Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DQL46_RS04750 Genome accession   NZ_LS483482
Coordinates   1021227..1021943 (-) Length   238 a.a.
NCBI ID   WP_002461418.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain NCTC12217     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1016227..1026943
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL46_RS04730 (NCTC12217_00964) - 1016282..1017526 (+) 1245 WP_070648266.1 ammonium transporter -
  DQL46_RS04735 (NCTC12217_00965) - 1017626..1018576 (+) 951 WP_002461422.1 LacI family DNA-binding transcriptional regulator -
  DQL46_RS04740 (NCTC12217_00966) - 1018676..1020160 (+) 1485 WP_070648267.1 sucrose-6-phosphate hydrolase -
  DQL46_RS04745 (NCTC12217_00967) - 1020161..1021135 (+) 975 WP_070544733.1 carbohydrate kinase family protein -
  DQL46_RS04750 (NCTC12217_00968) agrA 1021227..1021943 (-) 717 WP_002461418.1 quorum-sensing response regulator AgrA Regulator
  DQL46_RS04755 (NCTC12217_00969) agrC 1021956..1023245 (-) 1290 WP_070648269.1 quorum-sensing sensor histidine kinase AgrC -
  DQL46_RS04760 (NCTC12217_00970) agrD 1023267..1023410 (-) 144 WP_002477921.1 cyclic lactone autoinducer peptide AgrD -
  DQL46_RS04765 (NCTC12217_00971) - 1023413..1023979 (-) 567 WP_176744568.1 accessory gene regulator AgrB -
  DQL46_RS04770 (NCTC12217_00973) - 1024607..1025392 (-) 786 WP_002477923.1 carbon-nitrogen family hydrolase -
  DQL46_RS04775 (NCTC12217_00974) - 1025527..1026150 (-) 624 WP_062077860.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27935.92 Da        Isoelectric Point: 5.9140

>NTDB_id=1142509 DQL46_RS04750 WP_002461418.1 1021227..1021943(-) (agrA) [Staphylococcus lugdunensis strain NCTC12217]
MKIYICEDDVKQRENMVEIINNYIMIEEKPMEIALATDNPYEILKMSKENEDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPAELKTRIIDCLETAHTRLKLLSKERTVETIELKRGSNSVYVQYDEVM
FFESSTNSHRLIAHLDNRQIEFYGNLKQISQIDDRFFRCHNSFVVNRHNISSINSKERVVYFKNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1142509 DQL46_RS04750 WP_002461418.1 1021227..1021943(-) (agrA) [Staphylococcus lugdunensis strain NCTC12217]
ATGAAGATTTACATTTGTGAAGATGATGTTAAACAACGTGAAAATATGGTTGAGATCATCAATAACTATATCATGATTGA
AGAAAAACCAATGGAAATTGCTTTAGCTACAGATAATCCTTATGAAATTTTAAAAATGTCAAAGGAAAATGAGGATGTTG
GTTGTTATTTTTTAGATATTCAATTAGAAGCTGACATAAACGGTATCAAGTTAGGTAGCGAAATAAGAAAGTATGATCCG
ATAGGTAACATAATTTTTGTTACAAGTCATAGTGAGCTGACATATTTAACTTTTGTTTACAAAGTATCGGCTATGGATTT
TATTTTTAAAGATGACCCTGCCGAACTTAAAACTCGTATTATCGATTGCCTTGAAACCGCACATACGCGCTTAAAGTTAT
TGTCAAAAGAACGTACCGTTGAAACGATAGAGCTTAAGCGCGGTAGTAATTCTGTATATGTGCAATATGATGAAGTGATG
TTTTTTGAATCATCAACAAATTCACATCGATTGATTGCACATTTAGATAATCGTCAAATTGAGTTTTATGGTAATCTAAA
ACAAATTAGTCAAATCGATGATCGTTTCTTTAGATGCCATAATAGTTTTGTTGTCAATCGACACAATATCTCTTCAATCA
ATTCAAAAGAACGTGTTGTATATTTTAAAAATGGTGAACATTGTTATGCATCAGTACGCAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.555

100

0.866

Multiple sequence alignment