Detailed information NTG1142655

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: DQL14_RS01065
• Genome accession: NZ_LS483488
• Coordinates: 221686..224049 (+)
• Length: 787 a.a.
• NCBI ID: WP_108169543.1
• Uniprot ID: -
• Organism: Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 216686..229049

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL14_RS01030 (NCTC11637_00212)	groES	216715..217071 (-)	357	WP_000671927.1	co-chaperone GroES	-
DQL14_RS01040 (NCTC11637_00213)	dnaG	217349..219028 (+)	1680	WP_108169539.1	DNA primase	-
DQL14_RS01045 (NCTC11637_00214)	-	219025..220077 (+)	1053	WP_108169540.1	MnmA/TRMU family protein	-
DQL14_RS01050 (NCTC11637_00215)	-	220167..220994 (+)	828	WP_108169541.1	DUF5718 family protein	-
DQL14_RS01055 (NCTC11637_00216)	comB2	221140..221421 (+)	282	WP_001272690.1	TrbC/VirB2 family protein	Machinery gene
DQL14_RS01060 (NCTC11637_00217)	comB3	221421..221684 (+)	264	WP_108169542.1	competence protein ComB	Machinery gene
DQL14_RS01065 (NCTC11637_00218)	comB4	221686..224049 (+)	2364	WP_108169543.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
DQL14_RS01075 (NCTC11637_00220)	-	224368..225708 (+)	1341	WP_162296840.1	COG3014 family protein	-
DQL14_RS01080 (NCTC11637_00221)	cheV1	225809..226774 (+)	966	WP_000785454.1	chemotaxis protein CheV1	-
DQL14_RS01085 (NCTC11637_00222)	nspC	226771..227988 (+)	1218	WP_108169545.1	carboxynorspermidine decarboxylase	-
DQL14_RS01090 (NCTC11637_00223)	lpxE	227998..228531 (-)	534	WP_231952923.1	lipid A 1-phosphatase LpxE	-

Sequence

Protein

• Length: 787 a.a.
• Molecular weight: 90313.94 Da
• Isoelectric Point: 8.8662

>NTDB_id=1142655 DQL14_RS01065 WP_108169543.1 221686..224049(+) (comB4) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
MLEKLLSAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEYFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQNIQTDSKYLQAILNQFENKEVYENQYFLVLESAHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSVNKTLGFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLVLGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGKSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAIFSAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGNSNMIDVSLESLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide

• Length: 2364 bp

>NTDB_id=1142655 DQL14_RS01065 WP_108169543.1 221686..224049(+) (comB4) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
ATGTTAGAAAAGCTTTTGAGCGCTATCAAACAAAAGGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGTATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTCTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTTGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAACATTCAAACTGACTCTAA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAACAAAGAGGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCGCGC
ATTCTTTACAGGGCGTTTTAGAGCATAAGAAAAAATCCTTAATGCATGCCAATAGGGAAAATTTTAAGGACATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAGCTC
CAAAGAGGTTTTGAATTTTTATGCGGAATACATTAACGGGTTTGATCTCCCCTTAAAGCCCCTAGTAGGGGGGTATTTGA
GCGATAGTTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAGCGCATCACTTCTATAGCGATCGGAGCGCTTTTATACCAAGAGACGCC
ACTAGATATTATCTTTTCTATAGAGCCTATGAGCGTCAATAAAACGCTGGGTTTTTTAAAAGAGAGGGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAGTTTTAGGGCTTTTATTTAAAGA
AAATTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCACTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCTTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAATCATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGACAGGATGCAGGGGCTG
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCAAATCTTTTAGCATCAACCCCTTTTGTTTAGAACCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTCTTTTTGAGCATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTGG
AAGATATGAATGCGATTTTTAGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGCTTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACTTCGTCTAACCAATTGGGCTTGAGTTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAATGTGATAAACCTAGACACCATCACCCAAAACCCCAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTGCTGAACACCAAAATTAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGATATTTACCAATTAAGTGGGGTTAAAAACGCTCATAGTTTTTTGAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAGCACCATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCCTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAATGGGAATTCTAACATGATTGATGT
GAGTTTAGAAAGTTTAGGGCGTTATTTGAAAATCTTTAATTCAGACTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (426-466)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (176-375)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	98.094	100	0.981