WP_108168998.1 1051630..1053414(+) (uvrC) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYSKIAKECLEMIENKDKLIKELELKMECLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSTFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRGQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKHLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGNFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=1142665 DQL14_RS05295 WP_108168998.1 1051630..1053414(+) (uvrC) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAACAGCAGCGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ACCATCGCGCCAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAATGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTGA
AAATGGAGTGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCCCTCATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGTGCAAGCAATAAAGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAACGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAGCGCTTAAAGAATTGCAAGAATTTATCTCCCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAGTGCATGCCTTATAGGGTGGAAATTTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCCTTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAATGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTATGGGTGATCGATGGAGGGAGGGGGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAACACTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGTGTGAAAAAATTATTGGATTATTTTGGGAATTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968

Multiple sequence alignment