Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPOKI422_RS02810 Genome accession   NZ_CP006824
Coordinates   575764..577548 (-) Length   594 a.a.
NCBI ID   WP_025309720.1    Uniprot ID   -
Organism   Helicobacter pylori oki422     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 570764..582548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPOKI422_RS02780 (HPOKI422_02870) - 571170..571418 (+) 249 WP_025276798.1 RNA recognition motif domain-containing protein -
  HPOKI422_RS02785 (HPOKI422_02875) - 571615..572436 (-) 822 WP_025276799.1 glycosyltransferase family 25 protein -
  HPOKI422_RS02790 (HPOKI422_02885) trxB 572793..573728 (-) 936 WP_000564419.1 thioredoxin-disulfide reductase -
  HPOKI422_RS02795 (HPOKI422_02890) trxA 573734..574054 (-) 321 WP_000020199.1 thioredoxin -
  HPOKI422_RS02800 (HPOKI422_02895) - 574143..574487 (-) 345 WP_015427936.1 YraN family protein -
  HPOKI422_RS02805 (HPOKI422_02900) - 574488..575753 (-) 1266 WP_025366398.1 homoserine dehydrogenase -
  HPOKI422_RS02810 (HPOKI422_02905) uvrC 575764..577548 (-) 1785 WP_025309720.1 excinuclease ABC subunit UvrC Machinery gene
  HPOKI422_RS02815 (HPOKI422_02910) - 577549..578010 (-) 462 WP_025275828.1 hypothetical protein -
  HPOKI422_RS02820 (HPOKI422_02915) - 578002..578181 (+) 180 WP_000468792.1 hypothetical protein -
  HPOKI422_RS02825 (HPOKI422_02920) - 578193..578834 (-) 642 WP_025276802.1 ATP-binding cassette domain-containing protein -
  HPOKI422_RS02830 (HPOKI422_02925) - 578838..580499 (-) 1662 WP_025275830.1 ABC transporter permease/substrate-binding protein -
  HPOKI422_RS02835 (HPOKI422_02930) - 580568..581014 (-) 447 WP_001081241.1 hypothetical protein -
  HPOKI422_RS02840 (HPOKI422_02935) motB 581011..581784 (-) 774 WP_025275831.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68580.79 Da        Isoelectric Point: 9.6316

>NTDB_id=114215 HPOKI422_RS02810 WP_025309720.1 575764..577548(-) (uvrC) [Helicobacter pylori oki422]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSICNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=114215 HPOKI422_RS02810 WP_025309720.1 575764..577548(-) (uvrC) [Helicobacter pylori oki422]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
GCTCTATATCGGTAAAGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCTGCAATAATGAAATCACGCCCA
ACCATCGCGCAAGCTTACGAATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACGATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAATATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAGTTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGCAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCCAATAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGACATTTTTGCTTTTTATGGCGCGAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAGGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATTCTATTAAAC
GCTTGTTCTAATGAAGCGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGAGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTAATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

98.653

100

0.987

Multiple sequence alignment