Detailed information NTG1142313

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DQN71_RS04015
• Genome accession: NZ_LS483471
• Coordinates: 778197..779045 (+)
• Length: 282 a.a.
• NCBI ID: WP_015604694.1
• Uniprot ID: A0A512AB23
• Organism: Streptococcus cristatus strain NCTC13807
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 773197..784045

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN71_RS03985 (NCTC13807_00766)	-	773369..774247 (+)	879	WP_015604689.1	F0F1 ATP synthase subunit gamma	-
DQN71_RS03990 (NCTC13807_00767)	atpD	774285..775691 (+)	1407	WP_005589740.1	F0F1 ATP synthase subunit beta	-
DQN71_RS03995 (NCTC13807_00768)	-	775699..776121 (+)	423	WP_095666415.1	F0F1 ATP synthase subunit epsilon	-
DQN71_RS04000 (NCTC13807_00769)	-	776363..776593 (+)	231	WP_041826785.1	DUF1146 family protein	-
DQN71_RS04005 (NCTC13807_00770)	murA	776662..777942 (+)	1281	WP_015604692.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQN71_RS04010 (NCTC13807_00771)	-	777935..778123 (+)	189	WP_015604693.1	DNA-directed RNA polymerase subunit beta	-
DQN71_RS04015 (NCTC13807_00772)	endA	778197..779045 (+)	849	WP_015604694.1	DNA/RNA non-specific endonuclease	Machinery gene
DQN71_RS04020 (NCTC13807_00773)	-	779253..780212 (+)	960	WP_015604695.1	ROK family glucokinase	-
DQN71_RS04025 (NCTC13807_00774)	-	780257..780664 (+)	408	WP_015604696.1	hypothetical protein	-
DQN71_RS04030 (NCTC13807_00775)	-	780748..781587 (+)	840	WP_015604697.1	thymidylate synthase	-
DQN71_RS04035 (NCTC13807_00776)	-	781723..782208 (+)	486	WP_015604698.1	hypothetical protein	-
DQN71_RS04040 (NCTC13807_00777)	-	782362..782874 (+)	513	WP_015604699.1	dihydrofolate reductase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 30590.18 Da
• Isoelectric Point: 10.0827

>NTDB_id=1142313 DQN71_RS04015 WP_015604694.1 778197..779045(+) (endA) [Streptococcus cristatus strain NCTC13807]
MPKRKKLQKKGTKSTQTVAGLLVALTLSLGAYFFGNANQSPSVNTPAVVSQNKDTSTPDQALAESVLTDSVRSQLGGKIE
WNRAGSFIINENQTNLDAKVSSVPYADNKTKMVQGQTVPTVANALLAKSTRQYKSREETGNGSTSWVPAGWHQVKHLSGE
YNHAVDRGHLLAYSLVGGLKGFDASTSNPANIAVQTAWANQANKDNSTGQNYYETQVRRALDQNKRVRYRVTLIYASEND
LVPSGSHLEAKSSDGSLEFNVFVPNVQSGIVLDYRTGKVTLI

Nucleotide

• Length: 849 bp

>NTDB_id=1142313 DQN71_RS04015 WP_015604694.1 778197..779045(+) (endA) [Streptococcus cristatus strain NCTC13807]
ATGCCAAAAAGAAAGAAATTACAAAAAAAGGGCACTAAATCTACTCAGACTGTAGCTGGTCTTCTGGTTGCTCTGACTTT
ATCACTGGGAGCCTACTTTTTTGGAAACGCCAATCAGTCACCATCAGTAAACACACCTGCAGTTGTCAGCCAAAATAAGG
ATACCAGTACACCAGATCAGGCATTGGCTGAGAGTGTTCTCACAGACTCAGTGCGTTCGCAACTTGGTGGAAAAATCGAG
TGGAATAGGGCTGGATCCTTCATTATCAATGAAAATCAAACAAACTTAGACGCTAAAGTTTCGAGTGTCCCTTATGCGGA
TAATAAAACGAAGATGGTTCAGGGACAGACGGTTCCAACAGTCGCCAATGCCTTGCTTGCCAAATCGACCCGCCAGTATA
AATCACGAGAAGAAACGGGAAATGGATCCACTTCTTGGGTTCCTGCCGGTTGGCACCAAGTCAAACATCTATCAGGTGAA
TACAACCATGCAGTAGATCGCGGGCATCTCTTGGCTTACTCTCTCGTCGGTGGCTTAAAGGGCTTTGATGCTTCCACTAG
CAATCCAGCCAATATCGCAGTCCAAACAGCCTGGGCCAATCAGGCCAATAAAGACAACTCGACGGGACAGAATTACTATG
AAACTCAAGTTCGTCGTGCTTTGGACCAGAATAAGCGAGTCCGCTATCGTGTCACTTTGATCTATGCTTCGGAAAATGAT
CTGGTGCCATCTGGCTCGCATTTAGAAGCCAAGTCCAGCGATGGAAGTTTGGAATTCAATGTCTTCGTTCCCAATGTCCA
GTCAGGAATTGTCCTTGATTATCGTACTGGCAAAGTGACCCTTATATAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (86-256)

3D structure

• AlphaFold DB: A0A512AB23

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	70.111	96.099	0.674
endA	Streptococcus pneumoniae D39	70.111	96.099	0.674
endA	Streptococcus pneumoniae R6	70.111	96.099	0.674
endA	Streptococcus pneumoniae TIGR4	70.111	96.099	0.674