Detailed information NTG1141927

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQK98_RS09655
• Genome accession: NZ_LS483449
• Coordinates: 1819258..1820295 (-)
• Length: 345 a.a.
• NCBI ID: WP_001839571.1
• Uniprot ID: A0A4J2A4T3
• Organism: Streptococcus pneumoniae strain 4041STDY6836170
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1814258..1825295

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK98_RS09630	-	1815071..1816402 (-)	1332	WP_000390039.1	hemolysin family protein	-
DQK98_RS09635	endA	1816619..1817443 (-)	825	WP_111688178.1	DNA-entry nuclease EndA	Machinery gene
DQK98_RS09640	-	1817482..1817670 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
DQK98_RS09645	murA	1817663..1818946 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQK98_RS09650	-	1818970..1819200 (-)	231	WP_000250382.1	DUF1146 family protein	-
DQK98_RS09655	sepM	1819258..1820295 (-)	1038	WP_001839571.1	SepM family pheromone-processing serine protease	Regulator
DQK98_RS09660	coaD	1820279..1820767 (-)	489	WP_001280769.1	pantetheine-phosphate adenylyltransferase	-
DQK98_RS09665	rsmD	1820757..1821296 (-)	540	WP_000706965.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQK98_RS09670	asnA	1821361..1822353 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
DQK98_RS09680	-	1822465..1823148 (-)	684	WP_001016913.1	Bax inhibitor-1 family protein	-
DQK98_RS09685	-	1823204..1823944 (-)	741	WP_000152678.1	TrmH family RNA methyltransferase	-
DQK98_RS09690	-	1823978..1824256 (+)	279	WP_001174613.1	acylphosphatase	-
DQK98_RS09695	yidC	1824334..1825260 (+)	927	WP_000835942.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37519.54 Da
• Isoelectric Point: 5.0724

>NTDB_id=1141927 DQK98_RS09655 WP_001839571.1 1819258..1820295(-) (sepM) [Streptococcus pneumoniae strain 4041STDY6836170]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHIIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=1141927 DQK98_RS09655 WP_001839571.1 1819258..1820295(-) (sepM) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATAATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

3D structure

• AlphaFold DB: A0A4J2A4T3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591