Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   DQL14_RS01185 Genome accession   NZ_LS483488
Coordinates   244996..245733 (+) Length   245 a.a.
NCBI ID   WP_000660523.1    Uniprot ID   A0AAD1D9W4
Organism   Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 239996..250733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL14_RS01160 (NCTC11637_00234) panD 242154..242507 (+) 354 WP_000142226.1 aspartate 1-decarboxylase -
  DQL14_RS01165 (NCTC11637_00235) - 242510..242812 (+) 303 WP_000347928.1 YbaB/EbfC family nucleoid-associated protein -
  DQL14_RS01170 (NCTC11637_00236) - 242812..243807 (+) 996 WP_108169555.1 PDZ domain-containing protein -
  DQL14_RS01175 (NCTC11637_00237) comB6 243815..244870 (+) 1056 WP_108169556.1 P-type conjugative transfer protein TrbL Machinery gene
  DQL14_RS01180 (NCTC11637_00238) comB7 244886..244999 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  DQL14_RS01185 (NCTC11637_00239) comB8 244996..245733 (+) 738 WP_000660523.1 type IV secretion system protein Machinery gene
  DQL14_RS01190 (NCTC11637_00240) comB9 245733..246713 (+) 981 WP_108169557.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  DQL14_RS01195 (NCTC11637_00241) comB10 246706..247842 (+) 1137 WP_108169558.1 DNA type IV secretion system protein ComB10 Machinery gene
  DQL14_RS01200 (NCTC11637_00242) - 247913..249325 (+) 1413 WP_108169559.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  DQL14_RS01205 (NCTC11637_00243) gmd 249367..250512 (+) 1146 WP_111735917.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28530.74 Da        Isoelectric Point: 8.9546

>NTDB_id=1142658 DQL14_RS01185 WP_000660523.1 244996..245733(+) (comB8) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1142658 DQL14_RS01185 WP_000660523.1 244996..245733(+) (comB8) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAATTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGTTGGAGAGAAACCGATTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCTATTGCGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTATTGAGCTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACCCGCTACAGCATCACTGAAATC
ACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.976

Multiple sequence alignment