Detailed information NTG1141850

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQK99_RS10100
• Genome accession: NZ_LS483448
• Coordinates: 1844389..1845426 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 4041STDY6836167
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1839389..1850426

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK99_RS10075	-	1840128..1841459 (-)	1332	WP_000390042.1	hemolysin family protein	-
DQK99_RS10080	endA	1841750..1842574 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
DQK99_RS10085	-	1842613..1842801 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
DQK99_RS10090	murA	1842794..1844077 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQK99_RS10095	-	1844101..1844331 (-)	231	WP_000250390.1	DUF1146 family protein	-
DQK99_RS10100	sepM	1844389..1845426 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
DQK99_RS10105	coaD	1845410..1845898 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
DQK99_RS10110	rsmD	1845888..1846427 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQK99_RS10115	asnA	1846492..1847484 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
DQK99_RS10125	-	1847596..1848279 (-)	684	WP_001016913.1	Bax inhibitor-1 family protein	-
DQK99_RS10130	-	1848335..1849075 (-)	741	WP_000152679.1	TrmH family RNA methyltransferase	-
DQK99_RS10135	-	1849109..1849387 (+)	279	WP_001174614.1	acylphosphatase	-
DQK99_RS10140	yidC	1849465..1850391 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=1141850 DQK99_RS10100 WP_001813016.1 1844389..1845426(-) (sepM) [Streptococcus pneumoniae strain 4041STDY6836167]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=1141850 DQK99_RS10100 WP_001813016.1 1844389..1845426(-) (sepM) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588