Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   DQL20_RS03075 Genome accession   NZ_LS483444
Coordinates   563611..565878 (-) Length   755 a.a.
NCBI ID   WP_006596774.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC13166     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 558611..570878
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL20_RS03050 (NCTC11371_00608) ileS 559164..561956 (+) 2793 WP_006596778.1 isoleucine--tRNA ligase -
  DQL20_RS03055 (NCTC11371_00609) - 562017..562451 (+) 435 WP_006597133.1 GNAT family N-acetyltransferase -
  DQL20_RS03060 (NCTC11371_00610) - 562532..562834 (-) 303 WP_006596776.1 DUF1827 family protein -
  DQL20_RS03065 (NCTC11371_00611) - 562902..563351 (-) 450 WP_006596775.1 NUDIX hydrolase -
  DQL20_RS03075 (NCTC11371_00612) clpE 563611..565878 (-) 2268 WP_006596774.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQL20_RS03080 (NCTC11371_00613) - 566108..566338 (+) 231 WP_006596773.1 DUF1797 family protein -
  DQL20_RS03085 (NCTC11371_00614) - 566495..567349 (+) 855 WP_006596772.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  DQL20_RS03090 (NCTC11371_00615) - 567482..568336 (+) 855 WP_006596771.1 NAD(P)H-hydrate dehydratase -
  DQL20_RS03095 (NCTC11371_00616) xseA 568449..569789 (+) 1341 WP_006596770.1 exodeoxyribonuclease VII large subunit -
  DQL20_RS03100 (NCTC11371_00617) - 569767..569979 (+) 213 WP_006596769.1 exodeoxyribonuclease VII small subunit -
  DQL20_RS03105 (NCTC11371_00618) - 569976..570863 (+) 888 WP_006596768.1 polyprenyl synthetase family protein -

Sequence

Protein


Download         Length: 755 a.a.        Molecular weight: 83689.69 Da        Isoelectric Point: 5.0141

>NTDB_id=1141735 DQL20_RS03075 WP_006596774.1 563611..565878(-) (clpE) [Streptococcus australis strain NCTC13166]
MLCQNCKINDSTIHLYTNVNGHQQQVDLCQNCYQIMKTDPNNSLLAGLNQQNRGGGDPFEDFFNQLGNFQAPQEPQTPPT
QSGGGYGGGNGYGSNGNGRSSGPNRAQAKQQPKGLLEEFGINVTEIARRGDIDPVIGRDEEILRVIEILNRRTKNNPVLI
GEPGVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQQLMEEIRRREDVILFIDEIHEIVGA
GSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHYT
DGAIEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKY
KEMQGQQVTDQDTPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLAADLKAHVIGQDEAVEKIAKAIRRNRVGLGTPN
RPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLIL
LDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSILGELGNFFSPEFM
NRFDGIIEFKSLSKENLLQIVTLMLDDVNQRLAHNDIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYL
ENPSEKDLKAVMTSNGKICIKGKNKPANEAEKGTE

Nucleotide


Download         Length: 2268 bp        

>NTDB_id=1141735 DQL20_RS03075 WP_006596774.1 563611..565878(-) (clpE) [Streptococcus australis strain NCTC13166]
ATGCTTTGTCAAAACTGTAAAATCAACGATTCAACCATTCATCTTTATACAAATGTGAATGGTCACCAACAACAAGTAGA
CCTTTGCCAGAACTGCTATCAAATTATGAAAACCGATCCTAACAATAGTCTCCTGGCAGGATTAAACCAACAAAATCGCG
GAGGGGGGGATCCTTTTGAAGATTTCTTCAATCAACTGGGCAACTTCCAGGCTCCGCAAGAACCTCAAACCCCTCCGACC
CAATCTGGAGGAGGCTATGGTGGAGGAAATGGCTATGGCTCAAATGGGAACGGACGTTCTTCAGGACCGAATAGAGCCCA
AGCCAAACAACAACCAAAGGGCCTCTTAGAAGAGTTCGGAATCAATGTCACAGAAATTGCTCGTCGTGGCGATATCGATC
CGGTCATTGGTCGTGATGAAGAGATTCTCCGTGTCATCGAAATCCTCAACCGTCGTACCAAAAACAACCCTGTCTTGATC
GGTGAACCTGGTGTCGGGAAAACTGCTGTCGTAGAAGGCCTGGCTCAAAAGATTGTCGATGGGGATGTCCCTCATAAATT
GCAAGGCAAGCAAGTTATTCGCTTAGACGTTGTTAGTCTTGTTCAAGGAACTGGGATCCGAGGCCAATTTGAAGAGCGCA
TGCAACAATTAATGGAGGAAATCCGTCGCCGTGAAGATGTGATTTTATTCATCGACGAAATTCATGAAATCGTCGGTGCT
GGATCTGCTGGAGACGGCAACATGGATGCTGGAAATATCCTCAAACCGGCCCTCGCTCGTGGCGAATTGCAATTAGTCGG
TGCGACAACACTTAATGAATACCGGATTATCGAGAAGGATGCAGCACTTGAGCGCCGGATGCAACCCGTTAAGGTCGATG
AGCCAACGGTTGAAGAAACTATCACCATCCTCAAAGGGATTCAAAAGAAATATGAGGACTACCACCACGTTCACTACACA
GATGGGGCCATCGAAGCTGCAGCACTCCTCTCCAATCGCTATATCCAAGACCGCTTCTTGCCCGACAAGGCCATTGACCT
CTTGGATGAAGCTGGCTCTAAGATGAATTTAACCCTCAATTTCGTCGATCCAAAGGTCATTGACCAACGCTTAATTGAAG
CTGAAAATCTCAAAGCCCAGGCGACGCGTGATGAAGATTTCGAAAAAGCTGCCTACTTCCGTGACCAAATCGCTAAGTAC
AAAGAAATGCAAGGGCAACAGGTCACTGATCAAGATACGCCAGTCATTAGCGAAAAGACCATCGAACACATCGTCGAACA
AAAGACCAATATTCCAGTTGGAGATTTGAAAGAAAAAGAACAATCCCAATTGATCAATTTGGCAGCTGATTTGAAGGCTC
ATGTCATCGGCCAAGATGAGGCTGTTGAAAAAATTGCTAAGGCTATCCGTCGTAATCGGGTAGGACTTGGAACGCCCAAC
CGTCCAATCGGTAGCTTCCTCTTTGTTGGACCGACTGGCGTCGGGAAGACAGAGTTGTCCAAACAATTGGCTATCGAACT
CTTCGGTTCTGCTGATAGTATGATTCGCTTTGATATGAGCGAATACATGGAGAAACATGCTGTTGCTAAACTGGTCGGCG
CCCCTCCAGGATATGTTGGTTACGAAGAAGCTGGCCAGCTGACTGAAAAGGTGCGTCGCAACCCTTACTCTCTCATTCTC
TTAGATGAGGTTGAAAAGGCCCATCCTGATGTCATGCATATGTTCCTCCAAGTCTTGGATGATGGTCGCTTGACAGATGG
TCAAGGACGAACAGTAAGCTTCAAAGATACCATCATCATCATGACTTCAAATGCGGGAACTGGAAAAGCCGAGGCTAACG
TTGGTTTTGGGGCGGCTCGTGAAGGACGTACCAATTCTATCCTAGGTGAACTTGGAAACTTCTTTAGTCCAGAATTCATG
AACCGGTTTGATGGTATTATTGAATTTAAATCCTTATCTAAAGAAAACCTCCTTCAAATCGTCACTCTTATGCTCGATGA
TGTCAATCAACGCCTGGCCCACAATGATATCCACCTCGATGTTACCGATAAAGTCAAGGAAAAATTGGTTGATTTGGGCT
ACGATCCAAAAATGGGAGCTCGTCCACTTCGTCGTACCATTCAGGACTATATCGAAGATGCCATTACAGATTACTACTTA
GAAAATCCTAGTGAAAAAGATCTGAAGGCTGTCATGACCAGCAATGGAAAGATTTGCATTAAAGGAAAGAACAAACCTGC
TAACGAGGCAGAAAAAGGAACTGAATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(296-393)

AAA domain (Cdc48 subfamily) (AAA_2)

(481-644)

ATPase family associated with various cellular activities (AAA) (AAA)

(158-277)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(652-726)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

87.169

100

0.873
  clpE Streptococcus pneumoniae D39

87.169

100

0.873
  clpE Streptococcus pneumoniae R6

87.169

100

0.873
  clpE Streptococcus pneumoniae TIGR4

87.169

100

0.873
  clpE Streptococcus mutans UA159

85.18

99.205

0.845
  clpC Lactococcus lactis subsp. cremoris KW2

76.058

100

0.762
  clpC Bacillus subtilis subsp. subtilis str. 168

50.954

90.199

0.46
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.804

83.046

0.405
  clpC Streptococcus pneumoniae Rx1

47.792

83.974

0.401
  clpC Streptococcus pneumoniae D39

47.792

83.974

0.401
  clpC Streptococcus pneumoniae TIGR4

47.634

83.974

0.4
  clpC Streptococcus thermophilus LMD-9

47.377

83.311

0.395
  clpC Streptococcus thermophilus LMG 18311

47.209

83.046

0.392
  clpC Streptococcus mutans UA159

47.504

82.252

0.391

Multiple sequence alignment