Detailed information    

insolico Bioinformatically predicted

Overview

Name   rcrQ   Type   Regulator
Locus tag   DQL01_RS12460 Genome accession   NZ_LS483451
Coordinates   1845571..1846602 (-) Length   343 a.a.
NCBI ID   WP_138038883.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836166     
Function   regulate competence (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1836269..1858894 1845571..1846602 within 0


Gene organization within MGE regions


Location: 1836269..1858894
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL01_RS09840 groL 1836269..1837891 (-) 1623 WP_000031573.1 chaperonin GroEL -
  DQL01_RS09845 groES 1837907..1838191 (-) 285 WP_000917330.1 co-chaperone GroES -
  DQL01_RS09850 - 1838404..1839801 (+) 1398 Protein_1865 ISNCY family transposase -
  DQL01_RS12675 - 1839874..1839999 (+) 126 WP_001258158.1 hypothetical protein -
  DQL01_RS09860 ssbB/cilA 1840234..1840629 (-) 396 WP_000282467.1 single-stranded DNA-binding protein Machinery gene
  DQL01_RS09865 - 1840706..1841467 (-) 762 WP_050115111.1 SDR family NAD(P)-dependent oxidoreductase -
  DQL01_RS09870 ytpR 1841500..1842126 (-) 627 WP_000578309.1 YtpR family tRNA-binding protein -
  DQL01_RS09875 - 1842142..1842459 (-) 318 WP_000615767.1 thioredoxin family protein -
  DQL01_RS09880 - 1842456..1842755 (-) 300 WP_001013974.1 DUF4651 domain-containing protein -
  DQL01_RS12455 - 1842849..1842995 (+) 147 WP_050125336.1 hypothetical protein -
  DQL01_RS09890 - 1842965..1843243 (-) 279 WP_222149965.1 hypothetical protein -
  DQL01_RS09895 - 1843403..1844077 (-) 675 WP_000725749.1 LiaF transmembrane domain-containing protein -
  DQL01_RS09900 - 1844083..1844529 (-) 447 WP_000776589.1 LytTR family DNA-binding domain-containing protein -
  DQL01_RS09905 - 1844643..1845146 (-) 504 WP_000800942.1 phosphatase PAP2 family protein -
  DQL01_RS09910 - 1845143..1845505 (-) 363 WP_000078805.1 DUF2200 domain-containing protein -
  DQL01_RS12460 rcrQ 1845571..1846602 (-) 1032 WP_138038883.1 ABC transporter ATP-binding protein Regulator
  DQL01_RS12465 - 1846609..1847432 (-) 824 Protein_1879 ABC transporter permease -
  DQL01_RS09920 - 1847449..1847920 (-) 472 Protein_1880 MarR family winged helix-turn-helix transcriptional regulator -
  DQL01_RS09930 - 1848044..1848760 (-) 717 WP_000532876.1 YebC/PmpR family DNA-binding transcriptional regulator -
  DQL01_RS09940 ply 1849641..1851056 (-) 1416 WP_001284359.1 cholesterol-dependent cytolysin pneumolysin -
  DQL01_RS09945 - 1851067..1851477 (-) 411 WP_000595764.1 hypothetical protein -
  DQL01_RS09950 - 1851470..1852078 (-) 609 WP_000083614.1 hypothetical protein -
  DQL01_RS09955 - 1852091..1852549 (-) 459 WP_000186955.1 DUF4231 domain-containing protein -
  DQL01_RS09960 - 1852674..1853073 (+) 400 Protein_1886 transposase family protein -
  DQL01_RS09965 - 1853551..1854384 (+) 834 WP_044793671.1 glycerophosphodiester phosphodiesterase family protein -
  DQL01_RS09970 - 1854403..1855464 (+) 1062 WP_000475762.1 extracellular solute-binding protein -
  DQL01_RS09975 - 1855481..1856485 (+) 1005 WP_061841860.1 ABC transporter ATP-binding protein -
  DQL01_RS09980 - 1856497..1858191 (+) 1695 WP_069288023.1 ABC transporter permease -
  DQL01_RS09985 - 1858193..1858894 (+) 702 WP_001054457.1 MgtC/SapB family protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 37951.23 Da        Isoelectric Point: 4.5159

>NTDB_id=1142110 DQL01_RS12460 WP_138038883.1 1845571..1846602(-) (rcrQ) [Streptococcus pneumoniae strain 4041STDY6836166]
MGFLLMGALFIVLPRTMVSAKRINQVLYLHSSIQNPVQVQLTDENFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTV
AFIGSTGSGKSTLVNLIPRFYDVSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNLIGISDERMMEASKAVGIHHFIMTLPDGYDTILDDTVTLSVG
QKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQKAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEE
LMAQGGFYADLYNSQFTEDEAEE

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=1142110 DQL01_RS12460 WP_138038883.1 1845571..1846602(-) (rcrQ) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGGGCTTCCTTCTCATGGGAGCACTCTTCATCGTTCTTCCCCGAACTATGGTCTCTGCTAAGCGGATTAATCAAGTTTT
ATATTTGCATTCTTCTATCCAAAACCCTGTTCAAGTGCAGCTGACTGATGAAAACTTCAAAGGTCAGGTCGAGTTTAAGG
ATGTGACCTTCCGCTATGCGGCAAATTCGGAGGCAGTTATTGAACATGTTAGCTTTAAAGCAGAAACTGGTCAAACAGTG
GCCTTTATTGGGTCAACAGGTTCTGGTAAATCAACTCTGGTCAATCTGATTCCACGTTTCTACGACGTGTCAGCAGGAGA
AATTCTGGTGGACGGTGTCAATGTTCAAGACTATGACTTCTCTGCGACAGCTCATGCTGGTCAAAAGGTTGCCATTGTTG
GGCCGACTGGGACTGGTAAGACAACCATTGTCAATCTTTTGATGAAATTCTATGAGATTGATAAGGGAAGTATTCACATT
GATGGTGTGGATACCAAGGCTATGACGCGTTCAGAAGTGCATGATGCCTTTTCAATGGTCTTGCAGGATACCTGGCTCTT
TGAAGGAACTATTCGAGACAATCTCATCTATAATCTAATAGGGATTAGTGATGAACGAATGATGGAAGCTAGTAAGGCTG
TGGGAATTCACCACTTTATTATGACCTTGCCAGATGGCTATGATACCATCTTGGATGACACCGTGACCTTGTCTGTAGGA
CAAAAACAACTATTGACTATTGCTCGTGCCCTTCTTAAGGATGCACCGCTTTTGATTTTGGATGAGGCGACTTCTTCTGT
TGACACACGGACAGAGGAATTGATCCAAAAAGCCATGGACCGTTTGATGGAAGGACGCACATCCTTTGTCATTGCCCACC
GCTTGTCAACCATCCGAAATGCAGACTTGATCTTGGTCATGAAAGATGGAAATATCATCGAGCAAGGCAACTATGAGGAA
CTGATGGCGCAAGGTGGCTTCTACGCTGACTTGTACAATAGTCAATTTACAGAAGATGAAGCAGAAGAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(120-265)

ABC transporter (ABC_tran)

(68-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rcrQ Streptococcus mutans UA159

80.357

65.306

0.525
  rcrP Streptococcus mutans UA159

37.572

100

0.379

Multiple sequence alignment