Detailed information NTG1141879

Bioinformatically predicted

Overview

• Name: radA
• Type: Machinery gene
• Locus tag: DQK98_RS00145
• Genome accession: NZ_LS483449
• Coordinates: 25172..26533 (+)
• Length: 453 a.a.
• NCBI ID: WP_074017595.1
• Uniprot ID: A0A237IXT5
• Organism: Streptococcus pneumoniae strain 4041STDY6836170
• Function: homologous recombination (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	27465..28816	25172..26533	flank	932

Gene organization within MGE regions

Location: 25172..28816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK98_RS00145	radA	25172..26533 (+)	1362	WP_074017595.1	DNA repair protein RadA	Machinery gene
DQK98_RS00150	-	26606..27103 (+)	498	WP_001809263.1	beta-class carbonic anhydrase	-
DQK98_RS00155	-	27124..27411 (+)	288	Protein_23	PrsW family intramembrane metalloprotease	-
DQK98_RS00160	-	27465..28816 (+)	1352	WP_088778796.1	IS3 family transposase	-

Sequence

Protein

• Length: 453 a.a.
• Molecular weight: 49432.95 Da
• Isoelectric Point: 6.5137

>NTDB_id=1141879 DQK98_RS00145 WP_074017595.1 25172..26533(+) (radA) [Streptococcus pneumoniae strain 4041STDY6836170]
MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKNARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRV
LGGGVVPGSLVLIGGDPGIGKSTLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAK
RTTTGLDFNRASLIMAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGELGLTGEIR
RVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKKVFA

Nucleotide

• Length: 1362 bp

>NTDB_id=1141879 DQK98_RS00145 WP_074017595.1 25172..26533(+) (radA) [Streptococcus pneumoniae strain 4041STDY6836170]
ATCGCAAAGAAAAAAGCGACATTTGTATGTCAAAATTGTGGGTATAATTCCCCTAAATATCTGGGACGTTGCCCCAACTG
TGGGTCTTGGTCTTCTTTTGTGGAAGAGGTTGAGGTTGCCGAGGTCAAGAATGCGCGTGTGTCCTTGACAGGTGAGAAAA
CCAAGCCCATGAAACTAGCTGAGGTGACTTCCATCAATGTCAATCGAACCAAGACGGAGATGGAGGAATTCAATCGTGTG
CTTGGAGGCGGAGTGGTACCAGGAAGTCTCGTCCTCATCGGTGGGGATCCTGGGATTGGGAAATCAACTCTTCTCCTACA
AGTCTCAACCCAGTTGTCCCAAGTGGGGACAGTTCTCTATGTCAGTGGGGAGGAGTCTGCCCAGCAGATTAAACTACGTG
CAGAGCGCTTAGGTGATATTGATAGTGAGTTTTATCTCTATGCAGAGACCAATATGCAGAGTGTTCGTGCAGAAGTGGAG
CGTATCCAGCCAGACTTTCTCATTATTGATTCCATCCAGACCATCATGTCTCCTGAGATTTCAGGGGTGCAGGGGTCTGT
TTCTCAGGTGCGTGAAGTGACCGCTGAACTCATGCAGTTGGCCAAGACTAATAACATTGCCATCTTTATCGTAGGTCATG
TGACCAAAGAAGGAACCTTGGCTGGGCCTCGTATGTTGGAGCATATGGTGGATACGGTGCTTTACTTTGAAGGGGAGCGT
CACCACACCTTTCGTATTTTGAGAGCGGTCAAAAATCGTTTTGGTTCCACTAATGAGATTGGGATTTTTGAGATGCAGTC
GGGCGGCTTGGTTGAGGTACTCAATCCGAGTCAAGTTTTCCTAGAAGAGCGTTTGGATGGGGCAACTGGTTCCTCCATCG
TTGTAACCATGGAAGGGACGCGTCCGATTTTGGCGGAGGTTCAGGCTTTGGTAACACCGACCATGTTTGGAAATGCCAAG
CGTACTACGACAGGACTTGATTTTAACCGTGCTAGCTTGATTATGGCTGTTTTGGAAAAACGGGCAGGGCTTCTCTTGCA
AAATCAGGATGCCTATCTCAAATCTGCTGGTGGTGTTAAATTGGATGAACCTGCCATTGACTTGGCTGTTGCAGTTGCTA
TTGCTTCGAGCTACAAAGACAAGCCAACTAATCCTCAGGAATGTTTTGTCGGAGAACTGGGCTTGACAGGAGAGATTCGG
CGCGTGAATCGTATTGAGCAACGCATCAACGAAGCTGCTAAACTGGGCTTTACTAAGATTTATGTACCTAAGAATTCCTT
GACAGGAATCACTCTGCCTAAGGAAATTCAGGTCATTGGCGTGACAACGATTCAGGAAGTTTTGAAAAAGGTCTTTGCAT
AA

Domains

Predicted by InterproScan.

• Rubredoxin metal binding domain (Zn_ribbon_LapB) (8-35)

• AAA domain (AAA_25) (63-218)

• Subunit ChlI of Mg-chelatase (ChlI) (360-425)

3D structure

• PDB: 8RXC

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
radA	Streptococcus pneumoniae Rx1	100	100	1
radA	Streptococcus pneumoniae D39	100	100	1
radA	Streptococcus pneumoniae R6	100	100	1
radA	Streptococcus pneumoniae TIGR4	100	100	1
radA	Streptococcus mitis NCTC 12261	99.558	100	0.996
radA	Streptococcus mitis SK321	99.558	100	0.996
radA	Bacillus subtilis subsp. subtilis str. 168	63.135	100	0.631