Detailed information NTG1142202

Bioinformatically predicted

Overview

• Name: rec2
• Type: Machinery gene
• Locus tag: DQN30_RS05175
• Genome accession: NZ_LS483458
• Coordinates: 1022500..1024866 (+)
• Length: 788 a.a.
• NCBI ID: WP_111696536.1
• Uniprot ID: A0A2X4U305
• Organism: Haemophilus haemolyticus strain NCTC10839
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1017500..1029866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN30_RS05150 (NCTC10839_01025)	-	1017776..1019146 (-)	1371	WP_111696534.1	N-acetylmuramoyl-L-alanine amidase	-
DQN30_RS05155 (NCTC10839_01026)	tsaE	1019154..1019630 (-)	477	WP_005635434.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQN30_RS05160 (NCTC10839_01027)	folK	1019706..1020188 (-)	483	WP_111696535.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
DQN30_RS05165 (NCTC10839_01028)	pcnB	1020197..1021639 (-)	1443	WP_407920556.1	polynucleotide adenylyltransferase PcnB	-
DQN30_RS05170 (NCTC10839_01029)	dksA	1021803..1022240 (-)	438	WP_005627987.1	RNA polymerase-binding protein DksA	-
DQN30_RS05175 (NCTC10839_01030)	rec2	1022500..1024866 (+)	2367	WP_111696536.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQN30_RS05180 (NCTC10839_01031)	msbA	1024907..1026670 (+)	1764	WP_111696537.1	lipid A ABC transporter ATP-binding protein/permease MsbA	-
DQN30_RS05185 (NCTC10839_01032)	lpxK	1026743..1027741 (+)	999	WP_111696538.1	tetraacyldisaccharide 4'-kinase	-
DQN30_RS05190 (NCTC10839_01033)	-	1027746..1027919 (+)	174	WP_172454068.1	Trm112 family protein	-
DQN30_RS05195 (NCTC10839_01034)	kdsB	1027923..1028687 (+)	765	WP_111696540.1	3-deoxy-manno-octulosonate cytidylyltransferase	-

Sequence

Protein

• Length: 788 a.a.
• Molecular weight: 89626.18 Da
• Isoelectric Point: 9.9901

>NTDB_id=1142202 DQN30_RS05175 WP_111696536.1 1022500..1024866(+) (rec2) [Haemophilus haemolyticus strain NCTC10839]
MKLNLITLVILLIVADLTLLFLPQSWLLPWQVALVIALALIFLFIFVRRNFLVFLAFFVVSLGYTHHSALSLLQQAQSIT
AQKQVVTFKIQEILHQQDYQTLIATATLADNLRAQRIFLNWKAKEAPQLSEIWQAEISLRPLSARLNFGGFDRQQWYFSK
GITAVGTVKSAVKIADVSSLRAERLKQVKKQTEGLSLQGLLLALAFGERAWLDKTTWSIYQQTNTAHLIAISGLHIGLAM
GIGFYLARVVQVFFPTRFIHPYFPLVFGVLFALIYAYLAGFSVPTFRAISALVFIFFVQIMRRYYSPLQLFMLVVGFLLF
CDPLMPLSISFWLSCGSVGCLIVWYRYVPFSLFQWKNRPFSPKVRWILSLFHLQFGLLLFFTPLQLFLFNGLSLSGFLAN
LIVVPLYSFFLVPLILFAVFTNGACFSWQLANKLAEGITWLISVFQGNWFNVSFNLALVLTALCAGIFMLIIWSIYREPE
ISSSTKQIKRARFFTLNLSKSLLKNDRINALRCSFGIMSLCFMILLFKQLSKPIWQVDTLDVGQGLATLIVKNGKGILYD
TGPAWQGGDMAELEILPYLQREGVTLEKLILSHDDNDHAGGASTILKAYPNIEFITPSRKNYGKNHRTFCTAGRHWDWQG
LHFQILSPHSIVERADNPHSCVILIDDGKHSVLLTGDAETKNEQIFARTLGKIDVLQVGHHGSKTSTSEYLLSQVRPDIA
IISSGRWNPWKFPHYSVMERLHRYKSAVENTAISGQVRVNFFKDRLEIQQARTEFSPWYARVIGFSSE

Nucleotide

• Length: 2367 bp

>NTDB_id=1142202 DQN30_RS05175 WP_111696536.1 1022500..1024866(+) (rec2) [Haemophilus haemolyticus strain NCTC10839]
ATGAAATTAAACTTAATAACTTTAGTTATCTTGTTGATTGTTGCGGATTTAACGTTGTTATTTCTACCGCAGTCATGGCT
ATTGCCTTGGCAAGTTGCTCTGGTTATTGCGCTTGCCTTGATTTTTCTTTTTATCTTTGTGCGCAGAAACTTCTTGGTTT
TTCTTGCTTTTTTTGTTGTTTCTCTCGGTTATACACATCATTCAGCGCTTAGCTTGTTACAACAAGCACAAAGTATTACC
GCTCAAAAACAAGTGGTGACTTTTAAGATCCAAGAAATTTTACACCAACAGGATTATCAAACTCTTATCGCCACAGCAAC
ATTGGCGGATAACTTACGAGCGCAACGAATTTTTTTAAATTGGAAGGCAAAAGAAGCGCCTCAATTATCGGAAATTTGGC
AAGCGGAAATTTCCTTACGGCCACTTTCTGCGCGATTAAATTTTGGTGGATTTGATCGGCAACAATGGTATTTTTCAAAG
GGAATTACCGCTGTTGGAACCGTAAAAAGTGCGGTAAAAATTGCTGATGTTTCATCATTGCGAGCAGAAAGATTGAAACA
AGTAAAAAAGCAAACGGAAGGATTATCTCTACAAGGTTTATTGTTAGCGTTAGCTTTTGGCGAACGAGCGTGGTTAGATA
AAACCACTTGGTCAATTTACCAGCAAACCAATACCGCACATCTTATTGCTATTTCTGGCTTACATATTGGGTTGGCTATG
GGGATTGGATTTTACTTGGCGCGTGTTGTGCAAGTATTTTTCCCCACCCGTTTTATTCATCCTTATTTTCCTTTAGTTTT
TGGTGTTTTATTTGCTTTAATTTATGCGTATTTGGCTGGTTTTAGCGTGCCAACTTTTCGTGCCATTTCAGCACTTGTTT
TCATTTTCTTCGTTCAAATAATGAGGCGATATTATTCACCCCTTCAGCTTTTTATGCTGGTTGTCGGATTCTTGCTTTTC
TGCGATCCATTAATGCCTCTTTCGATCAGTTTTTGGCTTTCTTGTGGATCAGTTGGTTGTTTGATCGTCTGGTATCGTTA
TGTGCCTTTTTCTCTTTTTCAATGGAAAAATCGCCCCTTTTCACCAAAAGTGCGGTGGATTTTGAGTTTATTTCATTTGC
AATTTGGGTTATTACTCTTTTTTACGCCTTTGCAACTTTTTTTATTTAATGGCTTATCGTTGAGTGGATTTTTAGCCAAT
CTTATTGTCGTACCACTTTATAGTTTTTTCCTCGTACCCTTGATTTTATTTGCTGTTTTTACTAATGGAGCTTGTTTTTC
TTGGCAACTTGCAAACAAACTAGCGGAAGGAATCACTTGGTTAATTTCTGTTTTTCAAGGAAATTGGTTTAATGTTTCAT
TTAATTTAGCGCTGGTTTTAACCGCACTTTGTGCAGGAATTTTTATGCTAATTATTTGGAGTATTTACCGAGAACCCGAG
ATTTCATCATCAACCAAACAAATAAAACGAGCAAGATTTTTTACATTAAATCTCAGTAAATCTTTGCTAAAAAATGATCG
AATCAACGCTCTGCGATGTTCTTTCGGCATTATGTCGCTGTGTTTTATGATTTTGTTGTTCAAGCAACTAAGCAAGCCAA
TTTGGCAGGTAGATACTTTAGATGTGGGGCAGGGCTTAGCTACGTTGATTGTGAAAAATGGCAAAGGGATTCTTTATGAT
ACAGGACCTGCATGGCAAGGGGGGGATATGGCTGAGTTAGAAATTTTGCCTTATTTACAAAGAGAAGGGGTTACTTTGGA
AAAGTTGATTTTGAGCCACGACGATAACGATCATGCTGGTGGTGCTTCGACAATTTTAAAGGCGTATCCGAATATAGAAT
TTATTACCCCTTCACGAAAAAACTATGGGAAAAATCACCGCACTTTTTGTACTGCTGGACGTCATTGGGATTGGCAAGGG
CTACATTTTCAAATACTCTCGCCGCATTCTATTGTGGAGAGAGCAGATAATCCCCATTCTTGTGTGATTTTAATCGATGA
TGGAAAGCATAGCGTTTTGCTGACAGGCGATGCTGAAACAAAAAATGAGCAAATTTTTGCCCGCACTTTAGGCAAAATCG
ATGTGTTGCAAGTGGGGCATCATGGGAGTAAAACATCGACAAGTGAATATTTACTTTCGCAGGTGCGACCAGATATAGCC
ATTATTTCTAGTGGGCGTTGGAATCCGTGGAAATTCCCTCATTATTCGGTTATGGAAAGGCTACATCGTTATAAAAGTGC
GGTAGAAAATACCGCTATTTCAGGGCAAGTACGGGTAAATTTTTTTAAAGACCGATTAGAAATCCAACAAGCACGCACAG
AATTTTCCCCTTGGTATGCGCGTGTAATTGGATTCTCGAGCGAATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (26-171)

• Competence protein (Competence) (204-473)

• Metallo-beta-lactamase superfamily (Lactamase_B) (541-725)

3D structure

• AlphaFold DB: A0A2X4U305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rec2	Haemophilus influenzae Rd KW20	89.848	100	0.898