Detailed information NTG0114165

Bioinformatically predicted

Overview

• Name: comB2
• Type: Machinery gene
• Locus tag: HPOKI128_RS05825
• Genome accession: NZ_CP006822
• Coordinates: 1221521..1221802 (+)
• Length: 93 a.a.
• NCBI ID: WP_001272686.1
• Uniprot ID: G2MDJ3
• Organism: Helicobacter pylori oki128
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1216521..1226802

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPOKI128_RS05805 (HPOKI128_06005)	groES	1217098..1217454 (-)	357	WP_000671954.1	co-chaperone GroES	-
HPOKI128_RS05810 (HPOKI128_06010)	dnaG	1217730..1219409 (+)	1680	WP_025288474.1	DNA primase	-
HPOKI128_RS05815 (HPOKI128_06015)	-	1219406..1220458 (+)	1053	WP_025288475.1	MnmA/TRMU family protein	-
HPOKI128_RS05820 (HPOKI128_06020)	-	1220549..1221376 (+)	828	WP_025288476.1	DUF5718 family protein	-
HPOKI128_RS05825 (HPOKI128_06025)	comB2	1221521..1221802 (+)	282	WP_001272686.1	TrbC/VirB2 family protein	Machinery gene
HPOKI128_RS05830 (HPOKI128_06030)	comB3	1221802..1222065 (+)	264	WP_000584953.1	hypothetical protein	Machinery gene
HPOKI128_RS05835 (HPOKI128_06035)	-	1222067..1224433 (+)	2367	Protein_1123	VirB4 family type IV secretion/conjugal transfer ATPase	-
HPOKI128_RS05840 (HPOKI128_06040)	-	1224756..1226096 (+)	1341	Protein_1124	COG3014 family protein	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10539.81 Da
• Isoelectric Point: 9.1450

>NTDB_id=114165 HPOKI128_RS05825 WP_001272686.1 1221521..1221802(+) (comB2) [Helicobacter pylori oki128]
MSAHFLKIIFLVGMCVSSLFAEGLEGFFNALEAQLKSPIAKGILMVIFIGIAIYVWRNLDRWKEILFTILGVVFGIFLFF
KAPSLANWFMGIF

Nucleotide

• Length: 282 bp

>NTDB_id=114165 HPOKI128_RS05825 WP_001272686.1 1221521..1221802(+) (comB2) [Helicobacter pylori oki128]
ATGTCCGCTCATTTTTTAAAAATCATTTTTTTAGTAGGCATGTGCGTTTCAAGTTTGTTCGCTGAAGGTTTAGAGGGGTT
TTTTAACGCCCTAGAAGCCCAGCTCAAAAGCCCCATCGCTAAGGGGATTTTAATGGTGATTTTCATAGGGATCGCTATTT
ATGTGTGGAGGAATTTAGACCGGTGGAAAGAGATTTTATTCACGATCCTTGGCGTGGTGTTTGGGATTTTTTTATTCTTT
AAAGCCCCGAGTTTAGCGAATTGGTTCATGGGAATTTTTTAA

Domains

Predicted by InterproScan.

• TrbC/VIRB2 pilin (TrbC) (6-89)

3D structure

• AlphaFold DB: G2MDJ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB2	Helicobacter pylori 26695	98.925	100	0.989